SCOPUS 정보 검색 플랫폼

Volumn 24, Issue 1, 2001, Pages 87-94

Chemotherapy in colorectal cancer - Which therapy is justified in elderly patients?;Chemotherapie des kolorektalen karzinoms - Welche therapie ist bei älteren patienten gerechtfertigt?

(4) Honecker, F a Wedding, U b Kolb, G c Bokemeyer, C a

a UNIVERSITY HOSPITAL TÜBINGEN (Germany)

b FRIEDRICH SCHILLER UNIVERSITY JENA (Germany)

c ST BONIFATIUS HOSPITAL (Germany)

Author keywords

Chemotherapy; Colorectal cancer; Elderly patients

Indexed keywords

ALPHA2B INTERFERON; ANTINEOPLASTIC AGENT; CAPECITABINE; DOXIFLURIDINE; FLUOROPYRIMIDINE; FLUOROURACIL; FOLINIC ACID; IRINOTECAN; MITOMYCIN C; OXALIPLATIN; PRODRUG; RALTITREXED; UFT;

AGED; CANCER ADJUVANT THERAPY; CANCER CHEMOTHERAPY; CANCER PALLIATIVE THERAPY; COLORECTAL CANCER; DIARRHEA; DRUG EFFICACY; HUMAN; MAJOR CLINICAL STUDY; NAUSEA; NEUROTOXICITY; REVIEW; THROMBOCYTOPENIA;

AGED; ANTINEOPLASTIC AGENTS; CAMPTOTHECIN; CHEMOTHERAPY, ADJUVANT; CLINICAL TRIALS; COLORECTAL NEOPLASMS; DOSE-RESPONSE RELATIONSHIP, DRUG; FLUOROURACIL; GERIATRIC ASSESSMENT; HUMANS; ORGANOPLATINUM COMPOUNDS; RADIOTHERAPY, ADJUVANT;

EID: 0035077182 PISSN: 0378584X EISSN: None Source Type: Journal
DOI: 10.1159/000050289 Document Type: Review

Times cited : (12)

References (50)

1
- 0034656999
- The annual report to the nation on the status of cancer, 1973-1997, with a special section on colon cancer
- (2000) Cancer , vol.88 , pp. 2398-2424
- Ries, L.A.G.¹ Wingo, P.A.² Miller, D.S.³ Howe, H.L.⁴ Weir, H.K.⁵ Rosenberg, H.M.⁶ Vernon, S.W.⁷ Cronin, K.⁸ Edwards, B.K.⁹

2
- 0025274429
- Cancer in the elderly: Why so badly treated?
- (1990) Lancet , vol.335 , pp. 1020-1022
- Fentiman, I.S.¹ Tirelli, U.² Monfardini, S.³ Schneider, M.⁴ Festen, J.⁵ Cognetti, F.⁶ Aapro, M.S.⁷

3
- 0001765095
- Screening for colorectal cancer: Guide to clinical preventive services
- (2000) JAGS , vol.48 , pp. 333-335

4
- 0028956045
- Fluorouracil plus levamisole as effective adjuvant therapy after resection of stage III colon carcinoma: A final report
- (1995) Ann Intern Med , vol.122 , pp. 321-326
- Moertel, C.G.¹ Fleming, T.R.² MacDonald, J.S.³ Haller, D.G.⁴ Laurie, J.A.⁵ Tangen, C.M.⁶ Ungerleider, J.S.⁷ Emerson, W.A.⁸ Tormey, D.C.⁹ Glick, J.H.¹⁰ Veeder, M.H.¹¹ Mailliard, J.A.¹²

5
- 0031982505
- Prospectively randomized trial of postoperative adjuvant chemotherapy in patients with high-risk colon cancer
- (1998) J Clin Oncol , vol.16 , pp. 295-300
- O'Connell, M.J.¹ Laurie, J.A.² Kahn, M.³ Fitzgibbons, R.J.⁴ Erlichman, C.⁵ Shepherd, L.⁶ Moertel, C.G.⁷ Kocha, W.I.⁸ Pazdur, R.⁹ Sam Wieand, H.¹⁰ Rubin, J.¹¹ Vukov, A.M.¹² Donohue, J.H.¹³ Krook, J.E.¹⁴ Figueredo, A.¹⁵

