Regulation of the urokinase-type plasminogen activator receptor gene in different grades of human glioma cell lines

Clinical Cancer Research

Volumn 7, Issue 2, 2001, Pages 267-276

  Bhattacharya, Anuradha ^a   Lakka, Sajani S ^a   Mohanam, Sanjeeva ^a   Boyd, Douglas ^a   Rao, Jasti S ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

UROKINASE RECEPTOR;

ARTICLE; CANCER CELL; CANCER GRADING; COMPLEX FORMATION; DNA FLANKING REGION; ELECTROPHORETIC MOBILITY; ENZYME ACTIVITY; GENETIC REGULATION; GLIOMA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; MESSENGER RNA SYNTHESIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN LOCALIZATION; RNA STABILITY;

BETA-GALACTOSIDASE; CHLORAMPHENICOL O-ACETYLTRANSFERASE; DICHLORORIBOFURANOSYLBENZIMIDAZOLE; ELECTROPHORESIS, AGAR GEL; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENES, JUN; GLIOMA; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MUTATION; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS C-RAF; RECEPTORS, CELL SURFACE; RNA, MESSENGER; TETRADECANOYLPHORBOL ACETATE; TRANSCRIPTION FACTOR AP-1; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 0035123373     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (51)

1. Purification of zymogen to plasminogen activator from human glioblastoma cells by affinity chromatography with monoclonal antibody
2. The peptide chains of human plasmin. Mechanism of activation of human plasminogen to plasmin
3. Differentiation-enhanced binding of the amino-terminal fragment of human urokinase plasminogen activator to a specific receptor on U937 monocytes
4. r55000 form of the human plasminogen activator, urokinase
5. The ligand-binding domain of the cell surface receptor for urokinase-type plasminogen activator
6. Cellular receptor for urokìnase plasminogen activator. Carboxyl-terminal processing and membrane anchoring by glycosyl-phosphatidylinositol
7. The structure of the urokinase-type plasminogen activator receptor gene
8. Assignment of the human urokinase receptor gene (PLAUR) to 19q13
9. An alternatively spliced variant of mRNA for the human receptor for urokinase plasminogen activator
10. Structure of the human urokinase receptor gene and its similarity to CD59 and the Ly-6 family
11. A conserved TATA-less proximal promoter drives basal transcription from the urokinase-type plasminogen activator receptor gene
12. Regulation of urokinase-type plasminogen activator expression by an ERK1-dependent signaling pathway in a squamous cell carcinoma cell line
13. Identification of a dual specificity kinase that activates the Jun Kinases and p38-Mpk2
14. Selective activation of the JNK signaling cascade and cJun transcriptional activity by the small GT pases rac and cdcH2Hs
15. Differential activation of ERK and JNK mitogen-activated protein kinases by raf-1 and MEKK
16. Tumor necrosis factor α rapidly activates the mitogen-activated protein kinase (MAPK) cascade in a MAPK kinase-dependent. c-Raf-independent fashion in mouse morphages
17. r92.000 type IV collagenase in human brain tumors
18. Cathepsin B expression and localization in glioma progression and invasion
19. Expression and localization of urokinase-type plasminogen activator receptor in human gliomas
20. Up-regulation of urokinase and urokinase receptor genes in malignant astrocytoma
21. Overexpression and localization of cathepsin B during the progression of human gliomas
22. Expression and localization of 72 kDa type IV collagenase (MMP-2) in human malignant gliomas in vivo
23. Expression and localization of urokinase-type plasminogen activator in human astrocytomas in vivo
24. Modulation of in vitro invasion of human glioblastoma cells by urokinase-type plasminogen activator receptor antibody
25. In vitro inhibition of human glioblastoma cell line invasiveness by antisense uPA receptor
26. Inhibition of in vivo tumorigenicity and invasiveness of a human glioblastoma cell line transfected with antisense uPAR vectors
27. Transcriptional activation of the urokinase receptor gene in invasive colon cancer
28. Protein kinase C isoforms in human glioblastoma cells
29. In vitro inhibition of human glioblastoma cell line invasiveness by antisense uPA receptor
30. Type-specific expression of protein kinase C isozymes in CNS tumor cells
31. Extreme instability of myc mRNA in normal and transformed human cells
32. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing principle of proteins binding
33. Molecular aspects of tumor cell invasion and metastasis
34. The urokinase receptor involvement in cell surface proteolysis and cancer invasion
35. Urokinase receptor in human malignant mesothelioma cells: Role in tumor cell mitogenesis and proteolysis
36. c-JUN, JUN B, and JUN D differ in their binding affinities to AP-1 and CRE consensus sequences: Effect of FOS proteins
37. Difference in transcriptional regulatory function between c-Fos and Fra-2
38. Involvement of JunD in transcriptional activation of the orphan receptor gene nur77 by nerve growth factor and membrane depolarization in PC12 cells
39. Integration of MAP kinase signal transduction pathways at the serum response element
40. tcfby MAP kinase stimulates ternary complex formation at c-fos promoter
41. Transcription factor ATF2 regulation by the JNK signal transduction pathway
42. ATFP2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents
43. Transcriptional and post-transcriptional regulation of the receptor for urokinase-type plasminogen activator by cytokines and tumour promoters in the human lung carcinoma cell line A549
44. Hepatocyte growth factor increases urokinase-type plasminogen activator (u-PA) and u-PA receptor expression in Madin-Darby canine kidney epithelial cells
45. Vascular endothelial growth factor increases urokinase receptor expression in vascular endothelial cells
46. Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification
47. Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin
48. Inhibition of epidermal growth factor receptor-associated tyrosine kinase blocks glioblastoma invasion of the brain