Intrahepatic metastasis by orthotopic implantation of a fragment of murine hepatoma and its related molecules

Tumor Biology

Volumn 22, Issue 3, 2001, Pages 154-161

  Sawada, Shigeaki ^a,b   Murakami, Koji ^a   Yamaura, Takeshi ^a   Sakamoto, Takashi ^b   Ogawa, Katsuhiro ^c   Tsukada, Kazuhiro ^b   Saiki, Ikuo ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

^b TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY   (Japan)

^c ASAHIKAWA MEDICAL COLLEGE   (Japan)

Author keywords

Fragment; Hepatoma; Implantation, orthotopic; Metastasis, intrahepatic; MMP 9; MT1 MMP

Indexed keywords

GELATINASE B; MATRIX METALLOPROTEINASE; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INVASION; CANCER RECURRENCE; CANCER SURVIVAL; CANCER TRANSPLANTATION; CELL ADHESION; CELL MIGRATION; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; LIVER CELL CARCINOMA; LIVER METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0035080480     PISSN: 10104283     EISSN: None     Source Type: Journal    
DOI: 10.1159/000050610     Document Type: Article

References (35)

1. Therapeutic results of resection, transcatheter arterial embolization and percutaneous transhepatic ethanol injection in 3225 patients with hepatocellular carcinoma: A retrospective multicenter study
2. Vascular changes and hemodynamics in hepatocellular carcinoma
3. Intrahepatic metastasis in hepatocellular carcinoma: The role of the portal vein as an efferent vessel
4. Growth and spread of hepatocellular carcinoma
5. The Ernst W. Bertner Memorial Award Lecture: The evolution of biological heterogeneity in metastatic neoplasmas
6. Tumor cell instability, diversification, and progression to the metastatic phenotype: From oncogene to oncofetal expression
7. 'Seed and soil' revisited: Mechanisms of site specific metastasis
8. Tumor invasion and the extracellular matrix
9. Basement membrane and the invasive activity of metastatic tumor cells
10. Laminin and fibronectin promote the haptotactic migration of B16 mouse melanoma cells in vitro
11. Rationale and methods for the use of nude mice to study the biology and therapy of human cancer metastasis
12. E-cadherin is involved in the intrahepatic metastasis of hepatocellular carcinoma
13. Hepatocellular carcinoma in an orthotopic mouse model metastasizes intrahepatically in cirrhotic but not in normal liver
14. β-catenin mutations are frequent in hepatocellular carcinomas but absent in adenomas induced by diethylnitrosamine in B6C3F1 mice
15. Inhibition of tumor cell invasion by Ubenimex (Bestatin) in vitro
16. A modified and convenient method for assessing tumor cell invasion and migration and its application to screening for inhibitors
17. Inhibition of lung metastasis by synthetic and recombinant fragments of human fibronectin with functional domains
18. Mesangial cells from transgenic mice with progressive glomerulosclerosis exhibit stable, phenotypic changes including undetectable MMP-9 and increased type IV collagen
19. Identification of cytokine and adhesion molecule mRNA in murine lung tissue and isolated cells and eosinophils by semi-quantitative reverse transcriptase-polymerase chain reaction
20. Electrophoretic analysis of plasminogen activators in polyacrylamide gels containing sodium dodecyl sulfate and copolymerized substrates
21. Concomitant expression of hepatocyte growth factor/scatter factor and the receptor c-MET in human myeloma cell lines
22. Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation
23. Biology and biochemistry of proteinases in tumor invasion
24. Relation of enhanced secretion of active matrix metalloproteinases with tumor spread in human hepatocellular carcinoma
25. Overexpression of matrix metalloproteinase 9 gene in hepatocellular carcinoma with invasive potential
26. Membrane-type matrix metalloproteinase-1 (MT1-MMP) gene is overexpressed in highly invasive hepatocellular carcinoma
27. A matrix metalloproteinase expressed on the surface of invasive tumor cells
28. Membrane type 1 matrix metalloproteinase digests interstitial collagens and other extracellular matrix macromolecules
29. Tumor invasion and metastases role of the extracellular matrix: Rhoads Memorial Award Lecture
30. Biochemical interactions of tumor cells with the basement membrane
31. Tumor cell interactions with the extracellular matrix during invasion and metastasis
32. Matrix metalloproteinase-9 (92 kDa gelatinase/type IV collagenase) from U937 monoblastoid cells: Correlation with cellular invasion
33. Matrix metalloproteinase 9 (92-kDa gelatinase/type IV collagenase) from HT1080 human fibrosarcoma cells. Purification and activation of the precursor and enzymic properties
34. Localization of matrix metalloproteinase 9 (92-kilodalton gelatinase/type IV collagenase = gelatinase B) in osteoclasts: Implication for bone resorption
35. Invasiveness of hepatocellular carcinoma cell lines: Contribution of membrane-type 1 matrix metalloproteinase