Methylene blue reduces lung fluid filtration during the early phase of endotoxemia in awake sheep

Critical Care Medicine

Volumn 29, Issue 2, 2001, Pages 374-379

  Evgenov, Oleg V ^a   Sager, Georg ^a   Bjertnaes, Lars J ^a  

^a UNIVERSITY OF TROMSØ   (Norway)

Author keywords

Acute lung injury; Capillary permeability; Cyclic nucleotides; Endotoxin; Lung fluid filtration; Lung lymph flow; Methylene blue; Nitric oxide; Pulmonary circulation; Sheep

Indexed keywords

CYCLIC GMP; ENDOTOXIN; METHYLENE BLUE;

ANIMAL EXPERIMENT; ARTICLE; CAPILLARY PERMEABILITY; CONTROLLED STUDY; DRUG EFFECT; ENDOTOXEMIA; ESCHERICHIA COLI; FEMALE; FILTRATION; LUNG CAPILLARY PRESSURE; LUNG CLEARANCE; LUNG FLUID; LUNG INJURY; LUNG LYMPH FLOW; LUNG VASCULAR RESISTANCE; MALE; NONHUMAN; PRIORITY JOURNAL; SHEEP; WAKEFULNESS;

EID: 0035112950     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-200102000-00028     Document Type: Article

References (34)

1. Increased sheep lung vascular permeability caused by Escherichia coli endotoxin
2. Effects of endotoxemia on cyclic nucleotides in the unanesthetized sheep
3. Pulmonary injury and prostaglandin production during endotoxemia in conscious sheep
4. Nitric oxide: Physiology, pathophysiology, and pharmacology
5. Relationship between cyclic guanosine 3′:5′-monophosphate formation and relaxation of coronary arterial smooth muscle by glyceryl trinitrate, nitroprusside, nitrite and nitric oxide: Effects of methylene blue and methemoglobin
6. Alterations in nitric oxide production in various forms of circulatory shock
7. Endothelial barrier dysfunction and oxidative stress: Roles for nitric oxide?
8. Beneficial versus detrimental effects of nitric oxide synthase inhibitors in circulatory shock: Lessons learned from experimental and clinical studies
9. cGMP and nitric oxide modulate thrombin-induced endothelial permeability. Regulation via different pathways in human aortic and umbilical vein endothelial cells
10. Inhaled nitric oxide reduces lung fluid filtration after endotoxin in awake sheep
11. Inhibition of nitric oxide synthesis by methylene blue
12. Methylene blue reverses endotoxin-induced hypotension
13. Effects of methylene blue on oxygen availability and regional blood flow during endotoxic shock
14. Methylene blue increases systemic vascular resistance in human septic shock
15. Methylene blue increases myocardial function in septic shock
16. Methylene blue administration in septic shock: A clinical trial
17. Methylene blue - A promising treatment modality in sepsis induced by bowel perforation
18. Preparation of chronic lung lymph fistulas in sheep
19. Estimation of effective pulmonary capillary pressure in intact lungs
20. Analysis of lymphatic protein flux data. I. Estimation of the reflection coefficient and permeability surface area product for total protein
21. Cell density-dependence of cAMP and cGMP levels in four human cell lines derived from carcinomas of the uterine cervix
22. 15N]nitrate in biological fluids
23. Differential effects of prolonged septicemia on isolated pulmonary arteries and veins from sheep
24. Effects of endotoxemia on the sheep lung microvascular membrane: A two-pore theory
25. Effect of aminoguanidine on lung fluid filtration after endotoxin in awake sheep
26. Nitric oxide production by lymphatic endothelial cells in vitro
27. Nitric oxide and endothelium-dependent relaxation in tracheobronchial lymph vessels
28. Role of cyclic adenosine monophosphate in the induction of endothelial barrier properties
29. Early post-treatment with pentoxifylline or dibutyryl cAMP attenuates Escherichia coli-induced acute lung injury in guinea pigs
30. Effects of dibutyryl cAMP on pulmonary air embolism-induced lung injury in awake sheep
31. Methylene blue but not changes in cyclic GMP inhibits resting and bradykinin-stimulated production of prostacyclin by pig aortic endothelial cells
32. Regulation of the inducible cyclo-oxygenase pathway in human cultured airway epithelial (A549) cells by nitric oxide
33. Fever: An integrated response of the central nervous system to oxidative stress
34. Intravascular macrophage depletion attenuates endotoxin lung injury in anesthetized sheep