A morphological sequential study of mouse-to-rat cardiac xenografts

Scandinavian Journal of Immunology

Volumn 48, Issue 5, 1998, Pages 485-490

  Bersztel, A ^a   Tufveson, G ^a   Gannedahl, G ^a   Johnsson, C ^a  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

15 DEOXYSPERGUALIN; BREQUINAR; COMPLEMENT COMPONENT C3; CYCLOPHOSPHAMIDE; CYCLOSPORIN; HEMAGGLUTININ; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; IMMUNOSUPPRESSIVE AGENT; LEFLUNOMIDE; MAJOR HISTOCOMPATIBILITY ANTIGEN; T LYMPHOCYTE ANTIGEN; TACROLIMUS;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY TITER; ARTICLE; CELLULAR IMMUNITY; COMPLEMENT DEPOSITION; GRAFT REJECTION; GRAFT SURVIVAL; HEART MUSCLE FIBROSIS; HEART TRANSPLANTATION; HUMORAL IMMUNITY; IMMUNOGLOBULIN DEPOSITION; IMMUNOHISTOCHEMISTRY; IMMUNOPATHOLOGY; IMMUNOSUPPRESSIVE TREATMENT; INFLAMMATORY INFILTRATE; MACROPHAGE; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MOUSE; NATURAL KILLER CELL MEDIATED CYTOTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; T LYMPHOCYTE SUBPOPULATION; XENOGRAFT;

ANIMALS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HEART TRANSPLANTATION; HEMAGGLUTINATION TESTS; MALE; MICE; RATS; RATS, INBRED LEW; TRANSPLANTATION, HETEROLOGOUS;

EID: 0031764110     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3083.1998.00306.x     Document Type: Article

References (30)

