Excess growth and apoptosis is hypertension a case of accelerated aging of cardiovascular cells?

Hypertension

Volumn 37, Issue 2 II, 2001, Pages 760-766

  Hamet, Pavel ^a   Thorin Trescases, Nathalie ^a   Moreau, Pierre ^a   Dumas, Pierre ^a   Tea, Ben Sung ^a   DeBlois, Denis ^a   Kren, Vladimir ^c   Pravenec, Michal ^b,c   Kunes, Jaroslav ^c   Sun, Yulin ^a   Tremblay, Johanne ^a  

^a CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^b CHARLES UNIVERSITY   (Czech Republic)

^c INSTITUTE OF PHYSIOLOGY   (Czech Republic)

Author keywords

Aging; Apoptosis; Genetics; Growth; Hypertension; Telomeres

Indexed keywords

GENE PRODUCT; PROTEIN MLH1; UNCLASSIFIED DRUG; DNA; DNA FRAGMENT; THYMIDINE; TRITIUM;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; CELL AGING; CELL GROWTH; CHROMOSOME 1; CONFERENCE PAPER; CONTROLLED STUDY; FEMALE; GENE LOCUS; GENE MAPPING; GROWTH REGULATION; HEART VENTRICLE HYPERTROPHY; HYPERTENSION; MALE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; RENOVASCULAR HYPERTENSION; SPONTANEOUSLY HYPERTENSIVE RAT; ANIMAL; ARTICLE; BODY WEIGHT; BROWN NORWAY RAT; CROSS BREEDING; GENETICS; GROWTH, DEVELOPMENT AND AGING; HEART; HEART MUSCLE; ISOLATION AND PURIFICATION; KIDNEY; METABOLISM; ORGAN SIZE; PATHOLOGY; PRENATAL DEVELOPMENT; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; TELOMERE; WISTAR KYOTO RAT;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; BODY WEIGHT; CELL AGING; CROSSES, GENETIC; DNA; DNA FRAGMENTATION; FEMALE; HEART; HYPERTENSION; KIDNEY; MALE; MYOCARDIUM; ORGAN SIZE; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RATS; RATS, INBRED BN; RATS, INBRED SHR; RATS, INBRED WKY; TELOMERE; THYMIDINE; TRITIUM;

EID: 0035097473     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.hyp.37.2.760     Document Type: Conference Paper

References (54)

1. Physiological aspects of primary hypertension
2. Hypertension as a cardiovascular proliferative disorder
3. A new approach to the prevention of hypertensive cardiovascular diseases by controlling the proliferation of vascular smooth muscle cells
4. Primary versus secondary events in hypertension
5. Abnormalities in growth characteristics of aortic smooth muscle cells in spontaneously hypertensive rats
6. Epidermal growth factor responsiveness in smooth muscle cells from hypertensive and normotensive rats
7. Differential regulation by transforming growth factor-beta 1 of platelet-derived growth factor-stimulated proliferation of vascular smooth muscle cells from SHR and WKY rats
8. Enhanced proliferating activity of cultured smooth muscle cells from SHR
9. Apoptosis in target organs of hypertension
10. Proliferation and apoptosis in hypertension
11. The time window of apoptosis: A new component in the therapeutic strategy for cardiovascular remodeling
12. Smooth muscle apoptosis during vascular regression in spontaneously hypertensive rats
13. Apoptosis during regression of cardiac hypertrophy in spontaneously hypertensive rats: Temporal regulation and spatial heterogeneity
14. Structure and mechanical properties of resistance arteries in hypertension: Role of adhesion molecules and extracellular matrix determinants
15. Altered balance between cell replication and apoptosis in hearts and kidneys of newborn SHR
16. Cardiac and renal hyperplasia in newborn genetically hypertensive rats
17. An analysis of spontaneous hypertension in spontaneously hypertensive rats by means of new recombinant inbred strains
18. Developmentally timed expression of an embryonic growth phenotype in vascular smooth muscle cells
19. Telomere length, telomerase activity and telomerase RNA expression in human esophageal cancer cells: Correlation with cell proliferation, differentiation and chemosensitivity to anticancer drugs
20. Telomerase activity in gastric cancer
21. Telomere length in human white blood cells remains constant with age and is shorter in breast cancer patients
22. Conserved nucleoprotein structure at the ends of vertebrate and invertebrate chromosomes
23. Cardiac and renal hyperplasia in newborn spontaneously hypertensive rats
24. Myocardial hypertrophy and ventricular performance in the absence of hypertension in spontaneously hypertensive rats
25. Pressure profiles in neonatal spontaneously hypertensive rats
26. Enhanced DNA synthesis in heart and kidney of newborn spontaneously hypertensive rats
27. Heart size in inbred strains of rats, II: Genetic determination of the development of cardiovascular enlargement in rats
28. Heart mass and blood pressure have separate genetic determinants in the New Zealand genetically hypertensive (GHI) rat
29. Mapping of quantitative trait loci for blood pressure and cardiac mass in the rat by genome scanning of recombinant inbred strains
30. The sympathetic nervous system in human hypertension
31. 2-adrenoreceptor
32. 2-adrenergic receptor locus
33. 2010-adrenergic receptor genotype
34. Impaired cardiac contractile response to isoproterenol in the spontaneously hypertensive rat
35. Left ventricular hypertrophy in rats with renovascular hypertension: Alterations in cardiac function and adrenergic responses
36. Adenylate cyclase activity during development and reversal of cardiac hypertrophy
37. Programmed cell death and expression of the protooncogene bcl-2 in myocytes during postnatal maturation of the heart
38. Normal and abnormal consequences of apoptosis in the human heart from postnatal morphogenesis to paroxysmal arrhythmias
39. Structure and chromosomal assignment of the human cyclin G gene
40. p53 induces myocyte apoptosis via the activation of the renin-angiotensin system
41. Contribution of autosomal loci and the Y chromosome to the stress response in rat
42. Mapping of quantitative trait loci (QTL) of differential stress gene expression in rat recombinant inbred strains
43. Newborn and adult recombinant inbred strains: A tool for the search of genetic determinants of target organ damage in hypertension
44. Altered in vivo cardiovascular cell turnover in hypetension
45. Renal disease susceptibility and hypertension are under independent genetic control in the fawn-hooded rat
46. Accelerated entry of aortic smooth muscle cells from spontaneously hypertensive rats into the S phase of the cell cycle
47. Cell kinetics of aortic smooth muscle cells in long-term cultures prepared from rats raised under conventional and SPF conditions
48. Hypertension: Genes and environment
49. Cancer and hypertension: An unresolved issue
50. Cancer and hypertension: A potential for crosstalk?
51. Reflections on telomeres, growth, aging, and essential hypertension
52. Telomere length inversely correlates with pulse pressure and is highly familial
53. Developmental and tissue-specific regulation of mouse telomerase and telomere length
54. Telomere length and replicative aging in human vascular tissues