Interactions of bacterial lipopolysaccharide and peptidoglycan with a 70 kDa and an 80 kDa protein on the cell surface of CD14+ and CD14- cells

Human Immunology

Volumn 62, Issue 1, 2001, Pages 50-63

  Triantafilou, Kathy ^a   Triantafilou, Martha ^a   Dedrick, Russell L ^b  

^a UNIVERSITY OF ESSEX   (United Kingdom)

^b XOMA Corporation   (United States)

Author keywords

Biochemistry; Endothelial cells; Endotoxin shock; Human; Infectious immunity bacteria; Lipopolysaccharide

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CD14 ANTIGEN; CELL SURFACE PROTEIN; GLYCOSYLPHOSPHATIDYLINOSITOL; LIPOPOLYSACCHARIDE BINDING PROTEIN; LIPOPOLYSACCHARIDE LIPOTEICHOIC ACID ASSOCIATED PROTEIN 1; LIPOPOLYSACCHARIDE LIPOTEICHOIC ACID ASSOCIATED PROTEIN 2; LIPOTEICHOIC ACID; MEMBRANE ANTIGEN; PEPTIDOGLYCAN; PLASMA PROTEIN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; BACTERIAL CELL WALL; CELL STIMULATION; CONTROLLED STUDY; GRAM POSITIVE BACTERIUM; HUMAN; HUMAN CELL; NONHUMAN; PRECIPITATION; PRIORITY JOURNAL; PROTEIN BINDING; SEPTIC SHOCK; SIGNAL TRANSDUCTION;

ACUTE-PHASE PROTEINS; ANIMALS; ANTIGENS, CD14; BACTERIAL PROTEINS; CARRIER PROTEINS; CELL LINE; CELLS, CULTURED; CHO CELLS; CRICETINAE; HUMANS; LIPOPOLYSACCHARIDES; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MOLECULAR WEIGHT; MUTATION; PEPTIDOGLYCAN; PRECIPITIN TESTS; RECEPTORS, CELL SURFACE; SOLUBILITY; TEICHOIC ACIDS; TRANSFECTION;

EID: 0035110435     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0198-8859(00)00222-6     Document Type: Article

References (35)

1. Soluble peptidoglycan-induced cytokine production can be blocked by anti-CD14 monoclonal-antibodies and by lipid-a partial structures
2. CD14 is a cell-activating receptor for bacterial peptidoglycan
3. CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding-protein
4. Structure and function of lipopolysaccharide binding protein
5. Isolation of a lipopolysaccharide-binding acute phase reactant from rabbit serum
6. Receptor-mediated mechanisms of cell stimulation by bacterial endotoxin
7. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
8. A family of human receptors structurally related to Drosophila Toll
9. Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction
10. Human Toll-like receptor 2 confers responsiveness to bacterial lipopolyssacharide
11. Endotoxin-tolerant mice have mutations in toll-like receptor 4 (TLR4)
12. Defective LPS signaling in C3H/Hej and C57BL/10ScCr mice: Mutations in TLR4 gene
13. Toll-like receptor-2 mediates lipopolysaccharide-included cellular signalling
14. Cutting edge: Toll-like receptor 4 (TLR4) deficient mice are hyporesponsive to lipopolysaccharide. Evidence for TLR4 as the LPS gene product
15. Soluble CD14 participates in the response of cells to lipopolysaccharide
16. Lipopolysaccharide-soluble CD14 complexes activate human endothelial and epithelial-cells
17. Release from a human monocyte-like cell line of two different soluble forms of the lipopolysaccharide receptor, CD14
18. Lipopolysaccharide activation of human endothelial and epithelial cells is mediated by lipopolysaccharide-binding protein and soluble CD14
19. Glycosyl-phosphatidylinositol-anchored or integral membrane forms of CD14 mediate identical cellular-responses to endotoxin
20. Response of neutrophils to LPS. Different signalling pathways for CD18 mediated adhesion and Fc-mediated phagocytosis
21. Identification of lipopolysaccharide binding proteins in 70Z/3 cells by photoaffinity ctosslinking
22. Peptidoglycan and lipopolysaccharide bind to the same binding site on lymphocytes
23. Lipopolysaccharide (LPS) binding to 73 kDa and 35 kDa surface proteins on lymphoreticular cells: Preferential inhibition of LPS binding to the former by Rhodopseudomonas sphaeroides lipid A
24. Human granulocytes express a 55 kDa lipopolysaccharide binding protein on the cell surface that is identical to the bactericidal/permeability-increasing protein
25. Identification of Re lipopolysaccharide-binding protein on murine erythrocyte membrane
26. Detection of lipopolysaccharide binding proteins on membranes of mufine lymphocyte and macrophage-like cell lines
27. An amino-terminal fragment of human lipopolysaccharide-binding protein retains lipid A binding but not CD14-stimulatory activity
28. A region of human CD14 required for lipopolysaccharide-binding
29. Identification of lipopolysaccharide binding protein with specificity for an inner core region (kDaO) determinant
30. Detection of lipopolysaccharide (LPS)-binding membrane proteins by immuno-coprecipitation with LPS and anti-LPS antibodies
31. Cell bound albumin is the 70 kDa peptidoglycan-, lipopolysaccharide, and lipoteichoic acid-binding protein on lymphocytes and macrophages
32. Identification of the 80-kDa LPS-binding protein (LMP-80): As decay-accelerating factor (DAF, CD55)
33. Identification and characterisation of lipopolysaccharide binding proteins on human peripheral blood cell populations
34. Biosynthetic radiolabelling of bacterial lipopolysaccharide to high specific activity
35. Endotoxaemia: An early predictor of septicaemia in febrile patients