Drosophila telomeric transgenes provide insights on mechanisms of gene silencing

Genetica

Volumn 109, Issue 1-2, 2000, Pages 25-33

  Wallrath, Lori L ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

Chromatin; Drosophila; Heterochromatin; Position effect variegation; Telomeres

Indexed keywords

ANIMALIA; DROSOPHILA; EUKARYOTA;

EID: 0035102955     PISSN: 00166707     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1026556705137     Document Type: Review

References (59)

1. Mutations derepressing silent centromeric domains in fission yeast disrupt chromosome segregation
2. Modifiers of position effect are shared between telomeric and silent mating-type loci in S. cerevisiae
3. In vivo chromatin accessibility correlates with gene silencing in Drosophila
4. Dynamic repositioning of genes in the nucleus of lymphocytes preparing for cell division
5. Nucleosomal instability and induction of new upstream protein-DNA associations accompany activation of four small heat shock protein genes in Drosophila melanogaster
6. Cleavage of chromatin with methidiumpropyl-EDTA iron(II)
7. Nuclear compartments and gene regulation
8. Characterization of sequences associated with position effect variegation at pericentric sites in Drosophila heterochromatin
9. Silencing at Drosophila telomeres: Nuclear organization and chromatin structure play critical roles
10. Heterochromatic silencing of Drosophila heat shock genes acts at the level of promoter potentiation
11. Genetic modification of heterochromatic association and nuclear organization in Drosophila
12. Perturbation of nuclear architecture by long-distance chromosome interactions
13. Variegated gene expression in mice
14. Fission yeast mutants that alleviate transcriptional silencing in centromeric flanking repeats and disrupt chromosome segregation
15. The heterochromatin protein 1 (HP1) prevents telomere fusions in Drosophila melanogaster
16. The Trithorax-like gene encodes the Drosophila GAGA factor
17. A functional enhancer suppresses silencing of a transgene and prevents its localization close to centrometric heterochromatin
18. Position effect at S. cerevisiae telomeres: Reversible repression of Pol II transcription
19. Chromatin. Ga-ga over GAGA factor
20. ATP-dependent histone octamer sliding mediated by the chromatin remodeling complex NURF
21. Spatial organization of chromosomes in the salivary gland nuclei of Drosophila melanogaster
22. Distribution patterns of HP1, a heterochromatin-associated nonhistone chromosomal protein of Drosophila
23. Analysis of subtelomeric heterochromatin in the Drosophila minichromosome Dp1187 by single P element insertional mutagenesis
24. Position effect in human genetic disease
25. The chromo superfamily: New members, duplication of the chromo domain and possible role in delivering transcription regulators to chromatin
26. Hoppel-family of mobile elements of Drosophila melanogaster, flanked by short inverted repeats and having preferential localization in the heterochromatin regions of the genome
27. Transposons in place of telomeric repeats at a Drosophila telomere
28. The characterization of DINE-1, a short, interspersed repetitive element present on chromosome and in the centric heterochromatin of Drosophila melanogaster
29. Analysis of Drosophila chromosome 4 using pulsed field gel electrophoresis
30. The role of a positioned nucleosome at the Drosophila melanogaster hsp26 promoter
31. n repeats and heat shock elements have distinct roles in chromatin structure and transcriptional activation of the Drosophila hsp26 gene
32. Microcloning reveals a high frequency of repetitive sequences characteristic of chromosome 4 and the beta-heterochromatin of Drosophila melanogaster
33. Histone acetylation facilitates RNA polymerase II transcription of the Drosophila hsp26 gene in chromatin
34. Telomeres and telomerase: More than the end of the line
35. Transposable elements are stable structural components of Drosophila melanogaster heterochromatin
36. Polycombing the genome: PcG, trxG, and chromatin silencing
37. Changes in chromosomal localization of heterochromatin-binding proteins during the cell cycle in Drosophila
38. TFIID sequence recognition of the initiator and sequences farther downstream in Drosophila class II genes
39. Related chromosome binding sites for zeste, suppressors of zeste and Polycomb group proteins in Drosophila and their dependence on enhancer of zeste function
40. High-resolution structural analysis of chromatin at specific loci: Saccharomyces cerevisiae silent mating-type locus HMRα
41. A stable genomic source of P element transposase in Drosophila melanogaster
42. Postinitiation transcriptional control in Drosophila melanogaster
43. Genetic transformation of Drosophila with transposable element vectors
44. Transposition of the LINE-like retrotransposon TART to Drosophila chromosome termini
45. Enhancer of Polycomb is a suppressor of position-effect variegation in Drosophila melanogaster
46. A sequence motif found in a Drosophila heterochromatin protein is conserved in animals and plants
47. Protein/DNA architecture of the DNase I hypersensitive region of the Drosophila hsp26 promoter
48. Chromatin remodeling and transcription
49. Histone H4 isoforms acetylated at specific lysine residues define individual chromosomes and chromatin domains in Drosophila polytene nuclei
50. Unfolding the mysteries of heterochromatin
51. Position effect variegation in Drosophila is associated with an altered chromatin structure
52. DNA representation of variegating heterochromatic P-element inserts in diploid and polytene tissues of Drosophila melanogaster
53. DNA organization and polymorphism of a wild-type Drosophila telomere region
54. Heterochromatin and gene expression in Drosophila
55. High-resolution structural analysis of chromatin at specific loci: Saccharomyces cerevisiae silent mating type locus HMLα
56. Dynamics of potentiation and activation: GAGA factor and its role in heat shock gene regulation
57. A genetic analysis of the Suppressor 2 of zeste complex of Drosophila melanogaster
58. The Drosophila salivary gland chromocenter contains highly polytenized subdomains of mitotic heterochromatin