Innate and acquired resistance to African trypanosomiasis

Journal of Parasitology

Volumn 87, Issue 1, 2001, Pages 1-9

  Black, S J ^a   Seed, J R ^a   Murphy, N B ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN A; APOLIPOPROTEIN C; LOW DENSITY LIPOPROTEIN RECEPTOR;

AFRICAN TRYPANOSOMIASIS; ANIMAL PARASITOSIS; DISEASE CONTROL; DISEASE PREDISPOSITION; DISEASE TRANSMISSION; HOST SUSCEPTIBILITY; HUMORAL IMMUNITY; IMMUNITY; IMMUNIZATION; INFECTION RESISTANCE; NONHUMAN; PARASITISM; REVIEW; TRYPANOSOMA; TSETSE FLY;

ANIMALIA; BOS TAURUS; BOVINAE; BUBALUS; GLOSSINA (PROPER); PROTOZOA; SYNCERUS CAFFER CAFFER; TRYPANOSOMA;

EID: 0035114596     PISSN: 00223395     EISSN: None     Source Type: Journal    
DOI: 10.1645/0022-3395(2001)087[0001:iaarta]2.0.co;2     Document Type: Review

References (115)

1. Isolation of drug-resistant strains of Trypanosoma congolense from the lower Shabelle region of southern Somalia
2. Susceptibility and immune responses of zebu and taurine cattle of West Africa to infection with Trypanosoma congolense transmitted by Glossina morsitans centralis
3. Trypanosoma congolense: Susceptibility of cattle to cyclical challenge
4. Transcription of 'inactive' expression sites in African trypanosomes leads to expression of multiple transferrin receptor RNA's in bloodstream forms
5. The importance of African wild animals as reservoirs of trypanosomiasis
6. The experimental infection of some African wild animals with Trypanosoma rhodesiense, T. brucei and T. congolense
7. Therapy of human African trypanosomiasis: Current situation
8. Trypanosomosis and trypanotolerance in cattle: A role for congopain?
9. Antibody responses to a 33 kDa cysteine protease of Trypanosoma congolense: Relationship to 'trypanotolerance' in cattle
10. Antibody responses to invariant antigens of Trypanosoma congolense in cattle of differing susceptibility to trypanosomiasis
11. The pellicle and the membrane of the flagellum, flagellar adhesion zone, and flagellar pocket: Functionally discrete surface domains of the bloodstream form of African trypanosomes
12. The biochemical basis of arsenical-diamidine cross-resistance in African trypanosomes
13. A new method for the isolation of the trypanocidal factor from normal human serum
14. r 145000 low-density lipoproteins (LDL)-binding protein conserved throughout the Kinetoplastida order
15. Mitochondrial development in Trypanosoma brucei brucei transitional bloodstream forms
16. The role of transferrin-receptor variation in the host range of Trypanosoma brucei
17. Serum lipoproteins are required for multiplication of Trypanosoma brucei brucei under axenic culture conditions
18. Anti-Trypanosoma brucei activity of nonprimate zoo sera
19. Control of VSG gene expression sites in Trypanosoma brucei
20. The expression sites for variant surface glycoproteins of Trypanosoma brucei
21. Surface receptors and transporters of Trypanosoma brucei
22. Mitochondrial diversity and the origins of African and European cattle
23. Therapeutic effect of Berenil and Samorin in mice infected with four trypanosome populations isolated from Zambian cattle
24. Receptors for the host low-density lipoproteins on the hemoflagellate Trypanosoma brucei: Purification and involvement in the growth of the parasite
25. Role of acidic compartments in Trypanosoma brucei, with special reference to low-density lipoprotein processing
26. Host plasma low-density lipoprotein particles as an essential source of lipids for the blood-stream forms of Trypanosoma brucei
27. The enzymes of the classical pentose phosphate pathway display differential activities in procyclic and bloodstream forms of Trypanosoma brucei
28. Regulation of VSG expression site transcription and switching in Trypanosoma brucei
29. A gene expressed only in serum-resistant variants of Trypanosoma brucei rhodesiense
30. 2+ is an essential cofactor for trypanocidal activity of normal human serum
31. Comparative studies on N'Dama and zebu cattle following repeated infections with Trypanosoma congolense
32. Susceptibility of buffaloes, cattle and goats to infection with different stocks of Trypanosoma vivax transmitted by Glossina morsitans centralis
