Sensitivity of quantitative 1H magnetic resonance spectroscopy of the brain in detecting early neuronal damage in systemic lupus erythematosus

Annals of the Rheumatic Diseases

Volumn 60, Issue 2, 2001, Pages 106-111

  Axford, J S ^a   Howe, F A ^a   Heron, C ^a   Griffiths, J R ^b  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^b ST GEORGE S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINE; CREATINE; INOSITOL; N ACETYLASPARTIC ACID;

ADOLESCENT; ADULT; AGED; ARTICLE; BRAIN NERVE CELL; BRAIN TISSUE; BRAIN WATER; CELL DAMAGE; CLINICAL ARTICLE; CLINICAL FEATURE; DISEASE SEVERITY; FEMALE; HUMAN; MALE; NEUROPSYCHIATRY; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SYSTEMIC LUPUS ERYTHEMATOSUS; WHITE MATTER;

ADOLESCENT; ADULT; AGED; ASPARTIC ACID; BRAIN DISEASES; CASE-CONTROL STUDIES; CHOLINE; CREATINE; FEMALE; HUMANS; IMMUNOGLOBULINS, INTRAVENOUS; INOSITOL; LUPUS ERYTHEMATOSUS, SYSTEMIC; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MIDDLE AGED; NORMAL DISTRIBUTION; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX;

EID: 0035132291     PISSN: 00034967     EISSN: None     Source Type: Journal    
DOI: 10.1136/ard.60.2.106     Document Type: Article

References (46)

1. Nene beitrage zur Kenntnis des lupus erythematosus
2. Lymphocyte antigens in neuropsychiatric systemic lupus erythematosus, Relationship of lymphocyte antibody specificities to clinical disease
3. Pathology and pathogenesis of vascular injury in systemic lupus erythematosus
4. Controversies in lupus: Nervous system
5. Neuropsychiatric lupus erythematosus: A 10 year prospective study on the value of diagnostic tests
6. Cognitive impairment in patients with systemic lupus erythematosus
7. Central nervous system involvement in systemic lupus erythematosus: Are we any further forward?
8. Magnetic resonance imaging of central nervous system lesions in patients with lupus erythematosus. Correlation with clinical remission and anti-neurofilament and anti-cardiolipin antibody titres
9. Abnormalities of magnetic resonance imaging of the central nervous system in patients with systemic lupus erythematosus correlate with disease activity
10. Magnetic resonance imaging in systemic lupus erythematosus patients without a history of neuropsychiatric lupus erythematosus
11. Magnetic resonance imaging in the brain in neuropsychiatric systemic lupus erythematosus
12. Lupus anti-coagulant: Correlation with magnetic resonance imaging of brain lesions
13. Analysis of cerebral structural changes in systemic lupus erythematosus by proton MR spectroscopy
14. Magnetic resonance imaging of the brain and cerebral proton spectroscopy in patients with systemic lupus erythematosus
15. Automated single-voxel proton MRS: Technical development and multisite verification
16. Development of the human brain: In vivo quantification of metabolite and water content with proton magnetic resonance spectroscopy
17. Quantitation of proton NMR spectra of the human brain using tissue water as an internal concentration reference
18. 1H NMR data of normal human brain by means of time-domain analysis
19. Quantification of automated single-voxel proton MRS using cerebral water as an internal reference
20. Aging of the adult human brain: In vivo quantification of metabolite content with proton magnetic resonance spectroscopy
21. 31P NMR signals using the variable projection method and prior knowledge
22. In vivo proton spectroscopy in presence of eddy currents
23. SVD-based quantification of magnetic resonance signals
24. 1H MR spectra
25. Continuing ischaemic damage after acute middle cerebral artery infarction in humans demonstrated by short echo proton spectroscopy
26. The 1982 revised criteria for the classification of systemic lupus erythematosus
27. Serial precision of metabolite peak area ratios and water referenced metabolite peak areas in proton MR spectroscopy of the human brain
28. Neurometabolism of active neuropsychiatric lupus determined with proton MR spectroscopy
29. Brain injury and neurometabolic abnormalities in systemic lupus erythematosus
30. Neurometabolite markers of cerebral injury in the antiphospholipid antibody syndrome of systemic lupus erythematosus
31. Relationship between neurometabolite derangement and neurocognitive dysfunction in systemic lupus erythematosus
32. Proton magnetic resonance spectroscopy of systemic lupus erythematosus involving the central nervous system
33. Neurochemistry of brain lesions determined by spectroscopic imaging in systemic lupus erythematosus
34. Spin-spin relaxation of brain tissues in systemic lupus erythmatosus
35. Frontotemporal dementia and early Alzheimer disease: Differentiation with frontal lobe H-1 MR spectroscopy
36. Magnetic resonance spectroscopy of multiple sclerosis: In vivo detection of myelin breakdown products
37. The proton MR spectrum in acute EAE: The significance of the chance in the Cho: Cr-ratio
38. Proton magnetic resonance spectroscopy studies on human brain myo-inositol in hypo-osmolarity and hepatic encephalopathy
39. Human cerebral osmolytes during chronic hyponatremia. A proton magnetic resonance spectroscopy study
40. Absolute concentrations of metabolites in the adult human brain in vivo: Quantification of localised proton MR spectra
41. Brief report: Organic osmolytes in the brain of an infant with hypernatremia
42. Cerebral metabolic disturbances in patients with subacute and chronic diabetes mellitus: Detection with proton MR spectroscopy
43. Biochemical changes in the frontal lobe of HIV-infected individuals detected by magnetic resonance spectroscopy
44. Role of increased cerebral myo-inositol in the dementia of Down syndrome