Lymphoid environment limits superantigen and antigen-induced T cell proliferation at high precursor frequency

European Journal of Immunology

Volumn 31, Issue 3, 2001, Pages 884-893

  Attinger, Antoine ^a   Robson MacDonald, H ^a   Acha Orbea, Hans ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

Cellular proliferation; Superantigen; T lymphocyte

Indexed keywords

ANTIGEN; FLUORESCENT DYE; PEPTIDE; STAPHYLOCOCCUS ENTEROTOXIN B; SUPERANTIGEN; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN PRESENTING CELL; ARTICLE; CELL CYCLE; CELL DIVISION; CELL LABELING; CELL POPULATION; CONTROLLED STUDY; FREQUENCY ANALYSIS; IN VITRO STUDY; IN VIVO STUDY; LYMPH NODE; LYMPHOCYTE PROLIFERATION; LYMPHOID ORGAN; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROLYMPHOCYTE; RECIPIENT; SPLEEN; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TRANSGENIC MOUSE;

ADOPTIVE TRANSFER; ANIMALS; ANTIGEN-PRESENTING CELLS; ANTIGENS; CELLS, CULTURED; ENTEROTOXINS; FLUORESCEINS; FLUORESCENT DYES; LYMPHOCYTE ACTIVATION; LYMPHOID TISSUE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, TRANSGENIC; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; STEM CELLS; SUCCINIMIDES; SUPERANTIGENS; T-LYMPHOCYTES;

EID: 0035077089     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200103)31:3<884::AID-IMMU884>3.0.CO;2-M     Document Type: Article

References (32)

1. The anatomy of T-cell activation and tolerance
2. Dendritic cells in the T-cell areas of lymphoid organs
3. Chemokines and cell migration in secondary lymphoid organs
4. The formation of immunogenic major histocompatibility complex class II-peptide ligand in lysosomal compartments of dendritic cells is regulated by inflammatory stimuli
5. Dendritic cells and the control of immunity
6. Superantigens: Mechanism of T-cell stimulation and role in immune responses
7. Cutting edge: Apoptosis of superantigen-activated T cells occurs preferentially after a discrete number of cell divisions in vivo
8. Following the fate of individual T cells throughout activation and clonal expansion. Signals from TCR and CD28 differentially regulate the induction and duration of a proliferative response
9. Bacterial superantigens induce rapid and TCR Vβ-selective down-regulation of L-selectin (gp90Mel-14) in vivo
10. Role of the T cell receptor α-chain in superantigen recognition
11. The dendritic cell system and its role in immunogenicity
12. Bacterial superantigens induce T cell unresponsiveness in B cell-deficient mice
13. + T cells in mice tolerant to Staphylococcus aureus enterotoxin B
14. Rapid clearance of the bacterial superantigen staphylococcal enterotoxin B in vivo
15. Staphylococcal enterotoxin B induces an early and transient state of immunosuppression characterized by Vβ-unrestricted T cell unresponsiveness and defective antigen-presenting cell functions
16. Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo
17. Cell division regulates the T cell cytokine repertoire, revealing a mechanism underlying immune class regulation
18. Helper T cell differentiation is controlled by the cell cycle
19. Use of adoptive transfer of T-cell-antigen-receptor-transgenic T cell for the study of T-cell activation in vivo
20. Antigen expressed on tumor cells fails to elicit an immune response, even in the presence of increased numbers of tumor-specific cytotoxic T lymphocyte precursors
21. Viral escape by selection of cytotoxic T cell-resistant virus variants in vivo
22. + cytotoxic T cells to virus clearance or pathologic manifestations of influenza virus infection in a TCR transgenic mouse model
23. Tumor antigens are constitutively presented in the draining lymph nodes
24. B cells turn off virgin but not memory T cells
25. Dendritic cells are potent antigen-presenting cells for microbial superantigens
26. Induction of responsiveness in superantigen-induced anergic T cells. Role of ligand density and costimulatory signals
27. The duration of antigenic stimulation determines the fate of naive and effector T cells
28. Oligoclonal expansion of major histocompatibility complex class I-restricted cytolytic T lymphocytes during a primary immune response in vivo: Direct monitoring by flow cytometry and polymerase chain reaction
29. Counting antigen-specific CD8 T cells: A reevaluation of bystander activation during viral infection
30. Immunopharmacology of the superantigen staphylococcal enterotoxin A in T-cell receptor Vβ3 transgenic mice
31. +TCRIo thymocytes in vivo
32. TCR antagonist peptides induce positive selection