The role of tissue microdissection in cancer research

Cancer Journal

Volumn 7, Issue 1, 2001, Pages 32-39

  Gillespie, J W ^a   Ahram, M ^a   Best, C J M ^a   Swalwell, J I ^a   Krizman, D B ^a   Petricoin, E F ^a   Liotta, L A ^a   Emmert Buck, M R ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Gene expression; Molecular pathology; Proteomics; Tissue microdissection

Indexed keywords

DNA; MESSENGER RNA;

CANCER RESEARCH; CELL POPULATION; CHROMOSOME MICRODISSECTION; EVOLUTION; GENE EXPRESSION; LABORATORY DIAGNOSIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; REVIEW; TISSUE SECTION;

DNA, NEOPLASM; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; GENE LIBRARY; GENES, TUMOR SUPPRESSOR; HUMANS; LASER SURGERY; MALE; MONITORING, INTRAOPERATIVE; MULTIPLE ENDOCRINE NEOPLASIA TYPE 1; NEOPLASMS; PROSTATIC NEOPLASMS; RNA, MESSENGER; RNA, NEOPLASM; SEQUENCE ANALYSIS, DNA; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0035098020     PISSN: 15289117     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (46)

1. Clonal analysis of human colorectal tumors
2. Allelic loss on a chromosome 17 in ductal carcinoma in situ of the breast
3. Increased gelatinase A (MMP-2) and cathepsin B activity in invasive tumor regions of human colon cancer samples
4. Practical histological microdissection for PCR analysis
5. Microdissection and polymerase chain reaction amplification of genomic DNA from histological tissue sections
6. Specific genetic analysis of microscopic tissue after selective ultraviolet radiation fractionation and polymerase chain reaction
7. Non-contact laser microdissection of membrane-mounted native tissue
8. Identification of expressed genes by laser-mediated manipulation of single cells
9. Laser capture microdissection
10. Laser capture microdissection molecular analysis of tissue
11. Immuno-LCM: Laser capture microdissection of immunostained frozen sections for mRNA analysis
12. Purification of DNA from formaldehyde fixed and paraffin embedded human tissue
13. Effects of ethanol and paraformaldehyde on RNA yield and quality
14. Molecular biological analysis of paraffin-embedded tissues
15. Evolution of genetic abnormalities in hepatocellular carcinomas demonstrated by DNA fingerprinting
16. Composite low-grade B-cell lymphomas with two immunophenotypically distinct cell populations are true biclonal lymphomas: A molecular analysis using laser capture microdissection
17. High frequency and heterogeneous distribution of p53 mutations in aflatoxin B1-induced mouse lung tumors
18. Direct visualization of the clonal progression of primary cutaneous melanoma: Application of tissue microdissection and comparative genomic hybridization
19. Positional cloning of the gene for multiple endocrine neoplasia type 1
20. Localization of the multiple endocrine neoplasia type 1 (MEN 1) gene based on tumor loss of heterozygosity analysis
21. 11q13 allelo-type analysis in 27 Northern American MEN1 kindreds identifies two distinct founder chromosomes
22. Haplotype analysis defines a minimal interval for the multiple endocrine neoplasia type 1 (MEN1) gene
23. Identification of MEN1 gene mutations in sporadic carcinoid tumors of the lung
24. Analysis of 99 microdissected prostate carcinomas reveals high frequency of allelic loss on chromosome 8p12-21
25. Allelic loss on chromosome 8p12-21 in microdissected prostatic intraepithelial neoplasia (PIN)
26. Gene expression profiles of laser-captured adjacent neuronal subtypes
27. Quantitative monitoring of gene expression patterns with a complementary DNA microarray
28. Use of a cDNA microarray to analyse gene expression patterns in human cancer
29. Expression monitoring by hybridization to high-density oligonucleotide arrays
30. Light-directed synthesis of high-density oligonucleotide arrays using semiconductor photoresists
31. PB39: Identification of a novel gene up-regulated in clinically aggressive human prostate cancer
32. cDNA sequencing and analysis of PB39: A novel gene up-regulated in prostate cancer
33. Molecular profiling of clinical tissue specimens: Feasibility and applications
34. Serial analysis of gene expression
35. Gene expression profiles in normal and cancer cells
36. MicroSAGE: A modified procedure for serial analysis of gene expression in limited amounts of tissue
37. A strategic approach for proteomic analysis of human tumors
38. Tissue proteomics at the microscale: A novel approach to the study of disease progression
39. Sensitive immunoassay of tissue cell proteins procured by laser capture microdissection
40. Proteome and proteomics new technologies, new concepts, and new words
41. Proteomics translating genomics into products?
42. The potential use of laser capture microdissection to selectively obtain distinct populations of cells for proteomic analysis, preliminary findings
43. Proteomic analysis of laser capture microdissected human prostate cancer and in vitro prostate cell lines
44. Bactericidal domain of lactoferrin: Detection, quantitation, and characterization of lactoferricin in serum by SELDI affinity mass spectrometry
45. Layered expression scanning: Rapid molecular profiling of tumor samples
46. The genetics of cancer: A 3D model