Electrostatic interactions in hirudin-thrombin binding

Biophysical Chemistry

Volumn 61, Issue 1, 1996, Pages 37-49

  Sharp, Kim A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Binding; Electrostatics; Finite Difference; Hirudin; Poisson Boltzmann; Thrombin

Indexed keywords

ANTICOAGULANT AGENT; HIRUDIN; THROMBIN;

ARTICLE; CALCULATION; CHEMICAL STRUCTURE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DRUG BINDING; IONIC STRENGTH; PRIORITY JOURNAL;

EID: 0030606788     PISSN: 03014622     EISSN: None     Source Type: Journal    
DOI: 10.1016/0301-4622(96)00021-X     Document Type: Article

References (34)

1. [1] D. Bagdy, E. Barabas, L. Graf, T.E. Petersen and S. Magnusson, Methods Enzymol., 45 (1976) 669-678.
2. [2] S.R. Stone, A. Betz, M.A. Parry, M.P. Jackman and J. Hofsteenge, Adv. Exp. Med. Biol., 340 (1993) 35-49.
3. [3] S.R. Stone and J. Hofsteenge, Biochemistry, 25 (1986) 4622-4628.
4. [4] P.J. Braun, S. Dennis, J. Hofsteenge and S.R. Stone, Biochemistry, 27 (1988) 6517-6522.
5. [5] S. Stone, S. Dennis and J. Hofsteenge, Biochemistry, 28 (1989) 6857-6863.
6. [6] T.J. Rydel, A. Tulinsky, W. Bode and R. Huber, J. Mol. Biol., 221 (1991) 583.
7. [7] J.Y. Chang, FEBS Lett., 164 (1983) 307-313.
8. [8] E. Di Cera, E. Guinto, A. Vindigni, Q. Dang, Y. Ayala, M. Wuyi and A. Tulinsky, J. Biol. Chem., 270 (1995) 22089-22092.
9. [9] Y. Ayala and E. Di Cera, J. Mol. Biol., 235 (1994) 733-746.
10. [10] A. Karshikov, W. Bode, A. Tulinsky and S. Stone, Protein Sci., 1 (1992) 727-735.
11. [11] V. Misra, J. Hecht, K. Sharp, R. Friedman and B. Honig, J. Mol. Biol., 238 (1994) 264-280.
12. [12] V. Misra, K. Sharp, R. Friedman and B. Honig, J. Mol. Biol., 238 (1994) 245-263.
13. [13] M.K. Gilson and B. Honig, Proteins, 4 (1988) 7-18
14. [14] M. Zacharias, B. Luty, M. Davis and J. McCammon, Biophys. J., 63 (1992) 1280-1285.
15. [15] V. Misra and B. Honig, Proc. Natl. Acad. Sci. USA, 92 (1995) 4691-4695.
16. [16] J. Shen and J. Wendoloski, Protein Sci., 4 (1995) 373-381.
17. [17] M. Fushiki, B. Svensson, B. Jonsson and C.E. Woodward, Biopolymers, 31 (1991) 1149-1158.
18. [18] J.B. Matthew and F.R. Gurd, Methods Enzymol., 130 (1986) 413-453.
19. [19] K. Sharp and B. Honig, Ann. Rev. Biophys. Biophys. Chem., 19 (1990) 301-332.
20. [20] D. Sitkoff, K. Sharp and B. Honig, J. Phys. Chem., 98 (1994) 1978-1988.
21. [21] F. Bernstein, T. Koetzle, G. Williams, E. Meyer, M. Brice, J. Rodgers, O. Kennard, T. Shimanouchi and M. Tasumi, J. Mol. Biol., 112 (1977) 535-542.
22. [22] D.J. Barlow and J.M. Thornton, J. Mol. Biol., 168 (1983) 867-885.
23. [23] M. Gilson, K.A. Sharp and B. Honig, J. Comput. Chem., 9 (1988) 327-335.
24. [24] A. Nicholls, K.A. Sharp and H. Honig, Proteins, 11 (1991) 281-296.
25. [25] M. Holst and F. Saied, J. Comput. Chem., 14 (1993) 105-113.
26. [26] K.A. Sharp, R. Friedman, V. Misra, J. Hecht and B. Honig, Biopolymers, 36 (1995) 245-262.
27. [27] A. Yang, M. Gunner, R. Sampogna, K. Sharp and B. Honig, Proteins - Struct. Funct. Genet., 15 (1993) 252-265.
28. [28] A. Horovitz and A.R. Fersht, J. Mol. Biol., 224 (1992) 733-40.
29. [29] K. Langsetmo, J.A. Fuchs, C. Woodward and K.A. Sharp, Biochemistry, 30 (1991) 7609-7614.
30. [30] D. Bashford, D. Case, C. Dalvit, L. Tennant and P. Wright, Biochemistry, 32 (1993) 8045-8056.
31. [31] M. Gilson, Proteins - Struct. Funct. Genet., 15 (1993) 266-282.
32. [32] Z.S. Hendsch and B. Tidor, Protein Sci., 3 (1994) 211-226.
33. [33] J. Madura and M. Gilson, Biophys. J., 64 (1993) A 220.
34. [34] A. Yang and B. Honig, J. Molec. Biol., 231 (1993) 459-474.