6
- 0032729240
- Clinical trial to assess the relative efficacy of fluorouracil and leucovorin, fluorouracil and levamisole, and fluorouracil, leucovorin, and levamisole in patients with Dukes B and C carcinoma of the colon: Results from National Surgical Adjuvant Breast and Bowel Project C-04
- (1999) J Clin Oncol , vol.17 , pp. 3553-3559
- Wolmark, N.¹ Rockette, H.² Mamounas, E.³ Jones, J.⁴ Wieand, S.⁵ Wickerham, D.L.⁶ Bear, H.D.⁷ Atkins, J.N.⁸ Dimitrov, N.V.⁹ Glass, A.G.¹⁰ Fisher, E.R.¹¹ Fisher, B.¹²

7
- 0003220611
- Survey-based analysis of treatment algorithms in colorectal cancer (CRC) in Germany discloses deficits in patient care
- abstract 964
- (2000) Proc Am Soc Clin Oncol , vol.19
- Grothey, A.¹ Büchele, T.² Feigl-Lurz, S.³ Fetscher, S.⁴ Hribaschek, T.⁵ Jamitzky, T.⁶ Ketterer, P.⁷ Siedeck, M.⁸ Templin, R.⁹ Weber, B.¹⁰ Kellermann, L.¹¹ Schmoll, H.J.¹²

8
- 0034596549
- Palliative chemotherapy for advanced colorectal cancer: Systematic review and meta-analysis
- (2000) BMJ , vol.321 , pp. 531-535

9
- 0005563271
- Colon cancer in the elderly: Evidence for major improvements in health care and survival
- (1993) Br J Cancer , vol.306 , pp. 752-755
- Arveux, I.¹ Boutron, M.C.² El Mrini, T.³ Arveux, P.⁴ Liabeuf, A.⁵ Pfittzenmeyer, P.⁶ Faivre, J.⁷

10
- 0029893529
- Substantial variation in therapy for colorectal cancer across Europe: EUROCARE analysis of cancer registry data for 1987
- (1996) Eur J Cancer , vol.32 A , pp. 831-835
- Gatta, G.¹ Sant, M.² Coebergh, J.W.³ Hakulinen, T.⁴

11
- 0033966091
- Antineoplastic chemotherapy of the older cancer patient
- (2000) Cancer Elderly , vol.14 , pp. 193-212
- Balducci, L.¹ Corcoran, M.B.²

12
- 0029809147
- Are the elderly receiving appropriate treatment for cancer?
- (1996) Ann Oncol , vol.7 , pp. 657-658
- Fentiman, I.S.¹

13
- 0033619959
- Underrepresentation of patients 65 years of age or older in cancer-treatment trials
- (1999) N Engl J Med , vol.27 , pp. 2061-2067
- Hutchins, L.F.¹ Unger, J.M.² Crowley, J.J.³ Coltman, C.A.⁴ Albain, K.S.⁵

14
- 0030049131
- Validation of a multidimensional evaluation scale for use in elderly cancer patients
- (1996) Cancer , vol.77 , pp. 395-401
- Monfardini, S.¹ Ferrucci, L.² Fratino, L.³ Del Lungo, I.⁴ Serraino, D.⁵ Zagonel, V.⁶

15
- 0016823810
- Minimal mental state. A practical method for grading the cognitive state of patients for the clinicians
- (1975) J Psychiat Res , vol.12 , pp. 189-198
- Folstein, M.F.¹ Folstein, S.E.² McHugh, P.R.³

16
- 0032697643
- Intensive versus standard chemotherapy in elderly gastric cancer patients: A retrospective analysis
- (1999) GI Cancer , vol.3 , pp. 97-101
- Cascinu, S.¹ Giordani, P.² Quattrone, A.³ Catalano, V.⁴ Antognoli, S.⁵ Piga, A.⁶ Catalano, G.⁷ Cellerino, R.⁸

17
- 0033373819
- Should chemotherapy be used as a treatment of advanced colorectal carcinoma (ACC) in patients over 70 years of age?
- (1999) Eur J Cancer , vol.12 , pp. 1640-1649
- Daniele, B.¹ Simmonds, P.D.² Best, L.Y.³ Ross, P.J.⁴ Cunningham, D.⁵

18
- 0033962905
- Comorbidity and colorectal cancer according to subsite and stage: A population-based study
- (2000) Eur J Cancer , vol.36 , pp. 95-99
- De Marco, M.F.¹ Janssen-Heijnen, M.L.² Van der Heijden, L.H.³ Coebergh, J.W.⁴

