Precious things come in little packages

Journal of Molecular Microbiology and Biotechnology

Volumn 3, Issue 2, 2001, Pages 155-162

  Schuldiner, S ^a   Granot, D ^a   Mordoch, S S ^a   Ninio, S ^a   Rotem, D ^a   Soskin, M ^a   Yerushalmi, H ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ACRIFLAVINE; ANTIPORTER; BENZALKONIUM; CARBOXYLIC ACID DERIVATIVE; CYSTEINE; ETHIDIUM BROMIDE; GLUTAMINE; GLYCOPROTEIN P; TETRAPHENYLPHOSPHONIUM;

ALPHA HELIX; AMINO ACID SEQUENCE; BACTERIAL MEMBRANE; BINDING AFFINITY; CELL MEMBRANE; CONFERENCE PAPER; DRUG BINDING SITE; DRUG TRANSPORT; ESCHERICHIA COLI; FOURIER ANALYSIS; HYDROPHOBICITY; LIGAND BINDING; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; MOLECULAR SIZE; MULTIDRUG RESISTANCE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PH; PROTEIN SECONDARY STRUCTURE; PROTON MOTIVE FORCE; PROTON TRANSPORT; SEQUENCE HOMOLOGY; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANTIPORTERS; BACTERIAL PROTEINS; DRUG RESISTANCE, MULTIPLE; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; MACROMOLECULAR SUBSTANCES; MEMBRANE PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN STRUCTURE, SECONDARY; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0035088487     PISSN: 14641801     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (55)

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2. Identification of acetylcholine receptor channel-lining residues in the entire M2 segment of the a-subunit: Implications for the secondary structure and for the locations of the gate and a selectivity filter
3. Amino acid residues lining the chloride channel of the cystic fibrosis transmembrane conductance regulator
4. Determining the secondary structure and orientation of EmrE, a multi-drug transporter, indicates a transmembrane four helix bundle
5. Inactivation of antibiotics and the dissemination of resistance genes
6. ATP-dependent transport systems in bacteria and humans - Relevance to cystic fibrosis and multidrug resistance
7. Cys-scanning mutagenesis: A novel approach to structure- function relationships in polytopic membrane proteins
8. Helical structure and folding of subunit c of F1Fo ATP synthase
9. Determination of local protein structure by spin label difference 2D NMR: The region neighboring Asp61 of subunit c of the F1F0 ATP synthase
10. Biochemistry of multidrug resistance mediated by the multidrug transporter
11. A novel multicopy suppressor of a groEL mutation includes two nested open reading frames transcribed from different promoters
12. Evolution of transmembrane transport: Relationships between transport proteins for sugars, carboxylate compounds, antibiotics and antiseptics
13. A staphylococcal multidrug resistance gene product is a member of a new protein family
14. Bacterial multidrug resistance is due to a single membrane protein which functions as a drug pump
15. Drug excretion mediated by a new prototype of polyspecific transporter
16. A broad-specificity multidrug efflux pump requiring a pair of homologous SMR-type proteins
17. Cysteine-scanning mutagenesis around transmembrane segment III of Tn10-encoded metal-tetracycline/H+ antiporter
18. Determination of a transmembrane segment using cysteine- scanning mutants of transposon Tn10-encoded metal-tetracycline/H+ antiporter
19. Site-directed chemical modification of cystein-scanning mutants as to transmembrane segment II and its flanking regions of the Tn10-encoded metal-tetracycline/H+ antiporter reveals a transmembrane water-filled channel
20. Progress toward an explicit mechanistic model for the light-driven pump, bacteriorhodopsin
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23. A two-component multidrug efflux pump, EbrAB, in Bacillus subtilis
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26. Characterization of the fundamental protein ligand requirements of [4Fe-4S](2+/+) clusters with sixteen amino acid maquettes
27. A membrane-embedded glutamate is required for ligand binding to the multidrug transporter EmrE
28. Natural functions of bacterial multidrug transporters
29. Prevention of drug access to bacterial targets: Permeability barrier and active efflux
30. Backbone dynamics of (1-71) bacterioopsin studied by two-dimensional 1H-15N NMR spectroscopy
31. pH homeostasis in bacteria
32. Molecular chracterization of the staphylococcal multidrug resistance export protein QacC
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35. Nucleotide sequence of the ethidium efflux gene from Escherichia coli
36. Structural changes linked to proton translocation by subunit c of the ATP synthase
37. Resistance gene capture
38. Phosphatidylcholine transclocase: A physiological role for the mdr2 gene
39. Unraveling the mechanism of the lactose permeases of Escherichia coli
40. Disruption of the mouse mdr1a P-glycoprotein gene leads to a defficiency in the blood-brain barrier and to increased sensity to drugs
41. Emre, the smallest ion coupled transporter, provides a unique paradigm for structure function studies
42. Vesicular neurotransmitter transporters: From bacteria to human
43. NMR investigation of the multidrug transporter EmrE, an integral membrane protein
44. Scanning cysteine accessibility of EmrE, an H+-coupled multidrug transporter from escherichia coli, reveals a hydrophobic pathway for solutes
45. Topology of the region surrounding Glu(681) of human AE1 protein, the erythrocyte anion exchanger
46. Amino acids lining the channel of the α-aminobutyric acid type a receptor identified by cysteine substitution
47. Identification of a residue in the translocation pathway of a membrane carrier
48. Residues in the pathway through a membrane transporter
49. EmrE, an Escherichia coli 12-kDa multidrug transporter, exchanges toxic cations and H+ and is soluble in organic solvents
50. Negative dominance studies demonstrate the oligomeric structure of emre, a multidrug antiporter from escherichia coli
51. A common binding site for substrates and protons in EmrE, an ion-coupled multidrug transporter
52. An essential glutamyl residue in EmrE, a multidrug antiporter from Escherichia coli
53. A single-carboxyl mutant of the multidrug transporter EmrE is fully functional
54. Structural basis of multidrug recognition by BmrR, a transcription activator of a multidrug transporter