A low-molecular-weight fraction of human seminal plasma activates adenylyl cyclase and induces caspase 3-independent apoptosis in prostatic epithelial cells by decreasing mitochondrial potential and Bcl-2/Bax ratio

FASEB Journal

Volumn 15, Issue 3, 2001, Pages 673-683

  Untergasser, G ^a   Rumpold, H ^a   Plas, E ^b   Madersbacher, S ^c   Berger, P ^a  

^a ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

^b LUDWIG BOLTZMANN INSTITUTE FOR LUNG VASCULAR RESEARCH   (Austria)

^c UNIVERSITY OF VIENNA   (Austria)

Author keywords

Aging; cAMP; HPLC analysis; Mitochondria; p53; Par 4; SMP

Indexed keywords

ADENYLATE CYCLASE; CASPASE 3; CYCLIC AMP; MEMBRANE RECEPTOR; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INDUCTION; GEL PERMEATION CHROMATOGRAPHY; HUMAN; HUMAN CELL; MALE; MALE FERTILITY; MITOCHONDRION; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROSTATE DISEASE; PROSTATE EPITHELIUM; PROTEIN PHOSPHORYLATION; SEMINAL PLASMA; SIGNAL TRANSDUCTION; SPERM;

ADENYLATE CYCLASE; ADULT; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CASPASES; CELL SIZE; CELL SURVIVAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENZYME ACTIVATION; EPITHELIAL CELLS; HUMANS; MALE; MEMBRANE POTENTIALS; MICROSCOPY, CONFOCAL; MITOCHONDRIA; ORGANOIDS; PROSTATE; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; SEMEN; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED; ULTRAVIOLET RAYS;

EID: 0035082217     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.00-0270com     Document Type: Article

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