Radiation-induced apoptosis and limb teratogenesis in embryonic mice

Radiation Research

Volumn 151, Issue 1, 1999, Pages 63-68

  Wang, B ^a,b,c   Fujita, K ^c   Ohhira, C ^a,c   Watanabe, K ^c   Odaka, T ^a   Mitani, H ^b   Hayata, I ^a   Ohyama, H ^a   Yamada, T ^a   Shima, A ^b  

^a NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c TOHO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; EMBRYO; FORELIMB; LIMB BUD; LIMB DEVELOPMENT; LIMB MALFORMATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIATION INJURY; TERATOGENESIS; X RAY;

ABNORMALITIES, RADIATION-INDUCED; ANIMALS; APOPTOSIS; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; FORELIMB; LIMB BUD; LIMB DEFORMITIES, CONGENITAL; MALE; MICE; MICE, INBRED ICR; PREGNANCY;

ANIMALIA;

EID: 0032907839     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.2307/3579748     Document Type: Article

References (35)

1. J. F. R. Kerr, A. H. Wyllie and A. R. Currie, Apoptosis: A basic biological phenomenon with wide ranging implications in tissue kinetics. Br. J. Cancer 26, 239-257 (1972).
2. E. J. Sanders and M. A. Wride, Programmed cell death in development. Int. Rev. Cytol. 163, 105-173 (1995).
3. ICRP, Developmental Effects of Radiation on the Brain of the Embryo and Fetus, pp. 2-30. Publication 49, Annals of the ICRP, Pergamon Press, New York, 1986.
4. NCRP, Considerations Regarding the Unintended Radiation Exposure of the Embryo, Fetus or Nursing Child. Commentary No. 9, National Council on Radiation Protection and Measurements, Bethesda, MD, 1994.
5. L. B. Russell and W. L. Russell, An analysis of the changing radiation response of the developing mouse embryo. J. Cell Physiol. 43 (Suppl. 1), 1030-1049 (1957).
6. C. S. Potten, The significance of spontaneous and induced apoptosis in the gastrointestinal tract of mice. Cancer Metastasis Rev. 11, 179-195 (1992).
7. J. M. Lee, J. L. A. Abrahamson and A. Bernstein, DNA damage, oncogenesis and the p53 tumor-suppressor gene. Mutat. Res. 307, 573-581 (1994).
8. A. J. Levine, M. E. Perry, A. Chang, A. Silver, D. Dittmer, M. Wu and D. Welsh, The 1993 Walter Hubert Lecture: The role of the p53 tumor-suppressor gene in tumorigenesis. Br. J. Cancer. 69, 409-416 (1994).
9. B. W. Stewart, Mechanisms of apoptosis: Integration of genetic, biochemical, and cellular indicators. J. Natl. Cancer Inst. 86, 1286-1296 (1994).
10. M. Montenarch, Marker genes for cytotoxic exposure: p53. Stem Cells 13 (Suppl. 1), 136-141 (1995).
11. J. C. Reed, Regulation of apoptosis by bcl-2 family proteins and its role in cancer and chemoresistance. Curr. Opin. Oncol. 7, 541-546 (1995).
12. T. Norimura, S. Nomoto, M. Katsuki, Y. Gondo and S. Kondo, p53-dependent apoptosis suppresses radiation-induced teratogenesis. Nat. Med. 2, 577-580 (1996).
13. T. Norimura, p53 guards against birth defects. J. Radiat. Res. 37, 287 (1996). [Abstract]
14. R. L. Brent, Teratogen update: Radiation teratogenesis. Teratology 21, 281-298 (1980).
15. K. Muneoka, N. Wanek and S. V. Bryant, Mammalian limb bud development: In situ fate maps of early hindlimb buds. J. Exp. Zool. 249, 50-54 (1989).
16. N. Wanek, K. Muneoka, G. Holler-Dinsmore, R. Burton and S. V. Bryant, A staging system for mouse limb development. J. Exp. Zool. 249, 41-49 (1989).
