Effect of Bcl-2 on the primordial follicle endowment in the mouse ovary

Biology of Reproduction

Volumn 64, Issue 4, 2001, Pages 1153-1159

  Flaws, J A ^a   Hirshfield, A N ^a   Hewitt, J A ^a   Babus, J K ^a   Furth, P A ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Follicle; Gene regulation; Oocyte development; Ovary

Indexed keywords

PROTEIN BCL 2; STEM CELL FACTOR; STEM CELL FACTOR RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; GENE CONTROL; GENE OVEREXPRESSION; HUMAN; MOUSE; NONHUMAN; OOCYTE DEVELOPMENT; OVARY FOLLICLE DEVELOPMENT; PRIORITY JOURNAL; PROTEIN ANALYSIS; REGULATORY MECHANISM; TRANSGENE; TRANSGENIC MOUSE;

ANIMALIA; MUS MUSCULUS;

EID: 0035076648     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod64.4.1153     Document Type: Article

References (45)

1. Development of follicles in the mammalian ovary
2. Migration of gonocytes into the mammalian gonad and their differentiation
3. Proliferation and migration of primordial germ cells during compensatory growth in mouse embryos
4. Emergence and migration of mouse primordial germ cells
5. Migratory and post migratory mouse primordial germ cells behave differently in culture
6. Ablation of bcl-2 gene expression decreases the numbers of oocytes and primordial follicles established in the post-natal female mouse gonad
7. A quantitative and cytological study of oogonia and oocytes in the foetal and neonatal rat
8. Changes in proto-oncogene expression correlated with general and sex-specific differentiation in murine primordial germ cells
9. Patterns of RNA synthesis in early meiotic prophase oocytes from fetal mouse ovaries
10. Oogenesis in the mouse: A study of the meiotic prophase
11. Stem cell factor and leukemia inhibitory factor promote primordial germ cell survival by suppressing programmed cell death (apoptosis)
12. The expression of c-kit protein during oogenesis and early embryonic development
13. Expression of c-kit ligand messenger ribonucleic acids in human ovaries and regulation of their steady state levels by gonadotropins in cultured granulosa-luteal cells
14. Dynamic changes in ovarian c-kit and steel expression during the estrous reproductive cycle
15. Expression of c-kit messenger ribonucleic acid in human oocyte and presence of soluble c-kit in follicular fluid
16. Embryonic RNA expression patterns of the c-kit receptor and its cognate ligand suggest multiple functional roles in mouse development
17. The expression pattern of the c-kit ligand in gonads of mice supports a role for the c-kit receptor in oocyte growth and in proliferation of spermatogonia
18. Developmental expression of c-kit, a proto-oncogene encoded by the W locus
19. Expression of c-kit encoded at the W locus of mice in developing embryonic germ cells and presumptive melanoblasts
20. Direct actions of kit-ligand on theca cell growth and differentiation during follicle development
21. The murine steel panda mutation affects kit ligand expression and growth of early ovarian follicles
22. t mice
23. A study of the primordial germ cells during their migratory phase in steel mutant mice
24. Requirement for mast cell growth factor for primordial germ cell survival in culture
25. Effects of the steel gene product on mouse primordial germ cells in culture
26. L and Bcl-2, displaces bax and promotes cell death
27. Programmed cell death and the control of cell survival: Lessons from the nervous system
28. Bcl-2 initiates a new category of oncogenes: Regulators of cell death
29. Double identity for proteins of the bcl-2 family
30. Expression and function of a proapoptotic Bcl-2 family member Bcl-XL/Bcl-2-associated death promoter (BAD) in rat ovary
31. Differential expression of apoptosis associated genes bax and bcl-2 in ovarian cancer
32. Apoptosis regulator Bcl-w is essential for spermatogenesis but appears otherwise redundant
33. Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
34. Bax and bcl-xs are induced at the onset of mammary gland involution
35. Targeted overexpression of Bcl-2 in ovaries of transgenic mice leads to decreased follicle apoptosis, enhanced folliculogenesis, and increased germ cell tumorigenesis
36. long messenger ribonucleic acid levels
37. Targeted expression of bcl-2 in mouse oocytes inhibits ovarian follicle atresia and prevents spontaneous and chemotherapy-induced oocyte apoptosis in vitro
38. Regulation of oocyte growth in the mouse ovary
39. The development of oocytes and ovarian follicles of mammals
40. A theory of follicle selection
41. Relationship between the supply of primordial follicles and the onset of follicular growth in rats
42. Accelerated disappearance of ovarian follicles in mid-life: Implications for forecasting menopause
43. A model conforming the decline in follicle numbers to the age of menopause in women
44. Follicular depletion during the menopausal transition: Evidence for accelerated loss and ultimate exhaustion
45. Imminent oocyte exhaustion and reduced follicular recruitment mark the transition to acyclicity in aging C57BL/6J mice