Unfolding of titin domains explains the viscoelastic behavior of skeletal myofibrils

Biophysical Journal

Volumn 80, Issue 3, 2001, Pages 1442-1451

  Minajeva, Ave ^a,c   Kulke, Michael ^a   Fernandez, Julio M ^b   Linke, Wolfgang A ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b MAYO CLINIC   (United States)

^c UNIVERSITY OF TARTU   (Estonia)

Author keywords

[No Author keywords available]

Indexed keywords

CONNECTIN;

ANIMAL TISSUE; ARTICLE; HYSTERESIS; MECHANICS; MUSCLE FIBRIL; MUSCLE STRETCHING; NONHUMAN; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FOLDING; PSOAS MUSCLE; RAT; SARCOMERE; VISCOELASTICITY;

ANIMALIA;

EID: 0035115798     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(01)76116-4     Document Type: Article

References (10)

1. Bartoo, M. L., W. A. Linke, and G. H. Pollack. 1997. Basis of passive tension and stiffness in isolated rabbit myofibrils. Am. J. Physiol. 273: C266-C276.
2. Bennett, P. M., T. E. Hodkin, and C. Hawkins. 1997. Evidence that the tandem Ig domains near the end of the muscle thick filament form an inelastic part of the I-band titin. J. Struct. Biol. 120:93-104.
3. Brenner, B., M. Schoenberg, J. M. Chalovich, L. E. Greene, and E. Eisenberg. 1982. Evidence for cross-bridge attachment in relaxed muscle at low ionic strength. Proc. Natl. Acad. Sci. U.S.A. 79:7288-7291.
4. Carrion-Vazquez, M., A. F. Oberhauser, S. B. Fowler, P. E. Marszalek, S. E. Broedel, J. Clarke, and J. M. Fernandez. 1999. Mechanical and chemical unfolding of a single protein: a comparison. Proc. Natl. Acad. Sci. U.S.A. 96:3694-3699.
5. Erickson, H. P. 1994. Reversible unfolding of fibronectin type III and immunoglobulin domains provides the structural basis for stretch and elasticity of titin and fibronectin. Proc. Natl. Acad. Sci. U.S.A. 91:10114-10118.
6. Fisher, T. E., A. F. Oberhauser, M. Carrion-Vazquez, P. E. Marszalek, and J. M. Fernandez. 1999. The study of protein mechanics with the atomic force microscope. Trends Biol. Sci. 24:379-384.
7. Freiburg, A., K. Trombitas, W. Hell, O. Cazorla, F. Fougerousse, T. Centner, B. Kolmerer, C. Witt, J. S. Beckmann, C. C. Gregorio, H. Granzier, and S. Labeit. 2000. Series of exon-skipping events in the elastic spring region of titin as the structural basis for myofibrillar elastic diversity. Circ. Res. 86:1114-1121.
8. Fürst, D. O., M. Osborn, R. Nave, and K. Weber. 1988. The organization of titin filaments in the half-sarcomere revealed by monoclonal antibodies in immunoelectron microscopy: a map of ten nonrepetitive epitopes starting at the Z-line extends close to the M-line. J. Cell Biol. 106:1563-1572.
9. Gautel, M., and D. Goulding. 1996. A molecular map of titin/connectin elasticity reveals two different mechanisms acting in series. FEBS Lett. 385:11-14.
10. Gautel, M., E. Lehtonen, and F. Pietruschka. 1996. Assembly of the cardiac I-band region of titin/connectin: expression of the cardiac-specific regions and their relation to the elastic segments. J. Muscle Res. Cell Motil. 17:449-461.