Human placenta as a source of neuroendocrine factors

Biology of the Neonate

Volumn 79, Issue 3-4, 2001, Pages 150-156

  Reis, Fernando M ^a   Florio, Pasquale ^a   Cobellis, Luigi ^a   Luisi, Stefano ^a   Severi, Filiberto M ^a   Bocchi, Caterina ^a   Picciolini, Enrico ^a   Centini, Giovanni ^a   Petraglia, Felice ^a  

^a UNIVERSITY OF SIENA   (Italy)

Author keywords

Gestational diseases; Labor; Neurohormones; Placenta; Pregnancy

Indexed keywords

CHORIONIC GONADOTROPIN; HYPOPHYSIS HORMONE; NEUROHORMONE; SEX HORMONE;

AUTOCRINE EFFECT; CONFERENCE PAPER; ENDOCRINE FUNCTION; FETUS GROWTH; FETUS MATURITY; HORMONAL REGULATION; HORMONE RELEASE; HORMONE SYNTHESIS; LABOR; NEUROENDOCRINE SYSTEM; NIDATION; PARACRINE SIGNALING; PLACENTA; PREGNANCY; PREGNANCY COMPLICATION; PRIORITY JOURNAL; UTERUS BLOOD FLOW;

FEMALE; GONADOTROPINS; HUMAN GROWTH HORMONE; HUMANS; INSULIN-LIKE GROWTH FACTOR I; LEPTIN; NEUROPEPTIDE Y; NEUROPEPTIDES; OXYTOCIN; PLACENTA; PLACENTAL LACTOGEN; PREGNANCY; PROLACTIN; THYROTROPIN-RELEASING HORMONE;

EID: 0035079596     PISSN: 00063126     EISSN: None     Source Type: Journal    
DOI: 10.1159/000047083     Document Type: Conference Paper

References (70)

1. Bajoria R, Babawale M: Ontogeny of endogenous secretion of immunoreactive-thyrotropin releasing hormone by the human placenta. J Clin Endocrinol Metab 1998;83:4148-4155.
2. Bajoria R, Peek MJ, Fisk NM: Maternal-to-fetal transfer of thyrotropin-releasing hormone in vivo. Am J Obstet Gynecol 1998;178:264-269.
3. Hershman JM, Starnes WR: Extraction and characterization of a thyrotropic material from the human placenta. J Clin Invest 1969;48:923-929.
4. Kanazawa S, Nakamura A, Saida K, Tojo S: Placento-thyroidal relationship in normal pregnancy. Acta Obstet Gynecol Scand 1976;55:201-205.
5. Josimovich JB, MacLaren JA: Presence in human placenta and term serum of highly lactogenic substance immunologically related to pituitary growth hormone. Endocrinology 1962;71:209-215.
6. Jaffe RB: Neuroendocrine-metabolic regulation of pregnancy; in Yen SSC, Jaffe RB, Barbieri RL (eds): Reproductive Endocrinology, ed 4. Philadelphia, W.B. Saunders, 1998, pp 751-784.
7. Boguszewski CL, Svensson PA, Jansson T, Clark R, Carlsson LM, Carlsson B: Cloning of two novel growth hormone transcripts expressed in human placenta. J Clin Endocrinol Metab 1998;83:2878-2885.
8. Alsat E, Guibourdenche J, Couturier A, Evain Brion D: Physiological role of human placental growth hormone. Mol Cell Endocrinol 1998;140: 121-127.
9. Nogues N, Del Rio JA, Perez Riba M, Soriano E, Flavell RA, Boronat A: Placenta-specific expression of the rat growth hormone-releasing hormone gene promoter in transgenic mice. Endocrinology 1997;138:3222-3227.
10. Gaylinn BD: Molecular and cell biology of the growth hormone-releasing hormone receptor. Growth Horm IGF Res 1999;9(suppl A):37-44.
11. Reis FM, Fadalti M, Florio P, Petraglia F: Putative role of corticotropin-releasing factor in the mechanisms of human parturition. J Soc Gynecol Investig 1999;6:109-119.
12. Karteris E, Grammatopoulos D, Dai Y, Olah KB, Ghobara TB, Easton A, Hillhouse EW: The human placenta and fetal membranes express the corticotropin-releasing hormone receptor 1alpha (CRH-1alpha) and the CRH-C variant receptor. J Clin Endocrinol Metab 1998;83:1376-1379.
13. Florio P, Franchini A, Reis FM, Palumbo M, Ottaviani E, Petraglia F: Human placenta, chorion, amnion and decidua express different variants of corticotropin-releasing factor receptor messenger RNA. Placenta 2000;21:32-37.
14. Petraglia F, Florio P, Gallo R, Simoncini T, Saviozzi M, Di Blasio AM, Vaughan J, Vale W: Human placenta and fetal membranes express human urocortin mRNA peptide. J Clin Endocrinol Metab 1996;81:3807-3810.
15. Watanabe F, Oki Y, Ozawa M, Masuzawa M, Iwabuchi M, Yoshimi T, Nishiguchi T, Iino K, Sasano H: Urocortin in human placenta and maternal plasma. Peptides 1999;20:205-209.
16. Petraglia F, Florio P, Benedetto C, Marozio L, Di Blasio AM, Ticconi C, Piccione E, Luisi S, Genazzani AR, Vale W: Urocortin stimulates placental ACTH and prostaglandin release and myometrial contractility in vitro. J Clin Endocrinol Metab 1999;84:1420-1423.
17. Leitch IM, Boura AL, Botti C, Read MA, Walters WA, Smith R: Vasodilator actions of urocortin and related peptides in the human perfused placenta in vitro. J Clin Endocrinol Metab 1998;83:4510-4513.
18. Waddell BJ, Burton PJ: Release of bioactive ACTH by perifused human placenta at early and late gestation. J Endocrinol 1993;136:345-353.
19. Smith R, Thomson M: Neuroendocrinology of the hypothalamo-pituitary-adrenal axis in pregnancy and the puerperium. Baillières Clin Endocrinol Metab 1991;5:167-186.
20. Cooper ES, Greer IA, Brooks AN: Placental proopiomelanocortin gene expression, adrenocorticotropin tissue concentrations, and immunostaining increase throughout gestation and are unaffected by prostaglandins, antiprogestins, or labor. J Clin Endocrinol Metab 1996;81:4462-4469.
21. Barnea ER, Lavy G, Fakih H, Decherney AH: The role of ACTH in placental steroidogenesis. Placenta 1986;7:307-313.
22. Clifton VL, Read MA, Boura AL, Robinson PJ, Smith R: Adrenocorticotropin causes vasodilatation in the human fetal-placental circulation. J Clin Endocrinol Metab 1996;81:1406-1410.
23. Muyan M, Boime I: Secretion of chorionic gonadotropin from human trophoblasts. Placenta 1997; 18:237-241.
24. Grun JP, Meuris S, De Nayer P, Glinoer D: The thyrotrophic role of human chorionic gonadotrophin (hCG) in the early stages of twin (versus single) pregnancies. Clin Endocrinol (Oxf) 1997;46: 719-725.
25. Wolfahrt S, Kleine B, Rossmanith WG: Detection of gonadotrophin releasing hormone and its receptor mRNA in human placental trophoblasts using in-situ reverse transcription-polymerase chain reaction. Mol Hum Reprod 1998;4:999-1006.
26. Siler-Khodr TM, Khodr GS: Dose response analysis of GnRH stimulation of hCG release from human term placenta. Biol Reprod 1981;25:353-358.
27. Iwashita M, Kudo Y, Shinozaki Y, Takeda Y: Gonadotropin-releasing hormone increases serum human chorionic gonadotropin in pregnant women. Endocr J 1993;40:539-544.
28. Lin LS, Roberts VJ, Yen SS: Expression of human gonadotropin-releasing hormone receptor gene in the placenta and its functional relationship to human chorionic gonadotropin secretion. J Clin Endocrinol Metab 1995;80:580-585.
29. Boyle TA, Belt-Davis DI, Duello TM: Nucleotide sequence analyses predict that human pituitary and human placental gonadotropin-releasing hormone receptors have identical primary structures. Endocrine 1998;9:281-287.
30. Petraglia F, Woodruff TK, Botticelli G, Botticelli A, Genazzani AR, Mayo KE, Vale W: Gonadotropin-releasing hormone, inhibin, and activin in human placenta: Evidence for a common cellular localization. J Clin Endocrinol Metab 1992;74: 1184-1188.
31. Steele GL, Currie WD, Yuen BH, Jia XC, Perlas E, Leung PC: Acute stimulation of human chorionic gonadotropin secretion by recombinant human activin-A in first trimester human trophoblast. Endocrinology 1993;133:297-303.
32. Petraglia F, Vaughan J, Vale W: Inhibin and activin modulate the release of gonadotropin-releasing hormone, human chorionic gonadotropin, and progesterone from cultured human placental cells. Proc Natl Acad Sci USA 1989;86:5114-5117.
33. Qu J, Thomas K: Inhibin and activin production in human placenta. Endocr Rev 1995;16:485-507.
34. Petraglia F, Sawchenko P, Lim AT, Rivier J, Vale W: Localization, secretion, and action of inhibin in human placenta. Science 1987;237:187-189.
35. Petraglia F: Inhibin, activin and follistatin in the human placenta - a new family of regulatory proteins. Placenta 1997;18:3-8.
36. Wu WX, Brooks J, Millar MR, Ledger WL, Saunders PT, Glasier AF, McNeilly AS: Localization of the sites of synthesis and action of prolactin by immunocytochemistry and in-situ hybridization within the human utero-placental unit. J Mol Endocrinol 1991;7:241-247.
37. Wu WX, Brooks J, Glasier AF, McNeilly AS: The relationship between decidualization and prolactin mRNA and production at different stages of human pregnancy. J Mol Endocrinol 1995;14:255-261.
38. Frasor J, Gaspar CA, Donnelly KM, Gibori G, Fazleabas AT: Expression of prolactin and its receptor in the baboon uterus during the menstrual cycle and pregnancy. J Clin Endocrinol Metab 1999;84:3344-3350.
39. Ben-Jonathan N, Mershon JL, Allen DL, Steinmetz RW: Extrapituitary prolactin: Distribution, regulation, functions, and clinical aspects. Endocr Rev 1996;17:639-669.
40. Chibbar R, Miller FD, Mitchell BF: Synthesis of oxytocin in amnion, chorion, and decidua may influence the timing of human parturition. J Clin Invest 1993;91:185-192.
41. Chibbar R, Wong S, Miller FD, Mitchell BF: Estrogen stimulates oxytocin gene expression in human chorio-decidua. J Clin Endocrinol Metab 1995;80: 567-572.
42. Takemura M, Kimura T, Nomura S, Makino Y, Inoue T, Kikuchi T, Kubota Y, Tokugawa Y, Nobunaga T, Kamiura S: Expression and localization of human oxytocin receptor mRNA and its protein in chorion and decidua during parturition. J Clin Invest 1994;93:2319-2323.
43. Florio P, Lombardo M, Gallo R, Di Carlo C, Sutton S, Genazzani AR, Petraglia F: Activin A, corticotropin-releasing factor and prostaglandin F2 alpha increase immunoreactive oxytocin release from cultured human placental cells. Placenta 1996;17:307-311.
44. Jin L, Burguera BG, Couce ME, Scheithauer BW, Lamsan J, Eberhardt NL, Kulig E, Lloyd RV: Leptin and leptin receptor expression in normal and neoplastic human pituitary: Evidence of a regulatory role for leptin on pituitary cell proliferation. J Clin Endocrinol Metab 1999;84:2903-2911.
45. Sivan E, Whittaker PG, Sinha D, Homko CJ, Lin M, Reece EA, Boden G: Leptin in human pregnancy: The relationship with gestational hormones. Am J Obstet Gynecol 1998;179:1128-1132.
46. Jaquet D, Leger J, Levy Marchal C, Oury JF, Czernichow P: Ontogeny of leptin in human fetuses and newborns: Effect of intrauterine growth retardation on serum leptin concentrations. J Clin Endocrinol Metab 1998;83:1243-1246.
47. Mise H, Sagawa N, Matsumoto T, Yura S, Nanno H, Itoh H, Mori T, Masuzaki H, Hosoda K, Ogawa Y, Nakao K: Augmented placental production of leptin in preeclampsia: Possible involvement of placental hypoxia. J Clin Endocrinol Metab 1998; 83:3225-3229.
48. Yura S, Sagawa N, Mise H, Mori T, Masuzaki H, Ogawa Y, Nakao K: A positive umbilical venousarterial difference of leptin level and its rapid decline after birth. Am J Obstet Gynecol 1998;178: 926-930.
