Decreasing ratios of phosphocreatine to β-ATP correlates to progressive acute rejection in a concordant mouse heart to rat xenotransplantation model

Scandinavian Journal of Immunology

Volumn 53, Issue 2, 2001, Pages 171-175

  Lukes, D J ^a,b,c   Madhu, B ^a,b,c   Kjellstrom C ^a,b,c   Gustavsson, M L ^a,b,c   Mjornstedt L ^a,b,c   Olausson, M ^a,b,c   Soussi, B ^a,b,c  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^c ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CREATINE PHOSPHATE; PHOSPHORUS 31;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOENERGY; FEMALE; GRAFT REJECTION; GRAFT SURVIVAL; HEART TRANSPLANTATION; HISTOPATHOLOGY; IMMUNOSUPPRESSIVE TREATMENT; MALE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PREDICTION; PRIORITY JOURNAL; RAT; RATING SCALE; XENOTRANSPLANTATION;

ACUTE DISEASE; ADENOSINE TRIPHOSPHATE; ANIMALS; ENERGY METABOLISM; GRAFT REJECTION; HEART TRANSPLANTATION; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MICE; MICE, INBRED STRAINS; MYOCARDIAL CONTRACTION; MYOCARDIUM; PHOSPHOCREATINE; PHOSPHORUS ISOTOPES; POSTOPERATIVE PERIOD; RATS; RATS, INBRED LEW; TRANSPLANTATION, HETEROLOGOUS; TRANSPLANTATION, HETEROTOPIC;

EID: 0035125967     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3083.2001.00849.x     Document Type: Article

References (27)

1. Cardiac transplantation at the Texas Heart Institute: Comparative analysis of two groups of patients (1968-1969 and 1982-1983)
2. Early phosphorus 31 nuclear magnetic resonance bioenergetic changes potentially predict rejection in heterotopic cardiac allografts
3. Assessment of cardiac rejection by MR-imaging and MR-spectroscopy
4. Correlation of endomyocardial biopsy findings with electrocardiogram voltage in pediatric cardiac allografts
5. Biopsy-induced tricuspid regurgitation after cardiac transplantation
6. MR spectroscopy of the human heart: The status and the challenges
7. In vivo 31P nuclear magnetic resonance findings on heterotopically allografted hearts in rats treated with a novel immunosuppressant, FK506
8. Effect of 15-deoxyspergualin on rejection detected by 31P nuclear magnetic resonance spectroscopy and in vivo mechanisms of action in rat heart transplantation
9. Therapeutic effect of 15-deoxyspergualin on acute graft rejection detected by 31P nuclear magnetic resonance spectrography, and its effect on rat heart transplantation
10. Immunosuppressive effect of a new drug, 15-deoxyspergualin, in heterotopic rat heart transplantation: In vivo energy metabolic studies by 31P-NMR spectroscopy
11. Effect of a new immunosuppressant, 15-deoxyspergualin, on heterotopic rat heart transplantation, in comparison with cyclosporine
12. The detection of chronic heart graft rejection by 31P NMR spectroscopy
13. Xenogeneic transplantation: A review
14. Transplantation of discordant xenografts: A challenge revisited
15. Specific intravenous carbohydrate therapy. A new concept in inhibiting antibody-mediated rejection - Experience with ABO-incompatible cardiac allografting in the baboon
16. A morphological sequential study of mouse-to-rat cardiac xenografts
17. Successful retransplantation of mouse-to-rat cardiac xenografts under immunosuppressive monotherapy with cyclosporine
18. Characteristics of mouse to rat xenograft heart transplantation
19. Role of antibody synthesis and complement activation in concordant xenograft retransplantation
20. Anti-carbohydrate antibodies associated with hyperacute rejection in a vascularized mouse heart-to-rat xenotransplantation model
21. In vivo 31P MRS evaluation of the rejection process and differences in anaesthethic procedures in a concordant xenotransplantation mouse heart to rat model
22. Non-suture organ grafting to the neck vessels in rats
23. Metabolic changes preceding functional and morphologic indices of rejection in heterotopic cardiac allografts
24. Coronary blood flow does not decrease during allograft rejection in heterotopic heart transplants
25. Bioenergetic, functional and morphological consequences of postinfarct cardiac remodeling in the rat
26. Bioenergetic scaling: Metabolic design and body-size constraints in mammals
27. 31P-nuclear magnetic resonance spectroscopy of blood: A species comparison