Multisorbent plasma perfusion in fulminant hepatic failure: Effects of duration and frequency of treatment in rats with grade III hepatic coma

Artificial Organs

Volumn 25, Issue 2, 2001, Pages 109-118

  Ryan, Calvin J ^a   Anilkumar, Thapasimuthu ^a   Ben Hamida, Abdul J A ^a   Khorsandi, Shirin E ^b   Aslam, Mohammed ^b   Pusey, Charles D ^c   Gaylor, John D S ^c   Courtney, James M ^b  

^a Division of Surgery   (United Kingdom)

^b IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

^c UNIVERSITY OF STRATHCLYDE   (United Kingdom)

Author keywords

Endotoxin; Galactosamine; Liver failure; Perfusion; Rat; Regeneration; Support

Indexed keywords

ARTIFICIAL ORGANS; CELL PROLIFERATION; CHARCOAL; GALACTOSAMINE;

CONTRIBUTING FACTOR; ENDOTOXIN; ENDOTOXIN REMOVAL; FAILURE EFFECTS; FULMINANT HEPATIC FAILURES; LIVER CELLS; LIVER FAILURE; PERFUSION; POLYMYXIN B; REGENERATION;

RATS;

ADSORBENT; CHARCOAL; ENDOTOXIN; GALACTOSAMINE; POLYMYXIN B; SEPHAROSE;

ADSORPTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL LIVER; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE COURSE; FEMALE; HEMOPERFUSION; HEPATIC COMA; LIVER FAILURE; LIVER REGENERATION; NONHUMAN; PRIORITY JOURNAL; RAT; SURVIVAL RATE;

ANIMALIA;

EID: 0035116081     PISSN: 0160564X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1525-1594.2001.025002109.x     Document Type: Article

References (51)

1. Classification and clinical syndromes of acute liver failure
2. Fulminant hepatic failure
3. Use of bioartificial and artificial liver support devices
4. Extracorporeal liver support: Historical background and critical analysis
5. Biochemical, haematological and morphological changes in a fulminant hepatic failure rat model for artificial liver assessment
6. Experimental procedures for the assessment of artificial liver support
7. The anti-proliferative effect of plasma from rats with acute fulminant hepatic failure
8. Management of liver failure
9. Activated charcoal haemoperfusion via an extracorporeal circuit in the unrestrained and unanaesthetised rat
10. Repeated membrane plasma separation with on-line sorbent treatment of plasma in the conscious rat
11. Protection from endotoxaemia: A rat model of plasmapheresis and specific adsorption with polymyxin B sulphate
12. Intestinal endotoxin as mediators of hepatic injury: An idea whose time has come again
13. Endotoxin in liver disease: Time for re-appraisal
14. Fulminant hepatic failure: Summary of a workshop
15. Haemoperfusion and DNA synthesis in the rat liver. Part II. Effect of haemoperfusion on DNA synthesis in the rat liver undergoing compensatory hyperplasia after partial hepatectomy
16. Pre-DNA synthesis haemoperfusion
17. Artificial liver support systems: Design of preclinical evaluation programmes
18. Transference of hepatic coma to normal rats from galactosamine treated donors by reverse plasma exchange
19. Experimental models of plasma perfusion
20. Significance of endotoxaemia in experimental galactosamine hepatitis in rats
21. On the pathogenesis of galactosamine hepatitis in rats
22. Experimental hepatitis induced by D-galactosamine
23. Controlled trials of charcoal haemoperfusion and prognostic factors in fulminant hepatic failure
24. Liver regeneration in relationship to acute liver failure
25. Auxiliary liver transplantation: Regeneration of the native liver and outcome in 30 patients with fulminant hepatic failure: A multicenter European study
26. Liver regeneration in fulminant hepatitis as evaluated by serum transforming growth factor alpha levels
27. Hepatocyte replication and liver regeneration
28. Interleukin-1B is a potent growth inhibitor of adult rat hepatocytes in primary culture
29. Effect of hepatic failure toxins on regenerative enzymes in the liver after injury with galactosamine in the rat
30. Inhibition of hepatic DNA synthesis in fulminant hepatic failure
31. Humoral inhibitor of rat hepatocyte DNA synthesis from patients with fulminant hepatic failure
32. Fulminant hepatic failure
33. Management of infection in acute liver failure
34. Clinical effects of a sorbent suspension dialysis system in the treatment of hepatic coma (the Biologic-DT)
35. Dialysis against a recycled albumin solution enables the removal of albumin-bound toxins
36. Evaluation of the BioLogic-DT sorbent-suspension dialyser in patients with fulminant hepatic failure
37. The microspheres based detoxification system (MDS). A new extracorporeal blood purification procedure based on recirculated microspherical adsorbent particles
38. Microspheres based detoxification system: A new method in convective blood purification
39. Push-pull sorbent based pheresis for treatment of acute hepatic failure: The BioLogic-detoxifier/plasma filter system
40. Cytokines and endotoxin removal by sorbents and its application in push-pull sorbent-based pheresis: The BioLogic-DTPF system
41. Molecular adsorbent recycling system (MARS): Clinical results of a new membrane-based blood purification system for bioartificial liver
42. Development of a hybrid bioartificial liver
43. Clinical experience with an extracorporeal liver assist device
44. Hepatocyte culture and bioreactor design for liver support systems
45. Bioartificial liver support system using porcine hepatocytes entrapped in a three-dimensional hollow fiber module with collagen gel: An evaluation in the swine acute liver failure model
46. Evidence of absence of porcine endogenous retrovirus (PERV) infection in patients treated with a bioartificial liver support system
47. Cellular component of bioartificial liver support systems
48. In vivo efficacy of a bioartificial liver in improving recovery from fulminant hepatic failure: A controlled study in pigs