Long-term dehydroepiandrosterone and 16α-fluoro-5-androsten-17-one administration enhances DNA synthesis and induces expression of c-fos and c-Ha-ras in a selected population of preneoplastic lesions in liver of diethylnitrosamine-initiated rats

Carcinogenesis

Volumn 22, Issue 2, 2001, Pages 301-308

  Simile, M M ^a   De Miglio, M R ^a   Calvisi, D ^a   Muroni, M R ^a   Frau, M ^a   Asara, G ^a   Daino, L ^a   Deiana, L ^a   Pascale, R M ^a   Feo, F ^a  

^a Dipartimento di Scienze Biomediche   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DIETHYLNITROSAMINE; DNA; DRUG ANALOG; FLUASTERONE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUTATHIONE TRANSFERASE; N (2 FLUORENYL)ACETAMIDE; PRASTERONE; PROTEIN C FOS; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INHIBITION; CARCINOGENESIS; CELL GROWTH; CELL SUBPOPULATION; CELL TRANSFORMATION; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; GENE OVEREXPRESSION; GENOTOXICITY; LABELING INDEX; LIVER CELL CARCINOMA; LIVER INJURY; MALE; NONHUMAN; ONCOGENE C FOS; ONCOGENE C H RAS; PARANEOPLASTIC SYNDROME; PARTIAL HEPATECTOMY; PLACENTA; POPULATION; PRIORITY JOURNAL; PROTEIN DIET; RAT;

ANIMALS; CARCINOMA, HEPATOCELLULAR; DEHYDROEPIANDROSTERONE; DIET; DIETHYLNITROSAMINE; DNA; DNA REPLICATION; DRUG RESISTANCE; GLUCOSEPHOSPHATE DEHYDROGENASE; GLUTATHIONE TRANSFERASE; HEPATOCYTES; IMMUNOENZYME TECHNIQUES; LIVER NEOPLASMS, EXPERIMENTAL; PROTO-ONCOGENE PROTEINS C-FOS; PROTO-ONCOGENE PROTEINS P21(RAS); RATS; RATS, INBRED F344;

EID: 0035109421     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/22.2.301     Document Type: Article

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