Tumor necrosis factor markers show sex-influenced association with rheumatoid arthritis

Arthritis and Rheumatism

Volumn 44, Issue 2, 2001, Pages 286-295

  Meyer, Joanne M ^a   Han, Jinfeng ^b   Moxley, George ^b  

^a MILLENNIUM PHARMACEUTICALS INC   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HLA DR ANTIGEN; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CONTROLLED STUDY; FEMALE; GENETIC SUSCEPTIBILITY; HAPLOTYPE; HLA TYPING; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; RISK FACTOR; SEX DIFFERENCE;

ALLELES; ARTHRITIS, RHEUMATOID; BIOLOGICAL MARKERS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HISTOCOMPATIBILITY TESTING; HLA-DQ ANTIGENS; HLA-DR ANTIGENS; HUMANS; LINKAGE DISEQUILIBRIUM; MALE; MICROSATELLITE REPEATS; MIDDLE AGED; PROMOTER REGIONS (GENETICS); SEX FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0035089735     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/1529-0131(200102)44:2<286::AID-ANR45>3.0.CO;2-4     Document Type: Article

References (57)

1. Prevalence of familial occurrence in patients with rheumatoid arthritis
2. Rheumatoid arthritis - Nature or nurture?
3. Mixed lymphocyte cultures in rheumatoid arthritis
4. HLA-DR4 subtype frequencies in rheumatoid arthritis indicate that DRB1 is the major susceptibility locus within the HLA class region
5. HLA DR antigens in Indian patients with rheumatoid arthritis
6. Meta-analysis reveals association between most common class II haplotype in full-heritage Native Americans and rheumatoid arthritis
7. Association of HLA-Dw16 with rheumatoid arthritis in Yakima Indians: Further evidence for the "shared epitope" hypothesis
8. Rheumatoid arthritis in Israeli Jews: Shared sequences in the third hypervariable region of DRB1 alleles are associated with susceptibility
9. HLA-DRw10 confers the highest susceptibility to rheumatoid arthritis in a Spanish population
10. The shared epitope hypothesis: An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis
11. A re-analysis of the association between rheumatoid arthritis with and without extraarticular features, HLA-DR4, and DR4 subtypes
12. HLA class II sequence polymorphisms and susceptibility to rheumatoid arthritis in Greeks: The HLA-DRβ shared-epitope hypothesis accounts for the disease in only a minority of Greek patients
13. HLA-DRB1 genes and disease severity in rheumatoid arthritis
14. Histocompatibility antigens (A, B, C, and DR) in Arabs with rheumatoid arthritis
15. Weak association between HLA-DR4 and rheumatoid arthritis in Chilean patients
16. HLA-linked rheumatoid arthritis
17. HLA rheumatoid arthritis: A combined analysis of 440 British patients
18. A multicase family study of rheumatoid arthritis in south west Ireland
19. HLA-DRB1*0401/0404 genotype and rheumatoid arthritis: Increased association in men, young age at onset, and disease severity
20. HLA-DR1 and DRw6 association in DR4-negative rheumatoid arthritis patients
21. HLA-DR alleles with naturally occurring amino acid substitutions and risk for development of rheumatoid arthritis
22. Investigating the HLA component in rheumatoid arthritis: An additive (dominant) mode of inheritance is rejected, a recessive mode is preferred
23. Both inherited HLA-haplotypes are important in the predisposition to rheumatoid arthritis
24. The genotypic distribution of shared-epitope DRB1 alleles suggests a recessive mode of inhertrance of the rheumatoid arthritis disease-susceptibility gene
25. Relative predispositional effects mode of inheritance of HLA-DRB1 alleles among community-based Caucasian females with rheumatoid arthritis
26. Investigation of the HLA component involved in rheumatoid arthritis (RA) by using the marker association-segregation chi-square (MASC) method: Rejection of the unifying-shared-epitope hypothesis
27. Genetic influence on cytokine production fatal meningococcal disease
28. Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor alpha: Relevance to genetic predisposition to systemic lupus erythematosus
29. TNF alpha - A pivotal role in rheumatoid arthritis?
30. Inhibition of the production and effects of interleukin-1 and tumor necrosis factor α in rheumatoid arthritis
31. Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis
32. Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein
33. The therapeutic effects of an engineered human anti-tumour necrosis factor alpha antibody (CDP571) in rheumatoid arthritis
34. Genetic analysis of multiplex rheumatoid arthritis families
35. Genetic variability in the tumor necrosis factor-lymphotoxin region influences susceptibility to rheumatoid arthritis
36. Primary association of tumor necrosis factor-region genetic markers with susceptibility to rheumatoid arthritis
37. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis
38. Sex influences on the penetrance of HLA shared-epitope genotypes for rheumatoid arthritis
39. Eleventh International Histocompatibility Workshop reference protocol for the HLA DNA-typing technique
40. PCR-RFLP
41. Multiplex ARMS-RFLP: A simple and rapid method for HLA-DR4 subtyping
42. Extensive genetic polymorphism in the human tumor necrosis factor region and relation to extended HLA haplotypes
43. Highly informative typing of the human TNF locus using six adjacent polymorphic markers
44. Genetic polymorphism of the human tumor necrosis factor region in insulin-dependent diabetes mellitus - Linkage disequilibrium of TNFab microsatellite alleles with HLA haplotypes
45. Tumour necrosis factor a gene polymorphisms in rheumatoid arthritis: Association with susceptibility to, or severity of, disease?
46. Relative predispositional effects of marker alleles with disease: HLA-DR alleles and Graves disease
47. The data and statistical analysis
48. American Society for Human Genetics annual meeting. 1993
49. Validation of haplotype frequency estimation methods
50. Tumor necrosis factor microsatellite haplotypes are different in male female patients with RA
51. HLA antigens and seronegative rheumatoid arthritis
52. Association of HLA-DR4/Dw4 and DR2/Dw2 with radiologic changes in a prospective study of patients with rheumatoid arthritis: Preferential relationship with HLA-Dw rather than HLA-DR specificities
53. Correlation between disease phenotype and genetic heterogeneity in rheumatoid arthritis
54. Interaction between tumor necrosis factor microsatellite polymorphisms and the HLA-DRB1 shared epitope in rheumatoid arthritis: Influence on disease outcome
55. Ancestral haplotypes: Conserved population MHC haplotypes
56. Association of tumor necrosis factor microsatellite polymorphisms with HLA-DRB1*04-bearing haplotypes in rheumatoid arthritis patients
57. Tumor necrosis factor α microsatellite polymorphism is associated with rheumatoid severity through an interaction with the HLA-DRB1 shared epitope