19
- 84862706826
- Kompendium für Ärzte und Sprachtherapeuten in Klinik, Rehabilitation und Geriatrie. München
- (2000) Dysphagie
- Kolb, G.¹

20
- 0033005224
- The mini nutritional assessment (MNA) and its use in grading the nutritional state of elderly patients
- (1999) Nutrition , vol.15 , pp. 116-122
- Vellas, B.¹ Guigoz, Y.² Garry, P.J.³ Nourhashemi, F.⁴ Bennahum, D.⁵ Lanque, S.⁶ Albarede, J.L.⁷

21
- 0030831715
- Polypharmacy in the older patient with cancer
- (1997) Cancer Control , vol.4 , pp. 419-428
- Corcoran, M.E.¹

22
- 0003205809
- Toxicity and cost associated with the use of 5-Fluoruoracil (5-FU) in elderly patients with colorectal carcinoma
- abstract 1732
- (2000) Proc Am Soc Clin Oncol , vol.19
- Sundararajan, V.¹ Grann, V.R.² Jacobson, J.S.³ Ahsan, H.⁴ Neugut, A.I.⁵

23
- 0033068003
- Morbidities of adjuvant chemotherapy and radiotherapy for resectable rectal cancer
- (1999) Dis Colon Rectum , vol.42 , pp. 403-418
- Ooi, B.S.¹ Tjandra, J.J.² Green, M.D.³

24
- 0000133793
- Adjuvant chemotherapy for colorectal cancer in the elderly: Population-based experience
- abstract 570
- (1993) Proc Am Soc Clin Oncol , vol.12 , pp. 195
- Brower, M.¹ Asbury, R.² Kramer, Z.³

25
- 0032792959
- Adjuvant or palliative chemotherapy for colorectal cancer in patients 70 years or older
- (1999) J Clin Oncol , vol.17 , pp. 2412-2418
- Popescu, R.A.¹ Norman, A.² Ross, P.J.³ Parikh, B.⁴ Cunningham, D.⁵

26
- 0000631412
- Adjuvant chemotherapy for colon cancer (CC) is beneficial without significantly increased toxicity in elderly patients (Pts): Results from a 3351 Pt meta-analysis
- abstract 933
- (2000) ProcAm Soc Clin Oncol , vol.19
- Sargent, D.¹ Goldberg, R.² MacDonald, J.³ Labianca, R.⁴ Haller, D.⁵ Shepard, L.⁶ Seitz, J.F.⁷ Francini, G.⁸

27
- 0031921205
- Grundlagen der internistisch-onkologischen therapie bei alten patienten mit tumorerkrankungen
- (1998) Onkologe , vol.4 , pp. 19-29
- Wedding, U.¹ Höffken, K.²

28
- 0026762968
- Expectancy or primary chemotherapy in patients with advanced asymptomatic colorectal cancer: A randomized trial
- (1992) J Clin Oncol , vol.10 , pp. 904-911

29
- 0027461840
- Randomised comparison of combination chemotherapy plus supportive care with supportive care alone in patients with metastatic colorectal cancer
- (1993) Br Med J , vol.306 , pp. 752-755
- Scheithauer, W.¹ Rosen, M.² Kornek, G.V.³ Sebesta, C.⁴ Depisch, D.⁵

30
- 0028819554
- Age and sex are independent predictors of 5-flourouracil toxicity
- (1995) Cancer , vol.75 , pp. 11-17
- Stein, B.N.¹ Petrelli, N.J.² Douglass, H.O.³ Driscoll, D.L.⁴ Arcangeli, G.⁵ Meropol, N.J.⁶

31
- 8944234341
- Toxicity and therapeutic response to chemotherapy in patients aged 70 years or older with advanced cancer
- (1996) Am J Clin Oncol , vol.19 , pp. 371-374
- Cascinu, S.¹ Del Ferro, E.² Catalano, G.³

32
- 0031823713
- Advanced colorectal cancer in the elderly: Results of consecutive trials with 5-flourouracil-based chemotherapy
- (1998) Cancer Chemother Pharmacol , vol.42 , pp. 336-340
- Chiara, S.¹ Nobile, M.T.² Vincenti, M.³ Lionetto, R.⁴ Gozza, A.⁵ Barzacchi, M.C.⁶ Sanguineti, O.⁷ Repetto, L.⁸ Rosso, R.⁹

33
- 0344109583
- Efficacy of intravenous continuous infusion of flourouracil compared with bolus administration in advanced colorectal cancer
- (1998) J Clin Oncol , vol.16 , pp. 301-308