17. Z. F. Zakeri and H. S. Ahuja, Apoptotic cell death in the limb and its relationship to pattern formation. Biochem. Cell Biol. 72, 603-613 (1994).
18. B. Wang, K. Fujita, C. Ohhira, K. Watanabe, H. Mitani, H. Ohyama, T. Yamada and A. Shima, Radiation induced apoptosis in the mouse limb bud cells in vivo and in vitro. J. Radiat. Res. 37, 369 (1996). [Abstract]
19. G. Konermann, Postimplantation defects in development following ionizing irradiation. Adv. Radiat. Biol. 13, 91-167 (1987).
20. R. M. Winter and C. Tickle, Syndactylies and polydactylies: Embryological overview and suggested classification. Eur. J. Genet. 1, 96-104 (1993).
21. Y. Li, V. G. Sharov, N. Jiang, C. Zaloga, H. N. Sabbah and M. Chopp, Ultrastructural and light microscopic evidence of apoptosis after middle cerebral artery occlusion in the rat. Am. J. Pathol. 146, 1045-1051 (1995).
22. Y. Gavrieli, Y. Sherman and S. A. Ben-Sasson, Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol. 119, 493-501 (1992).
23. A. Kurishita and T. Ihara, Dose-related induction of digital malformation in rats by 5-azacytidine: Description of the defects. Cong. Anom. 29, 59-71 (1989).
24. M. Inouye, Differential staining of cartilage and bone in fetal mouse skeleton by alcian blue and alizarin red S. Cong. Anom. 16, 171-173 (1976).
25. X. Y. Zhou, J. C. Dong, S. Y. Zhou, J. D. Chen and F. R. Guo, Experimental study on relative biological effectiveness of tritium and risk estimates of genetic damage. Chinese Med. J. 102, 872-878 (1989).
26. C. Mon, N. Nakamura, S. Kimura, H. Irie, T. Takigawa and K. Shiota, Programmed cell death in the interdigital tissue of the fetal mouse limb is apoptosis with DNA fragmentation. Anat. Rec. 242, 103-110 (1995).
27. E. J. Ritter, W. J. Scott and J. G. Wilson, Relationship of temporal patterns of the cell death and development to malformations in the rat limb. Possible mechanisms of teratogenesis with inhibitors of DNA synthesis. Teratology 7, 219-226 (1973).
28. W. J. Scott, E. J. Ritter and J. G. Wilson, Delayed appearance of ectodermal cell death as a mechanism of polydactyly induction. J. Embryol. Exp. Morphol. 42, 93-104 (1977).
29. D. Kochhar, J. Penner and J. MacDay, Limb development in mouse embryos. Reduction defects, cytotoxicity and inhibition of DNA synthesis produced by cytosine arabinoside. Teratology 18, 71-92 (1978).
30. S. Kondo, Altruistic cell suicide in relation to radiation hormesis. Int. J. Radiat. Biol. 53, 95-102 (1988).
31. J. H. Hendry, C. S. Potten and A. Merritt, Apoptosis induced by high- and low-LET radiations. Radiat. Environ. Biophys. 34, 59-62 (1995).
32. S. W. Lowe, H. E. Ruley, T. Jacks and D. E. Houseman, P53-dependent apoptosis modulates the cytoxicity of anticancer agents. Cell 74, 957-967 (1993).
33. S. W. Lowe, E. M. Schmitt, S. W. Smith, B. A. Osborne and T. Jacks, p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 362, 847-849 (1993).
34. L. Milas, L. C. Stephens and R. E. Meyn, Relation of apoptosis to cancer therapy. In Vivo 8, 665-674 (1994).
35. A. J. Merritt, C. S. Potten, C. J. Kemp, J. A. Hickman, A. Balmain, D. P. Lane and P. A. Hall, The role of p53 in spontaneous and radiation induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice. Cancer Res. 54, 614-617 (1994).