Iodide handling by the thyroid epithelial cell

Experimental and Clinical Endocrinology and Diabetes

Volumn 109, Issue 1, 2001, Pages 13-17

  Nilsson, M ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Cell polarity; Efflux; Iodide transport; Iodination; NIS

Indexed keywords

ANTIPORTER; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; SODIUM IODIDE; SODIUM IODIDE SYMPORTER; UNCLASSIFIED DRUG;

CELL POLARITY; EPITHELIUM CELL; HORMONAL REGULATION; HUMAN; HUMAN CELL; INTRACELLULAR TRANSPORT; IODINATION; PATHOPHYSIOLOGY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; SHORT SURVEY; THYROID DISEASE; THYROID HORMONE SYNTHESIS;

CELL MEMBRANE; CELL POLARITY; EPITHELIAL CELLS; HUMANS; IODINE; NA(+)-K(+)-EXCHANGING ATPASE; SYMPORTERS; THYROGLOBULIN; THYROID GLAND; THYROID HORMONES; TIGHT JUNCTIONS;

EID: 0035122462     PISSN: 09477349     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2001-11014     Document Type: Short Survey

References (33)

1. DIDS (4,4′-diisothiocyantostilbene-2,2′-disulfonic acid) increases iodide trapping, inhibits thyroperoxidase and antagonizes the TSH-induced apical iodide efflux in porcine thyroid cells
2. Autoradiographic localization of radio-iodide in the thyroid gland of the mouse
3. Iodide transport in the thyroid gland
4. Tight junctions
5. Expression of pendrin and the Pendred syndrome (PDS) gene in human thyroid tissues
6. Hydrogen peroxide degradation and glutathione peroxidase activity in cultures of thyroid cells
7. Which iodolipids are involved in thyroid autoregulation: Iodolactones or iodoaldehydes?
8. Evidence for extracellularly acting cathepsins mediating thyroid hormone liberation in thyroid epithelial cells
9. Role of tight junctions in establishing and maintaining cell polarity
10. Polarization of thyroid cells in culture. Evidence for the basolateral localization of the "iodide pump" and of the thyroid-stimulating hormone receptor-adenylate cyclase complex
11. Selenium deficiency aggravates the necrotizing effects of a high iodide dose in iodine deficient rats
12. Molecular analysis of the sodium/iodide symporter: Impact on thyroid and extrathyroid pathophysiology
13. Iodine-induced thyroid inhibition and cell necrosis: Two consequences of the same free radical mediated mechanism?
14. Site of iodination in rat thyroid gland deduced from electron microscopic autoradiographs
15. Iodination of thyroglobulin, an intracellular or extracellular process?
16. Localization of iodide binding in the thyroid gland in vitro
17. Biosynthesis of thyroid hormones
18. Glutathione peroxidase degrades intracellular hydrogen peroxide and thereby inhibits intracellular protein iodination in thyroid epithelium
19. Effect of IGF-1 on growth, epithelial barrier and iodide transport in polarized porcine thyrocyte monolayers
20. + uptake on thyroid epithelial cells
21. Thyroidal iodide transport
22. Iodide transport in primary cultured thyroid follicle cells: Evidence of a TSH-regulated channel mediating iodide efflux selectively across the apical domain of the plasma membrane
23. 2+ is polarized
24. Polarized efflux of iodide in porcine thyrocytes occurs via a cAMP-regulated iodide channel in the apical plasma membrane
25. Effects of epidermal growth factor on basolateral iodide uptake and apical iodide permeability in filter-cultured thyroid epithelium
26. Molecular and cellular mechanisms of transepithelial iodide transport in the thyroid
27. Pendrin, the protein encoded by the Pendred syndrome gene (PDS), is an apical porter of iodide in the thyroid and is regulated by thyroglobulin in FRTL-5 cells
28. The Pendred syndrome gene encodes a chloride-iodide transport protein
29. Pendred syndrome maps to chromosome 7q21-34 and is caused by an intrinsic defect in thyroid iodine organification
30. Thyroid iodine transport
31. Transport of iodide and other anions in the thyroid gland
32. Iodide goiter and the pharmacologic effects of excess iodide
33. Thyroid radioiodide transport: Models, rate-limiting steps, and relation to formation of iodoprotein