Stabilizing interactions in the dimer interface of α-subunit in Escherichia coli RNA polymerase: A graph spectral and point mutation study

Protein Science

Volumn 10, Issue 1, 2001, Pages 46-54

  Kannan, N ^a   Chander, P ^a   Ghosh, P ^a   Vishveshwara, S ^a   Chatterji, D ^a  

^a INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

Assembly; Graph spectral algorithm; N terminal domain; Point mutation; RNA polymerase; subunit

Indexed keywords

DIMER; RNA POLYMERASE;

ALGORITHM; ALPHA CHAIN; AMINO TERMINAL SEQUENCE; ARTICLE; CRYSTAL STRUCTURE; DIMERIZATION; ESCHERICHIA COLI; POINT MUTATION; PRIORITY JOURNAL; THERMUS AQUATICUS;

ALGORITHMS; AMINO ACID SEQUENCE; CONSERVED SEQUENCE; DIMERIZATION; DNA-DIRECTED RNA POLYMERASES; ESCHERICHIA COLI; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; POINT MUTATION; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; SPECTRUM ANALYSIS; TEMPERATURE;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; THERMUS AQUATICUS;

EID: 0035104601     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.26201     Document Type: Article

References (21)

1. Anatomy of hot spots in protein interfaces
2. Principles of protein-protein recognition
3. The molecular surface package
4. The E. coli RNA polymerase α subunit: Structure and function
5. Side chain clusters in protein structures and their role in protein folding
6. VMD-Visual molecular dynamics
7. Bipartite functional map of the E. coli RNA polymerase α subunit: Involvement of the C-terminal region in transcription activation by cAMP-CRP
8. Subunit assembly of Escherichia coli RNA polymerase
9. Analysis of protein-protein interaction sites using surface patches
10. Identification of side-chain clusters in protein structures by a graph spectral method
11. Functional map of the α subunit of E. coli RNA polymerase: Amino acid substitution within the amino terminal assembly domain
12. Subunit assembly in vivo of E. coli RNA polymerase: Role of the amino terminal domain assembly domain of α subunit
13. Functional map of the α subunit of E. coli RNA polymerase
14. Morphology of protein-protein interfaces
15. Experimental evolution of a dense cluster of residues in tyrosyl-tRNA synthetase: Quantitative effects on activity, stability and dimerisation
16. Classification of polymer structures by graph theory
17. 65Zn blotting
18. Functional complementation between mutations at two distant positions in E. coli RNA polymerase as revealed by second-site suppression
19. Structure of the E. coli RNA polymerase α subunit amino-terminal domain
20. Crystal structure of Thermus aquaticus core RNA polymerase at 3.3Å resolution