3-Hydroxy-3-methylglutaryl coenzyme A synthase-1 of Blattella germanica has structural and functional features of an active retrogene

Insect Biochemistry and Molecular Biology

Volumn 31, Issue 4-5, 2001, Pages 425-433

  Casals, Núria ^a,c   Buesa, Carlos ^a   Marrero, Pedro F ^a   Belles, Xavier ^b   Hegardt, Fausto G ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b INSTITUT DE BIOLOGIA MOLECULAR DE BARCELONA   (Spain)

^c UNIVERSITAT INTERNACIONAL DE CATALUNYA   (Spain)

Author keywords

Blatella germanica; Compactin; HMG CoA reductase; HMG CoA synthase; Intron less gene; Mevalonate; Retrogene

Indexed keywords

COMPACTIN; GENE PRODUCT; HYDROXYMETHYLGLUTARYL COA REDUCTASE INHIBITORS; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; HYDROXYMETHYLGLUTARYL COENZYME A SYNTHASE; HYDROXYMETHYLGLUTARYL COENZYME A SYNTHASE 1; HYDROXYMETHYLGLUTARYL COENZYME A SYNTHASE 2; INSECT PROTEIN; MEVALONIC ACID; MEVINOLIN; UNCLASSIFIED DRUG;

ANIMAL; ARTICLE; BLATTELLIDAE; CELL CULTURE; CELL LINE; COCKROACH; COMPARATIVE STUDY; CONTROLLED STUDY; DNA FLANKING REGION; ENZYME ACTIVITY; ENZYME STRUCTURE; GENE; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE SEQUENCE; GENE STRUCTURE; GENETIC TRANSCRIPTION; INTRON; MOLECULAR GENETICS; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; RETROPOSON; SEQUENCE ANALYSIS; SPECIES DIFFERENCE;

ANIMALS; BASE SEQUENCE; COCKROACHES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENES, INSECT; HYDROXYMETHYLGLUTARYL COA REDUCTASES; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; INSECT PROTEINS; INTRONS; LOVASTATIN; MEVALONIC ACID; MOLECULAR SEQUENCE DATA; RETROELEMENTS; SPECIES SPECIFICITY;

BLATTELLA GERMANICA; INSECTA; MINK ENTERITIS VIRUS;

EID: 0035106273     PISSN: 09651748     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0965-1748(00)00137-5     Document Type: Article

References (40)

1. Insect lipids and lipoproteins, and their role in physiological processes
2. Transcription factors and the control of Drosophila development
3. Isoprene synthesis in isolated embryonic Drosophila cells. II. Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity
4. Multivalent feedback regulation of HMG-CoA reductase, a control mechanism coordinating isoprenoid synthesis and cell growth
5. Blattella germanica has two HMG-CoA synthase genes
6. Catalytic properties of recombinant 3-hydroxy-3-methylglutaryl coenzyme A synthase-1 from Blattella germanica
7. An RNA polymerase II transcription factor binds to an upstream element in the adenovirus major late promoter
8. Coordinated expression and activity of 3-hydroxy-3-methylglutaryl coenzyme A synthase and reductase in the fat body of Blatella germanica during vitellogenesis
9. Molecular cloning and tissue expression of an insect farnesyl diphosphate synthase
10. Cytosolic 3-hydroxy-3-methylglutaryl coenzyme A synthase from chicken liver
11. Assay of HMG-CoA synthase in Diploptera punctata corpora allata
12. A comprehensive set of sequences analysis programs for the VAX
13. Feedback regulation of 3-hydroxy-methylglutaryl coenzyme A reductase in Saccharomyces cerevisiae
14. Determining divergence times of the major kingdoms of living organisms with a protein clock
15. Molecular cloning and structural analysis of 3-hydroxy-3-methylglutaryl coenzyme A reductase of the moth Agrotis ipsilon
16. Characterization and regulation of HMG-CoA reductase during a cycle of juvenile hormone synthesis
17. Developmental and metabolic regulation of the Drosophila melanogaster 3-hydroxy-3-methylglutaryl coenzyme A reductase
18. Cytoplasmic 3-hydroxy-3-methylglutaryl coenzyme A synthase from the hamster
19. Cytoplasmic 3-hydroxy-3-methylglutaryl coenzyme A synthase from the hamster. II. Isolation of the gene and characterization of the 5′ flanking region
20. Receptor mediated endocytosis of low-density lipoprotein in cultured cells
21. Regulation of the mevalonate pathway
22. Isolation of a cDNA encoding the adenovirus E1A enhancer binding protein: A new human member of the ets oncogene family
23. Translational and transcriptional control elements in the untranslated leader of the heat-shock gene hsp22
24. Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements
25. The viruses in all of us: Characteristics and biological significance of human endogenous retro-virus sequences
26. Molecular cloning, developmental pattern and tissue expression of 3-hydroxy-3-methylglutaryl coenzyme A reductase of the cockroach Blattella germanica
27. 3-Hydroxy-3-methylglutaryl-CoA synthase from Blattella germanica
28. Rapid amplification of genomic DNA ends
29. Formulation of medium for tick cell culture
30. Inhibition of squalene synthase but not squalene cyclase prevents mevalonate-mediated suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase synthesis at a post-transcriptional level
31. HMG-CoA reductase regulation: Use of structurally diverse first half-reaction squalene synthetase inhibitors to characterize the site of mevalonate-derived nonsterol regulator production in cultured IM-9 cells
32. HMG CoA reductase: A negatively regulated gene with unusual promoter and 5′ untranslated regions
33. Isolation and characterization of a mammalian cell mutant defective in 3-hydroxy-3-methylglutaryl coenzyme A synthase
34. Isoprene synthesis in isolated embryonic Drosophila cells. I. Sterol-deficient eukaryotic cells
35. Post-transcriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by mevalonate
36. Phylogeny reconstruction
37. SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis
38. Nonviral retroposons: Genes, pseudogenes, and transposable elements generated by the reverse flow of genetic information
39. Analysis of the DNA-binding and activation properties of the human transcription factor AP-2