1. Calne RY. Organ transplantation between widely disparate species. Transplant Proc 1970;2:550-6.
2. Van den Bogaerde JB, Aspinall R, Wang MW, Cary N, Lim S, Wright L, White DJ. Induction of long term survival of hamster heart xenografts in rats. Transplantation 1991;52:15-20.
3. Monden M, Valdivia LA, Gotoh M et al. A crucial effect of splenectomy on prolonging cardiac xenograft survival in combination with cyclosporine. Surgery 1989;105:535-42.
4. Marchman W, Araneda D, DeMasi R, Taylor D, Larkin E, Alqaisi M, Thomas F. Prolongation of xenograft survival after combination therapy with 15-deoxyspergualin and total-lymphoid irradiation in the hamster to rat cardiac xenograft model. Transplantation 1992;53:30-4.
5. Rosengard BR, Adachi H, Ueda K et al. Differences in the pathogenesis of first-set allograft rejection and acute xenograft rejection as determined by sequential morphologic analysis. J Heart Transplant 1986;5:263-6.
6. Hasan R, Van den Bogaerde JB, Wallwork J, White DJ. Evidence that long-term survival of concordant xenografts is achieved by inhibition of antispecies antibody production. Transplantation 1992;54:408-13.
7. Gannedahl G, Fellström B, Larsson E, Roos-Engstrand E, Tufveson G. Characteristics of mouse to rat xenograft heart transplantation. Eur Surg Res 1990;22:206-12.
8. Murase N, Starzl TE, Demetris AJ, Valdivia L, Tanabe M, Cramer D, Makowka L. Hamster-to-rat heart and liver xenotransplantation with FK506 plus antiproliferative drugs. Transplantation 1993;55:701-8.
9. Chong AS, Shen J, Xiao F et al. Delayed xenograft rejection in the concordant hamster heart into Lewis rat model. Transplantation 1996;62:90-6.
10. Johnsson C, Andersson A, Bersztel A, Karlsson-Parra A, Gannedahl G, Tufveson G. Successful retransplantation of mouse-to-rat cardiac xenografts under immunosuppressive monotherapy with cyclosporine. Transplantation 1997;63:652-6.
11. National Institutes of Health. Guide for the care and the use of laboratory animals. Bethesda, MA: NIH, 1985:86-123.
12. Hünig T, Wallny H-J, Hartley JK, Lawetzky A, Tiefenthaler G. A monoclonal antibody to a constant determinant of the rat T cell antigen receptor that induces T cell activation. J Exp Med 1969;169:73-86.
13. Brideau RJ, Carter PB, McMaster WR, Mason DW, Williams AF. Two subsets of rat lymphocytes defined with monoclonal antibodies. Eur J Immunol 1980;10:609-15.
14. Chambers WH, Vujanovic NL, DeLeo AB, Olszowy MW, Herberman RB, Hiserodt JC. Monoclonal antibody to a triggering structure expressed on rat natural killer cells and adherent lymphokine activated killer cells. J Exp Med 1989;169:1373-89.
15. Dijkstra CD, Döpp EA, Joling P, Kraal G. The heterogeneity of mononuclear phagocytes in lymphoid organs: distinct macrophage subpopulation in the rat recognised by monoclonal antibodies ED1, ED2 and ED3. Immunology 1985;54:589-99.
16. McMaster WR, Williams AF. Monoclonal antibodies to Ia antigens from rat thymus: cross reactions with mouse and human and use in purification of rat Ia glycoproteins. Immun Rev 1979;47:117-37.
17. Woollett GR, Barclay AN, Puklavec M, Williams AF. Molecular and antigenic heterogeneity of the rat leukocyte-common antigen from thymocytes and T and B lymphocytes. Eur J Immunol 1985;15:168-73.
18. Sternberger L. Immunocytochemistry. New York: Wiley Medical Publications, 1979.
19. Valdivia LA, Monden M, Gotoh M, Nakano Y, Tono T, Mori T. Evidence that deoxyspergualin prevents sensitization and first-set cardiac xenograft rejection in rats by suppression of antibody formation. Transplantation 1990;50:132-6.
20. Fujii H, Takada T, Nemoto K, Abe F, Fujii A, Talmadge JE, Takeuchi T. Deoxyspergualin, a novel immunosuppressant, markedly inhibits human mixed lymphocyte reaction and cytotoxic T-lymphocyte activity in vitro. Int J Immunopharmacol 1992;14:731-7.
21. VanBuskirk AM, DeNagel DC, Guagliardi LE, Brodsky FM, Pierce SK. Cellular and subcellular distribution of PBP72/74, a peptide-binding protein that plays a role in antigen processing. J Immunol 1991;146:500-6.
22. Tepper MA, Nadler S, Mazzucco C, Singh C, Kelley SL. 15-deoxyspergualin, a novel immunosuppressive drug: Studies of the mechanism of action. Ann NY Acad Sci 1993;685:175-92.
23. Kerr PG, Nikolic-Paterson DJ, Lan HY, Tesch G, Rainone S, Atkins R. Deoxyspergualin suppresses local macrophage proliferation in rat renal allograft rejection. Transplantation 1994;58:596-601.
24. Makowka L, Cramer DV. The pathogenesis of xenograft rejection. Clin Transplantation 1994;8:145-54.
25. + macrophage and not a T lymphocyte. Transplantation 1995;60:594-601.
26. Bach FH, Turman MA, Vercellotti GM, Platt JL, Dalmasso AP. Accomondation: a working paradigm for progressing toward clinical discordant xenografting. Transplant Proc 1991;23:205-7.
27. Cramer DV, Wu GD, Chapman FA, Cajulis E, Wang HK, Makowka L. Lymphocytic subsets and histopathologic changes associated with the development of heart transplant arteriosclerosis. J Heart Lung Transplantation 1992;11:458-66.
28. Barclay AN. The localization of populations of lymphocytes defined by monoclonal antibodies in rat lymphoid tissue. Immunology 1981;42:593-600.
29. Fryer JP, Leventhal JR, Dalmasso AP et al. Beyond hyperacute rejection. Transplantation 1995;59:171-6.
30. Lin Y, Vandeputte M, Waer M. Effect of leflunomide and cyclosporine on the occurrence of chronic xenograft lesions. Kidney Int Suppl. 1995;52:S23-8.