Identification of a novel, alternatively spliced isoform and single nucleotide polymorphisms in the murine Pea-15 gene

Mammalian Genome

Volumn 12, Issue 2, 2001, Pages 172-174

  Underhill, D Alan ^a   Vogan, Kyle J ^a   Underhill, T Michael ^b   Gros, Philippe ^a  

^a MCGILL UNIVERSITY   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOPROTEIN; RNA;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ARTICLE; ASTROCYTE; CHROMOSOMAL LOCALIZATION; CHROMOSOME 1Q; EMBRYO DEVELOPMENT; GENE OVEREXPRESSION; IN SITU HYBRIDIZATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN PROTEIN INTERACTION; SINGLE NUCLEOTIDE POLYMORPHISM;

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; BASE SEQUENCE; BLOTTING, NORTHERN; EXONS; IN SITU HYBRIDIZATION; INTRONS; MICE; MOLECULAR SEQUENCE DATA; OPEN READING FRAMES; PHOSPHOPROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN ISOFORMS; RNA, MESSENGER;

ANIMALIA; MAMMALIA; MURINAE; PISUM SATIVUM;

EID: 0035121624     PISSN: 09388990     EISSN: None     Source Type: Journal    
DOI: 10.1007/s003350010243     Document Type: Article

References (14)

1. PED/PEA-15 gene controls glucose transport and is overexpressed in type 2 diabetes mellitus
2. PED/PEA-15: An anti-apoptotic molecule that regulates FAS/TNFRI-induced apoptosis
3. Exogenous retinoic acid rapidly induces anterior ectopic expression of murine Hox-2 genes in vivo
4. NMR structure and mutagenesis of the FADD (Mort 1) death-effector domain
5. The major astrocytic phosphoprotein PEA-15 is encoded by two mRNAs conserved on their full length in mouse and human
6. The phosphoprotein protein PEA-15 inhibits Fas- but increases TNF-R1-mediated caspase-8 activity and apoptosis
7. Abnormalities of floor plate, notochord and somite differentiation in the loop-tail (Lp) mouse: A model of severe neural tube defects
8. Assignment of HMATI, the human homolog of the murine mammary transforming gene (MATI) associated with tumorigenesis, to 1q21.1, a region frequently gained in human breast cancers
9. Knock-out of the neural death effector domain protein PEA-15 demonstrates that its expression protects astrocytes from TNFalpha-induced apoptosis
10. FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO- 1) death-inducing signaling complex
11. The death effector domain of Pea-15 is involved in its regulation of integrin activation
12. Hereditary loop-tail in the house mouse
13. Physical delineation of a 700-kb region overlapping the Looptail mutation on mouse chromosome 1
14. Molecular characterization of the human PEA 15 gene on 1q21-q22 and association with type 2 diabetes mellitus in Pima Indians