Experimental study of treatment of acute liver failure with bioartificial liver in pigs

World Chinese Journal of Digestology

Volumn 9, Issue 2, 2001, Pages 139-143

  Huan Zhang Hu, ^a   Xiao Ping Xu, ^a   Gao, Y ^a   Ji Zhen Yang, ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Animals, laboratory; Bioartifical liver; Liver failure, acute therapy; Micro capsulized activated carbon adsorbing; Porcine hepatocytes; Swine

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBUMIN; AMMONIA; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; BIOCHEMICAL MARKER; CREATINE; FIBRINOGEN; NITROGEN; PROTHROMBIN; UREA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ARTIFICIAL LIVER; CONTROLLED STUDY; LIVER FAILURE; LIVER FUNCTION TEST; LIVER PERFUSION; NONHUMAN; SURVIVAL TIME; SWINE;

EID: 0035114244     PISSN: 10093079     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (48)

1. Fulminant hepatic failure
2. Fulminant hepatic failure: Summary of a workshop
3. Acute liver failure: A progress report
4. Recent advances in the application of cultured hepatocytes into bioartificial liver
5. Liver transplantation for fulminant and subacute viral hepatic failure in adults
6. Update on liver transplantation
7. Bio-artificial liver from cultured human foetal hepatocytes: Feasibility and prospects
8. Extracorporeal liver support systems
9. Alternatives to liver transplantation: From hepatocyte transplantation to tissue-engineered organs
10. Bioartificial liver
11. Review article: The management of acute liver failure
12. What should we expect from a bioartificial liver in fulminant hepatic failure?
13. Liver transplantation. Current aspects
14. The bioartificial liver: State of the art
15. Alternatives to liver transplantation
16. Extracorporeal liver support: Application to fulminant hepatic failure
17. Regulation of liver growth: Protooncogents and transforming growth factors
18. Cultivation of human liver cell lines with microcarriers acting as biological materials of bioartificial liver
19. Cultivation of immortalized human hepatocytes HepZ on macroporous CultiSpher G microcarriers
20. Positive biochemical effects of a bioartificial liver support system (BALSS) in a porcine fulminant hepatic failure (FHF) model
21. Multiporous cellulose microcarrier for the development of a hybrid artificial liver using isolated hepatocytes
22. Hepatocytes in cell therapy
23. Effectiveness of fructose-modified chitosan as a scaffold for hepatocyte attachment
24. Cell-based therapy of acute liver failure: The extracorporeal bioartificial liver
25. In vitro morphological and functional characterization of isolated porcine hepatocytes for extracorporeal liver support: Bile acid uptake and conjugation
26. Selected aspects of the microencapsulation of mammalian cells in HEMA-MMA
27. Cytoprotective influence of ZVAD-fmk and glycine on gel-entrapped rat hepatocytes in a bioartificial liver
28. Bioartificial liver support system using porcine hepatocytes entrapped in a three-dimensional hollow fiber module with collagen gel: An evaluation in the swine acute liver failure model
29. Bioartificial liver treatment in rats with fulminant hepatic failure: Effect on DNA-binding activity of liver-enriched and growth-associated transcription factors
30. Apoptosis by gel-entrapped hepatocytes in a bioartificial liver
31. Maintained function of primary human hepatocytes by cellular interactions in coculture: Implications for liver support systems
32. Immunoisolation of hybrid liver support systems by semipermeable membranes
33. Oxygen transfer in a diffusion-limited hollow fiber bioartificial liver
34. In vitro evaluation of metabolic functions of a bioartificial liver
35. Novel bioartificial liver support system: Preclinical evaluation
36. Oxygen delivery to and use by primary porcine hepatocytes in the Hepat Assist 2000 system for extracorporeal treatment of patients in endstage liver failure
37. Comparisons of porcine hepatocyte spheroids and single hepatocytes in the non-woven fabric bioartificial liver module
38. In vitro function of porcine hepatocyte spheroids in 100% human plasma
39. A morphologic study of regeneration of the liver after partial removal
40. Hepatocyte function in a hollow fiber bioreactor: A potential bioartificial liver
41. Development of a hollow-fiber module inoculated with liver cells
42. Clinical experience with a bioartificial liver in the treatment of severe liver failure: A phase I clinical trial
43. Artificial liver: Review and Cedars-Sinai experience
44. Commercially available media for flushing extracorporeal bioartificial liver systems prior to connection to the patient's circulation: An in vitro comparative study in two and three dimensional porcine hepatocyte cultures
45. Numerical model of fluid flow and oxygen transport in a radial-flow microchannel containing hepatocytes
46. Evaluation of a novel bioartificial liver in rats with complete liver ischemia: Treatment efficacy and species-specific alpha-GST detection to monitor hepatocyte viability
47. Assessment of an extracorporeal liver assist device in anhepatic dogs
48. Characterization of human xenoreactive antibodies in liver failure patients exposed to pig hepatocytes after bioartificial liver treatment: An ex vivo model of pig to human xenotransplantation