33. Metabolism and functions of trypanothione in the Kinetoplastida
34. Purine metabolism in the bloodstream forms of Trypanosoma gambiense and Trypanosoma rhodesiense
35. Glutathione and trypanothione in parasitic hydroperoxide metabolism
36. Sleeping sickness survey in Musoma district, Tanzania
37. Trypanosoma brucei brucei obtains cholesterol from plasma lipoproteins
38. Comparison of the cytolytic effects in vitro on Trypanosoma brucei brucei of plasma, high density lipoproteins, and apolipoprotein A-I from hosts both susceptible (cattle and sheep) and resistant (human and baboon) to infection
39. Characteristics of the binding of human and bovine high-density lipoproteins by bloodstream forms of the African trypanosome, Trypanosoma brucei brucei
40. Susceptibility of African buffalo and Boran cattle to Trypanosoma congolense transmitted by Glossina morsitans centralis
41. Mechanism of resistance of African trypanosomes to cytotoxic human HDL
42. Endocytosis of a cytotoxic human high density lipoprotein results in disruption of acidic intracellular vesicles and subsequent killing of African trypanosomes
43. Lysis of Trypanosoma brucei by a toxic subspecies of human high density lipoprotein
44. Geographic distribution and frequency of a taurine Bos taurus and an indicine Bos indicus Y specific allele amongst sub-Saharan African cattle breeds
45. Alterations in ornithine decarboxylase characteristics accounts for tolerance of Trypanosoma brucei rhodesiense to D,L,-alpha-difluoromethylornithine
46. Differences between N'Dama and Boran cattle in the ability of their peripheral blood leukocytes to bind antibody-coated trypanosomes
47. Localization of genes controlling resistance to trypanosomiasis in mice
48. Campaign against sleeping sickness in South-West Uganda by trapping tsetse flies
49. Therapeutic failure of melarsopol among patients treated for late stage T. b. gambiense human trypanosomiasis in Uganda
50. Heterogeneity in the properties of the trypanolytic factor in normal human serum
51. Trypanosomes, tsetse and trypanotolerance: Coevolution in tropical Africa
52. Expression and localization of serum resistance associated protein in Trypanosoma brucei rhodesiense
53. Partial protection against natural trypanosomiasis after vaccination with a flagellar pocket antigen from Trypanosoma brucei rhodesiense
54. Multiple drug-resistant bovine trypanosomes in South Darfur Province, Sudan
55. The requirements for G1 checkpoint progression of Trypanosoma brucei S 427 clone 1
56. Control of G1 to S cell cycle progression of Trypanosoma brucei S 427 organisms under axenic culture conditions
57. How do African game animals control trypanosome infections?
58. Characterization of the human serum trypanosome toxin, haptoglobin-related protein
59. The trypanocidal Cape buffalo serum protein is xanthine oxidase
60. Trypanotolerance in cattle and prospects for the control of trypanosomiasis by selective breeding
61. Molecular variation in trypanosomes
62. Linear poly-n-acetyl-lactosamine as sorting signals in exo/endocytosis in Trypanosome brucei
63. A flagellar pocket membrane fraction from Trypanosoma brucei rhodesiense: Immunogold localization and nonvariant immunoprotection
64. Susceptibility of African buffalo and Boran cattle to intravenous inoculation with Trypanosoma congolense bloodstream forms
65. The removal of trypanolytic activity from human serum by Trypanosoma brucei gambiense and its subsequent recovery in trypanosome lysates
66. Potential of trypanotolerance as a contribution to sustainable livestock production in tsetse affected Africa
67. Susceptibility of N'Dama and Boran catte to sequential challenges with tsetse-transmitted clones of Trypanosoma congolense
68. Susceptibility of N'Dama and Boran cattle to tsetse-transmitted primary and rechallenge infections with a homologous serodeme of Trypanosoma congolense
69. Expression and function of surface proteins in Trypanosoma brucei
70. Experimental immunity against trypanosomiasis
71. Experimental immunity against trypanosomiasis in rabbits
