β-cell adaptation to hyperglycemia

Diabetes

Volumn 50, Issue SUPPL. 1, 2001, Pages

  Laybutt, Ross ^a   Hasenkamp, Wendy ^a   Groff, Adam ^a   Grey, Shane ^a   Jonas, Jean Christophe ^a   Kaneto, Hideaki ^a   Sharma, Arun ^a   Bonner Weir, Susan ^a   Weir, Gordon ^a  

^a JOSLIN DIABETES CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ACYL COENZYME A OXIDASE; CARNITINE PALMITOYLTRANSFERASE; CATALASE; CCAAT ENHANCER BINDING PROTEIN; FAS ANTIGEN; FATTY ACID; FATTY ACID SYNTHASE; GLUTATHIONE PEROXIDASE; HEAT SHOCK PROTEIN 70; HEME OXYGENASE; HEXOKINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; LACTATE DEHYDROGENASE; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; MYC PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PHLORIZIN; PROTEIN BCL 2; PROTEIN P53;

ADAPTATION; ANIMAL CELL; APOPTOSIS; CONFERENCE PAPER; CONTROLLED STUDY; GENE EXPRESSION; HYPERGLYCEMIA; HYPERTROPHY; LIPID OXIDATION; LIPOGENESIS; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PANCREAS RESECTION; PRIORITY JOURNAL; RAT;

EID: 0035122284     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.50.2007.s180     Document Type: Conference Paper

References (5)

1. Chronic hyperglycemia triggers loss of pancreatic beta cell differentiation in an animal model of diabetes
2. Transcription factor abnormalities as a cause of beta cell dysfunction in diabetes: A hypothesis
3. Peroxisome proliferator-activated receptors, orphans with ligands and functions
4. Induction of apoptosis in fibroblasts by c-myc protein
5. Differences in the expression of heat-shock proteins and antioxidant enzymes between human and rodent pancreatic islets: Implications for the pathogenesis of insulin-dependent diabetes mellitus