Optimization of binding electrostatics: Charge complementarity in the barnase-barstar protein complex

Protein Science

Volumn 10, Issue 2, 2001, Pages 362-377

  Lee, Lee Peng ^a   Tidor, Bruce ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Binding affinity; Electrostatic optimization; Molecular recognition; Protein electrostatics

Indexed keywords

BARNASE; BARNASE BARSTAR PROTEIN COMPLEX; BARSTAR; UNCLASSIFIED DRUG;

ALGORITHM; AQUEOUS SOLUTION; ARTICLE; COMPLEX FORMATION; ELECTRICITY; ENERGY TRANSFER; GEOMETRY; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN STABILITY; SOLVATION;

ALGORITHMS; BACTERIAL PROTEINS; ENZYME INHIBITORS; HYDROGEN BONDING; HYDROGEN-ION CONCENTRATION; KINETICS; MODELS, MOLECULAR; MODELS, STATISTICAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RIBONUCLEASES; TEMPERATURE; THERMODYNAMICS; WATER;

EID: 0035107570     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.40001     Document Type: Article

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