72. Experimental immunity against trypanosomiasis in sheep
73. Characterization of a novel trypanosome lyric factor from human serum
74. The main lytic factor of Trypanosoma brucei brucei in normal human serum is not high density lipoprotein
75. African buffalo serum contains novel trypanocidal protein
76. The blood incubation infectivity test: A simple test which may serve to distinguish Trypanosoma brucei from T. rhodesiense
77. Identification of the trypanocidal factor in normal human serum: High density lipoprotein
78. Trypanosoma brucei: Biochemical and morphological studies of cytotoxicity caused by normal human serum
79. Role of phospholipids in the cytotoxic action of high density lipoprotein on trypanosomes
80. Trypanosoma brucei: Cytotoxicity of host high-density lipoprotein is not mediated by apolipoprotein A-I
81. The effect of human serum in vitro on Trypanosoma (Trypanozoon) brucei species trypanosomes and its relationship to infectivity in the blood incubation infectivity test
82. Identification and selection of cattle naturally resistant to African trypanosomiasis
83. Immune effector mechanisms involved in the control of parasitemia in Trypanosoma brucei-infected wildebeest (Connochaetes taurinus)
84. A novel heterodimeric transferrin receptor encoded by a pair of VSG expression site-associated genes in T. brucei
85. Transferrin is a growth factor for the bloodstream form of Trypanosoma brucei
86. A survey for a trypanocidal factor in primate sera
87. Relationship between human serum trypanocidal activity and host resistance to African trypanosomes
88. Failure of immunization with Trypanosome endocytotic vesicle membrane proteins to provide nonvariant immunoprotection against Trypanosome brucei
89. Killing of trypanosomes by the human haptoglobin-related protein
90. Identification of haptoglobin as a natural inhibitor of trypanocidal activity in human serum
91. Evidence for widespread asymptomatic Trypanosoma rhodesiense human infection in the Luangwa Valley (Zambia)
92. Subcellular fractionation of Trypanosoma brucei bloodstream forms with special reference to hydrolases
93. Bloodstream forms of Trypanosoma brucei require only small amounts of iron for growth
94. Transferrin-binding protein complex is the receptor for transferrin uptake in Trypanosoma brucei
95. Immune responses of cattle to African trypanosomes: Protective or pathogenic?
96. Trypanosoma congolense: B-lymphocyte responses differ between trypanotolerant and trypanosusceptible cattle
97. Haptoglobin-related protein and apolipoprotein A1 are components of the two trypanolytic factors in human serum
98. Localization of acid phosphatase activity on the surface of blood-stream forms of Trypanosoma congolense
99. High frequency of antigenic variation in Trypanosoma brucei rhodesiense infections
100. Reconstitution of the trypanolytic factor from components of a subspecies of human high-density lipoproteins
101. Development of baits for tsetse flies (Diptera: Glossinidae) in Zimbabwe
102. Serum lipoprotein and Trypanosoma brucei brucei interactions in vitro
103. Selective inhibition of the uptake by blood-stream form Trypanosoma brucei brucei of serum lipoprotein-associated phospholipid and cholesteryl ester
104. Evaluation of variant specific trypanolysis tests for serodiagnosis of human infections with Trypanosoma brucei gambiense
105. Subcellular distribution of adenylate cyclase, cyclic-AMP phosphodiesterase, protein kinases and phosphoprotein phosphatase in Trypanosoma brucei
106. Purine requirements for the expression of Cape buffalo serum trypanocidal activity
107. Infection-associated decline of Cape buffalo blood catalase augments serum trypanocidal activity
108. Natural and acquired resistance to Trypanosoma vivax in cattle
109. Control and surveillance of African trypanosomiasis
110. The role of anti-variable surface glycoprotein antibody responses in bovine trypanotolerance
111. A VSG expression site-associated gene confers resistance to human serum in Trypanosoma rhodesiense
112. Molecular characterization of two invariant surface glycoproteins specific for the bloodstream stage of Trypanosoma brucei