Down's syndrome fibroblasts anticipate the accumulation of specific ageing-related mtDNA mutations [4]

Annals of Neurology

Volumn 49, Issue 1, 2001, Pages 137-138

  Bo, Roberto Del ^a,b   Comi, Giacomo Pietro ^a   Perini, Maria Paola ^a   Strazzer, Sandra ^a   Bresolin, Nereo ^a   Scarlato, Guglielmo ^a  

^a FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

^b SCIENTIFIC INSTITUTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

MITOCHONDRIAL DNA;

ADOLESCENT; ADULT; AGED; AGING; ALZHEIMER DISEASE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN SYNDROME; GENE MUTATION; HUMAN; HUMAN CELL; LETTER; MITOCHONDRION; NEUROPATHOLOGY; POINT MUTATION; PRIORITY JOURNAL; SKIN FIBROBLAST;

AGED; AGING; DNA, MITOCHONDRIAL; DOWN SYNDROME; FIBROBLASTS; HUMANS; MIDDLE AGED; MUTATION;

EID: 0035112489     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/1531-8249(200101)49:1<137::AID-ANA26>3.0.CO;2-I     Document Type: Letter

References (5)

1. Down's syndrome and the links with Alzheimer's disease
2. Mitochondrial enzyme deficiencies in Down's syndrome
3. Oxidative damage and mitochondrial decay in aging
4. Aging, energy and oxidative stress in neurodegenerative diseases
5. Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication