Studies on insulin-loaded polyester nanoparticles: Preparation and pharmacodynamics

Chinese Pharmaceutical Journal

Volumn 36, Issue 1, 2001, Pages 38-42

  Ma, L M ^a   Zhang, Q ^a   Li, Y Z ^a   Gu, Z W ^a  

^a PEKING UNIVERSITY PEOPLE S HOSPITAL   (China)

Author keywords

Hypoglycemic effect; Insulin; Nanoparticles; Poly( caprolactone block D, L lactide)

Indexed keywords

DRUG CARRIER; INSULIN; NANOPARTICLE; POLYCAPROLACTONE; POLYESTER;

ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG RELEASE; DRUG SYNTHESIS; EMULSION; ENCAPSULATION; EVAPORATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPOGLYCEMIA; NONHUMAN; PHARMACODYNAMICS; RAT; TRANSMISSION ELECTRON MICROSCOPY;

EID: 0035089333     PISSN: 10012494     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Recent advances on the use of biodegradable microparticles and nanoparticles in controlled drug delivery
2. Lidocaine-loaded biodegradable nanospheres. I. Optimization of the drug incorporation into the polymer matrix
3. Formulation of Lasparaginase-loaded poly (lactide-co-glycolide) nanoparticles: Influence of polymer properties on enzyme loading, activity and in vitro release
4. PLGA nanoparticles prepared by nanoprecipitation: Drug loading and release studies of a water soluble drug
5. In vitro drug release behavior of D, L-lactide/glycolide copolymer (PLGA) nanospheres with nafarelin acetate prepared by a novel spontaneous emulsification solvent diffusion method
6. Nano-and microparticles for the delivery of polypeptides and proteins