Postoperative glycyl-glutamine infusion reduces immunosuppression: Partial prevention of the surgery induced decrease in HLA-DR expression on monocytes

Clinical Nutrition

Volumn 20, Issue 1, 2001, Pages 37-42

  Spittler, A ^a   Sautner, T ^a   Gornikiewicz, A ^a   Manhart, N ^a   Oehler, R ^a   Bergmann, M ^a   Fugger R ^a   Roth, E ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Glutamine dipeptide; HLA DR; Infection; Monocyte; Surgery

Indexed keywords

ALANINE; ALANYLGLUTAMINE; AMINO ACID; GLUTAMINE; GLYCINE; GLYCYLGLUTAMINE; HLA DR ANTIGEN; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; NITROGEN; RECEPTOR SUBTYPE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR; VAMIN; VAMIN 14 EF;

ABDOMINAL SURGERY; ADULT; AGE; AGED; AMINO ACID BLOOD LEVEL; ANTIGEN EXPRESSION; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; CLINICAL TRIAL; CONTINUOUS INFUSION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CULTURE MEDIUM; DRUG FORMULATION; FEMALE; FLOW CYTOMETRY; GENDER; HUMAN; HUMAN CELL; HYPOTHESIS; IMMUNE DEFICIENCY; IN VITRO STUDY; INFECTION COMPLICATION; INFECTION SENSITIVITY; INFLAMMATION; INJURY; MAJOR SURGERY; MALE; MONOCYTE; OPERATION DURATION; POSTOPERATIVE PERIOD; PRESERVATION; RANDOMIZED CONTROLLED TRIAL; SEPSIS;

EID: 0035131819     PISSN: 02615614     EISSN: None     Source Type: Journal    
DOI: 10.1054/clnu.2000.0153     Document Type: Article

References (22)

1. Influence of glutamine on the phenotype and function of human monocytes
2. Alterations in the number of circulating leukocytes, phenotype of monocyte and cytokine production in patients undergoing cardiothoracic surgery
3. HLA-DR antigen expression on peripheral blood monocytes correlates with surgical infection
4. Monocyte HLA-DR antigen expression characterizes clinical outcome in the trauma patient
5. Improvement of monocyte function - A new therapeutic approach?
6. Changes in major histocompatibility complex class II expression in monocytes and T cells of patients developing infection after surgery
7. Alanylglutamine reduces muscle loss of alanine and glutamine in postoperative anaesthetized dogs
8. Metabolic disorders in severe abdominal sepsis: Glutamine deficiency in skelet muscle
9. Glutamine and the immune system
10. Safety and efficacy of increasing dosages of glycyl-glutamine for total parenteral nutrition in polytrauma patients
11. Glutamine-containing dipeptides as infusion substrates in the septic state
12. Alanyl-glutamine infusions to patients with acute pancreatitis
13. A diet containing glycine improves survival in endotoxin shock in rat
14. Immunomodulatory effects of glycine on LPS stimulated human blood monocytes: Reduced TNF-α production and accelerated IL-10 expression
15. Glutamin. Wirkunge auf das Immunsystem, auf Eiweiβhaushalt und Darmfunktion
16. Glutamine and the preservation of gut integrity
17. Lymphocyte proliferation modulated by glutamine: Involved in the endogenous redox reaction
18. Clinical and metabolic efficacy of glutamine-supplemented parenteral nutrition after bone marrow transplantation. A randomized, double-blind, controlled study
19. ATP depletion induces an increase in the assembly of a labile pool of polymerized actin in endothelial cells
20. + -ATPase that redistributes to apical membrane during ATP depletion remains functional
21. Influence of molecular structure and plasma hydrolysis on the metabolism of glutamine containing dipeptides in humans
22. Importance of liver and kidney for the utilization of glutamine-containing dipeptides in man