Effect of nuclear factor κB inhibition on tumor cell sensitivity to natural killer-mediated cytolytic function

European Journal of Immunology

Volumn 31, Issue 2, 2001, Pages 433-439

  Mami Chouaib, Fathia ^a   Ameyar, Maya ^a   Dorothée, Guillaume ^a   Bentires Alj, Mohamed ^b   Dziembowska, Magdalena ^c   Delhalle, Silvie ^b   Gay, Françoise ^a   Stancou, Rodica ^a   Bours, Vincent ^b   Chouaib, Salem ^a  

^a INSTITUT GUSTAVE ROUSSY   (France)

^b UNIVERSITY OF LIÈGE   (Belgium)

^c NENCKI INSTITUTE OF EXPERIMENTAL BIOLOGY   (Poland)

Author keywords

Cytotoxicity; Human NK cell; NF B

Indexed keywords

CD48 ANTIGEN; COMPLEMENTARY DNA; CYTOTOXIC AGENT; DNA; EGTAZIC ACID; FAS ANTIBODY; FAS ANTIGEN; FAS LIGAND; GRANZYME A; GRANZYME B; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; LYMPHOCYTE ANTIGEN RECEPTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MONOCLONAL ANTIBODY; OKT 3; OKT 4; PERFORIN; PROTEIN INHIBITOR; RECOMBINANT TUMOR NECROSIS FACTOR; RNA; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR DELTA CHAIN; T LYMPHOCYTE RECEPTOR GAMMA CHAIN; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNINDEXED DRUG;

ARTICLE; BINDING AFFINITY; CELL ACTIVITY; CELL CLONE; CELL CULTURE; CELL ISOLATION; CELL STIMULATION; CONTROL SYSTEM; CONTROLLED STUDY; CYTOLYSIS; DRUG SENSITIVITY; ELECTROPHORETIC MOBILITY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; MAJOR HISTOCOMPATIBILITY COMPLEX; MOLECULAR BIOLOGY; NATURAL KILLER CELL MEDIATED CYTOTOXICITY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DNA BINDING; PROTEIN EXPRESSION; T LYMPHOCYTE; TARGET CELL; TUMOR CELL;

CYTOTOXICITY, IMMUNOLOGIC; DNA-BINDING PROTEINS; HUMANS; I-KAPPA B PROTEINS; KILLER CELLS, NATURAL; NF-KAPPA B; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0035108282     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200102)31:2<433::AID-IMMU433>3.0.CO;2-T     Document Type: Article

References (21)

1. The NF-kappe B and I kappa B proteins: New discoveries and insights
2. Rel/NF-kappa B and I kappa B factors in oncogenesis
3. Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: A mechanism for NF-kappa B activation
4. An essential role for NF-kappaB in preventing TNF-alpha-induced cell death
5. TNF- and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-kappaB
6. Embryonic lethality and liver degeneration in mice lacking the ReIA component of NF-kappa B
7. Inhibition of nuclear factor kappaB activation attenuates apoptosis resistance in lymphoid cells
8. Control of inducible chemoresistance: Enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-κB
9. Lymphocyte-mediated cytotoxicity: Two pathways and multiple effector molecule
10. Caspase dependence of target cell damage induced by cytotoxic lymphocytes
11. CD48 may serve as an accessory molecule for the activation of a subset of human gamma/delta T cells
12. Human NK cells constitutively express membrane TNF-α (mTNFα) and present mTNFα-dependent cytotoxic activity
13. N- and C-terminal sequences control degradation of MAD3/I kappa B alpha in response to inducers of NF-kappa B activity
14. Demonstration by class I gene transfer that reduced susceptibility of human cells to natural killer cell-mediated lysis is inversely correlated with HLA class I antigen expression
15. P58 molecules as putative receptors for major histocompatibility complex (MHC) class I molecules in human natural killer (NK) cells. Anti-p58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones different specificities
16. Retinoic acid induction of major histocompatibility complex class I genes in NTera-2 embryonal carcinoma cells involves induction of NF-kappa B (p50-p65) and retinoic acid receptor beta-retinoid X receptor beta heterodimers
17. Stable inhibition of nuclear factor kappaB in cancer cells does not increase sensitivity to cytotoxic drugs
18. Molecular mechanism of constitutive NF-kappaB/Rel activation in Hodgkin/Reed-Sternberg cells
19. Nuclear factor - KappaB-dependent regulation of p53 gene expression induced by daunomycin genotoxic drug
20. IkappaB alpha overexpression in human breast carcinoma MCF7 cells inhibits nuclear factor-kappaB activation but not tumor necrosis factor- alpha-induced apoptosis
21. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei