Active oligonucleotides incorporating alkylating an agent as potential sequence- and base selective modifier of gene expression

European Journal of Pharmaceutical Sciences

Volumn 13, Issue 1, 2001, Pages 43-51

  Sasaki, S ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

2 amino 6 vinylpurine; Alkylation; Antigene; Antisense; Cross linking; Inducible reactivity; Invasion of duplex; Oligonucleotide

Indexed keywords

ACIDITY; ALKYLATION; ENZYME INHIBITION; VINYL RESINS;

CROSS-LINKING AGENTS;

GENES;

2 AMINO 6 VINYLPURINE; ALKYLATING AGENT; ANTISENSE OLIGONUCLEOTIDE; CYTIDINE; DEOXYRIBOSE; DOUBLE STRANDED DNA; NUCLEIC ACID BASE; NUCLEOSIDE DERIVATIVE; OLIGONUCLEOTIDE; UNCLASSIFIED DRUG;

BIOTECHNOLOGY; CHEMICAL REACTION; CROSS LINKING; DNA ALKYLATION; DNA CROSS LINKING; DNA SEQUENCE; GENE CONTROL; GENE EXPRESSION; PRIORITY JOURNAL; REVIEW;

ALKYLATING AGENTS; AZIRIDINES; CROSS-LINKING REAGENTS; CYCLOPROPANES; GENE EXPRESSION; NUCLEOSIDES; OLIGONUCLEOTIDES; PURINES; VINYL COMPOUNDS;

EID: 0035079294     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-0987(00)00206-2     Document Type: Review

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