34
- 0027954007
- Oral doxifluridine in elderly patients with metastatic colorectal cancer: A multicenter phase 2 study
- (1994) Ann Oncol , vol.5 , pp. 760-762
- Falcone, A.¹ Pfanner, E.² Ricci, S.³ Bertuccelli, M.⁴ Cianci, C.⁵ Carrai, M.⁶ De Marco, S.⁷ Ceribelli, A.⁸ Barduagni, M.⁹ Calabresi, F.¹⁰

35
- 1842409638
- Uracil and tegafur modulated with leucovorin. An effective regimen with low toxicity for the treatment of colorectal cancer in the elderly
- (1997) Cancer , vol.79 , pp. 1884-1889
- Feliu, J.¹ Gonzales Baron, M.² Espinosa, E.³ García Giron, C.⁴ De la Gandara, I.⁵ Espinosa, J.⁶ Colmenarejo, A.⁷ Jalon, J.I.⁸ Fernandez, Y.⁹ De Castro, J.¹⁰

36
- 0034086657
- Neue perspektiven mit neuen zytostatika in der behandlung des kolorektalen karzinoms
- (2000) Onkologe , vol.6 , pp. 410-419
- Büchele, T.¹ Grothey, A.² Schmoll, H.J.³

37
- 0034712536
- Irinotecan combined with fluorouracil compared with fluorouracil alone as first line treatment for metastatic colorectal cancer: A multicentre randomized trial
- (2000) Lancet , vol.355 , pp. 1041-1047
- Douillard, J.Y.¹ Cunningham, D.² Roth, A.D.³ Navarro, M.⁴ James, R.D.⁵ Karasek, P.⁶ Jandik, P.⁷ Iveson, T.⁸ Carmichael, J.⁹ Alakl, M.¹⁰ Gruia, G.¹¹ Awad, L.¹² Rougier, P.¹³

38
- 0032585232
- Randomized trial of irinotecan plus supportive care versus supportive care alone after fluorouracil failure for patients with metastatic colorectal cancer
- (1999) Lancet , vol.352 , pp. 1413-1418
- Cunningham, D.¹ Pyrhönen, S.² James, R.D.³ Punt, C.J.A.⁴ Hickish, T.F.⁵ Heikkila, R.⁶ Johannesen, T.B.⁷ Starkhammar, H.⁸ Topham, C.A.⁹ Award, L.¹⁰ Jacques, C.¹¹ Herait, P.¹²

39
- 0033004104
- Irinotecan versus infusional 5-fluorouracil: A phase III study in metastatic colorectal cancer following failure on first-line 5-fluorouracil
- (1999) Sem Oncol , vol.26 , pp. 13-20
- Van Cutsem, E.¹ Blijham, G.H.²

40
- 0345667087
- A randomized phase II trial of three different regimens of irinotecan (CPT11): A fixed dose of 350m/M2 (A), or an individual dose optimisation (B) or a risk factor optimisation (C) in patients (pts) with metastatic colorectal cancer (MCRC) previously treated with 5FU
- abstract 946
- (2000) Proc Am Soc Clin Oncol , vol.19
- Van Cutsem, E.¹ Dirix, L.² Van Laethem, J.³ Van Belle, S.⁴ Borner, M.⁵ Gonzales, M.⁶ Roth, A.⁷ Morant, R.⁸ Mathijs, R.⁹ Gruia, G.¹⁰ Noel, N.¹¹ Bleiberg, H.¹²

41
- 0033558004
- A multicenter, phase II trial of weekly irinotecan (CPT11) in patients with previously treated colorectal carcinoma
- (1999) Cancer , vol.85 , pp. 786-795
- Rothenberg, M.L.¹ Cox, J.V.² DeVore, R.F.³ Hainsworth, J.D.⁴ Pazdur, R.⁵ Rivkin, S.E.⁶ MacDonald, J.S.⁷ Geyer, C.E.⁸ Sandbach, J.⁹ Wolfs, D.L.¹⁰ Mohrland, J.S.¹¹ Elfring, G.L.¹² Miller, L.L.¹³ Von Hoff, D.D.¹⁴

