Pentanoic acid, a novel protein synthesis stimulant for Chinese Hamster Ovary (CHO) cells

Journal of Bioscience and Bioengineering

Volumn 91, Issue 1, 2001, Pages 71-75

  Liu, Chi Hsien ^a   Chu, I Ming ^a   Hwang, Shiaw Min ^b  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^b FOOD INDUSTRY RESEARCH AND DEVELOPMENT INSTITUTE   (Taiwan)

Author keywords

Apoptosis; Butyrate; CHO cells; Pentanoic acid; Protein synthesis stimulant

Indexed keywords

BUTYRIC ACID; CARBOXYLIC ACID; HYBRID PROTEIN; VALERIC ACID;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL GROWTH; CHO CELL; CONTROLLED STUDY; GROWTH INHIBITION; NONHUMAN; PROTEIN SYNTHESIS;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS;

EID: 0035110023     PISSN: 13891723     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1389-1723(01)80114-6     Document Type: Article

References (15)

1. Expression of recombinant plasmids in the mammalian cells is enhanced by sodium butyrate
2. Butyrate stimulates tissue-type plasminogen-activator synthesis in cultured human endothelial cells
3. Production of analytical quantities of recombinant proteins in Chinese hamster ovary cells using sodium butyrate to elevate gene expression
4. Induction of recombinant gamma-glutamyl transferase by sodium butyrate in transfected V79 and CHO
5. Role of environmental conditions on the expression levels, glycoform pattern and levels sialytransferase for hFSH produced by recombinant CHO cells
6. Na-butyrate increases the production of alfa2,6-sialylation of recombinant interferon-gamma expressed by alfa2,6-sialyltransferase engineered CHO cells
7. A serum-free medium for hybridoma cell culture
8. Stimulation of monoclonal antibody production of hybridoma cells by butyrate: Evaluation of a feeding strategy and characterization of cell behavior
9. Substantial overproduction of antibodies by applying osmotic pressure and sodium butyrate
10. Cell-cycle-dependent protein accumulation by producer and nonproducer murine hydridoma cell lines: A population analysis
11. Foreign gene expression (beta-galactosidase) during the cell cycle phases in recombinant CHO cells
12. One way analysis of variance
13. An increase in histone acetylation and IL-2 antagonizing the immunoinhibitory effect are necessary for augmentation by butyrate of in vitro anti-TNP antibody production
14. Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors
15. Apoptosis in batch cultures of Chinese hamster ovary cells