49. Bodner J, Ebenbichler CF, Wolf HJ, Muller-Holzner E, Stanzl U, Gander R, Huter O, Patsch JR: Leptin receptor in human term placenta: In situ hybridization and immunohistochemical localization. Placenta 1999;20:677-682.
50. Henson MC, Swan KF, O'Neil JS: Expression of placental leptin and leptin receptor transcripts in early pregnancy and at term. Obstet Gynecol 1998; 92:1020-1028.
51. Graf AH, Hutter W, Hacker GW, Steiner H, Anderson V, Staudach A, Dietze O: Localization and distribution of vasoactive neuropeptides in the human placenta. Placenta 1996;17:413-421.
52. Graham CH, Watson JD, Blumenfeld AJ, Pang SC: Expression of atrial natriuretic peptide by third-trimester placental cytotrophoblasts in women. Biol Reprod 1996;54:834-840.
53. Petraglia F, Calza L, Giardino L, Sutton S, Marrama P, Rivier J, Genazzani AR, Vale W: Identification of immunoreactive neuropeptide-Y in human placenta: Localization, secretion, and binding. Endocrinology 1989;124:2016-2022.
54. Petraglia F, Coukos G, Battaglia C, Bartolotti A, Volpe A, Nappi C, Segre A, Genazzani AR: Plasma and amniotic fluid immunoreactive neuropeptide-Y level changes during pregnancy, labor, and at parturition. J Clin Endocrinol Metab 1989;69: 324-328.
55. Di Iorio R, Marinoni E, Letizia C, Villaccio B, Alberini A, Cosmi EV: Adrenomedullin production is increased in normal human pregnancy. Eur J Endocrinol 1999;140:201-206.
56. Marinoni E, Di Iorio R, Letizia C, Villaccio B, Scucchi L, Cosmi EV: Immunoreactive adrenomedullin in human fetoplacental tissues. Am J Obstet Gynecol 1998;179:784-787.
57. Poisner AM: The human placental renin-angiotensin system. Front Neuroendocrinol 1998;19:232-252.
58. Li X, Shams M, Zhu J, Khalig A, Wilkes M, Whittle M, Barnes N, Ahmed A: Cellular localization of AT1 receptor mRNA and protein in normal placenta and its reduced expression in intrauterine growth restriction. Angiotensin II stimulates the release of vasorelaxants. J Clin Invest 1998;101: 442-454.
59. Holst N, Oian P, Aune B, Jenssen TG, Burhol PG: Increased plasma levels of vasoactive intestinal polypeptide in pre-eclampsia. Br J Obstet Gynaecol 1991;98:803-806.
60. Dombroski RA, Casey ML, MacDonald PC: 5-Alpha-dihydroprogesterone formation in human placenta from 5alpha-pregnan-3beta/alpha-ol-20-ones and 5-pregnan-3beta-yl-20-one sulfate. J Steroid Biochem Mol Biol 1997;63:155-163.
61. Le Goascogne C, Eychenne B, Tonon MC, Lachapelle F, Baumann N, Robel P: Neurosteroid progesterone is up-regulated in the brain of jimpy and shiverer mice. Glia 2000;29:14-24.
62. Luisi S, Petraglia F, Benedetto C, Nappi RE, Bernardi F, Fadalti M, Reis FM, Luisi M, Genazzani AR: Serum allopregnanolone levels in pregnant women: Changes during pregnancy, at delivery, and in hypertensive patients. J Clin Endocrinol Metab 2000;85:2429-2433.
63. Lofgren M, Holst J, Backstrom T: Effects in vitro of progesterone and two 5 alpha-reduced progestins, 5 alpha-pregnane-3,20-dione and 5 alpha-pregnane-3 alpha-ol-20-one, on contracting human myometrium at term. Acta Obstet Gynecol Scand 1992;71:28-33.
64. Bzoskie L, Yen J, Tseng YT, Blount L, Kashiwai K, Padbury JF: Human placental norepinephrine transporter mRNA: Expression and correlation with fetal condition at birth. Placenta 1997;18: 205-210.
65. Vaillancourt C, Petit A, Belisle S: Expression of human placental D2-dopamine receptor during normal and abnormal pregnancies. Placenta 1998; 19:73-80.
66. Kenney SP, Kekuda R, Prasad PD, Leibach FH, Devoe LD, Ganapathy V: Cannabinoid receptors and their role in the regulation of the serotonin transporter in human placenta. Am J Obstet Gynecol 1999;181:491-497.
67. Nguyen TT, Tseng YT, McGonnigal B, Stabila JP, Worrell LA, Saha S, Padbury JF: Placental biogenic amine transporters: In vivo function, regulation and pathobiological significance. Placenta 1999; 20:3-11.
68. Falkay G, Kovacs L: Expression of two alpha 2-adrenergic receptor subtypes in human placenta: Evidence from direct binding studies. Placenta 1994;15:661-668.
69. Manyonda IT, Slater DM, Fenske C, Hole D, Choy MY, Wilson C: A role for noradrenaline in preeclampsia: Towards a unifying hypothesis for the pathophysiology. Br J Obstet Gynaecol 1998;105: 641-648.
70. Lambert-Messerlian GM, Silver HM, Petraglia F, Luisi S, Pezzani I, Maybruck WM, Hogge WA, Hanley-Yanez K, Roberts JM, Neveux LM, Canick JA: Second-trimester levels of maternal serum human chorionic gonadotropin and inhibin a as predictors of preeclampsia in the third trimester of pregnancy. J Soc Gynecol Investig 2000;7:170-174.