42
- 0032585197
- Randomised trial of irinotecan versus flourouracil by continuous infusion after flourouracil failure in patients with metastatic colorectal cancer
- (1998) Lancet , vol.352 , pp. 1407-1412
- Rougier, P.¹ Van Cutsem, E.² Bajetta, E.³ Niederle, N.⁴ Possinger, K.⁵ Labianca, R.⁶ Navarro, M.⁷ Morant, R.⁸ Bleiberg, H.⁹ Wils, J.¹⁰ Awad, L.¹¹ Herait, P.¹² Jacques, C.¹³

43
- 0344783805
- Phase II trial of oxaliplatin as first-line chemotherapy in metastatic colorectal cancer patients
- (1998) J Clin Oncol , vol.16 , pp. 2739-2744
- Becouarn, Y.¹ Ychou, M.² Ducreux, M.³ Borel, C.⁴ Bertheault-Cvitkovic, F.⁵ Seitz, J.F.⁶ Nasca, S.⁷ Nguyen, T.D.⁸ Paillot, B.⁹ Raoul, J.L.¹⁰ Duffour, J.¹¹ Fandi, A.¹² Dupont-Andre, G.¹³ Rougier, P.¹⁴

44
- 0033874892
- Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer
- (2000) J Clin Oncol , vol.18 , pp. 2938-2947
- De Gramont, A.¹ Figer, A.² Seymour, M.³ Homerin, M.⁴ Hmissi, A.⁵ Cassidy, J.⁶ Boni, C.⁷ Cortes-Funes, H.⁸ Cervantes, A.⁹ Freyer, G.¹⁰ Papamichael, D.¹¹ Le Bail, N.¹² Louvet, C.¹³ Hendler, D.¹⁴ De Braud, F.¹⁵ Wilson, C.¹⁶ Morvan, F.¹⁷ Bonetti, A.¹⁸

45
- 0000449676
- A randomized trial of leucovorin and 5-fluorouracil with or without oxaliplatin in advanced colorectal cancer
- abstract 985
- (1998) Proc Am Soc Clin Onc , vol.17
- De Gramont, A.¹ Figer, A.² Seymour, M.³ Homerin, M.⁴ Le Bail, N.⁵ Cassidy, J.⁶ Boni, C.⁷ Cortes-Funes, H.⁸ Freyer, G.⁹ Hendler, D.¹⁰ Louvet, C.¹¹

46
- 0030888321
- Oxaliplatin with high-dose leucovorin and 5-fluorouracil 48-hour continuous infusion in pretreated metastatic colorectal cancer
- (1997) Eur J Cancer , vol.33 , pp. 214-219
- De Gramont, A.¹ Vignoud, J.² Tournigand, C.³ Louvet, C.⁴ Andre, T.⁵ Varette, C.⁶ Raymond, E.⁷ Moreau, S.⁸ Le Bail, N.⁹ Krulik, M.¹⁰

47
- 0033989203
- Phase III multicenter randomized trial of oxaliplatin added to chronomodulated fluorouracil-leucovorin as first-line treatment of metastatic colorectal cancer
- (2000) J Clin Oncol , vol.18 , pp. 136-147
- Giacchetti, S.¹ Perpoint, B.² Zidani, R.³ Le Bail, N.⁴ Faggiuolo, R.⁵ Focan, C.⁶ Chollet, P.⁷ Llory, J.F.⁸ Letourneau, Y.⁹ Coudert, B.¹⁰ Bertheaut-Cvitkovic, F.¹¹ Larregain-Fournier, D.¹² Le Rol, A.¹³ Walter, S.¹⁴ Adam, R.¹⁵ Misset, J.L.¹⁶ Levi, F.¹⁷

48
- 0034006524
- Clinical pharmacokinetics of oxaliplatin: A critical review
- (2000) Clin Cancer Res , vol.6 , pp. 1205-1218
- Graham, M.A.¹ Lockwood, G.F.² Greenslade, D.³ Brienza, S.⁴ Bayssas, M.⁵ Gamelin, E.⁶

49
- 0000769177
- Supportive maßnahmen bei der chemotherapie älterer patienten
- (1998) Arzneimitteltherapie , vol.16 , pp. 140-146
- Bokemeyer, C.¹ Lipp, H.P.² Mayer, F.³ Kanz, L.⁴

50
- 0029964249
- Tradeoffs between quality and quantity of life: Development of the QQ questionnaire for cancer patient attitudes
- (1996) Med Decis Making , vol.16 , pp. 184-192
- Stiggelbout, A.M.¹ De Haes, J.C.² Kiebert, G.M.³ Kievit, J.⁴ Leer, J.W.⁵

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.