Photomechanical transdermal delivery of insulin in vivo

Lasers in Surgery and Medicine

Volumn 28, Issue 3, 2001, Pages 282-285

  Lee, Shun ^a   McAuliffe, Daniel J ^a   Mulholland, Stephen E ^a   Doukas, Apostolos G ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Protein delivery; Shock waves; Stress waves; Transcutaneous drug delivery

Indexed keywords

INSULIN; STREPTOZOCIN;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG PENETRATION; GLUCOSE BLOOD LEVEL; INSULIN TREATMENT; LASER; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SHOCK WAVE; SKIN PERMEABILITY; STRATUM CORNEUM; STREPTOZOCIN DIABETES;

ADMINISTRATION, CUTANEOUS; ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; DRUG DELIVERY SYSTEMS; INSULIN; LASERS; MALE; RATS; RATS, SPRAGUE-DAWLEY; REFERENCE VALUES; SENSITIVITY AND SPECIFICITY; SKIN ABSORPTION; STREPTOZOCIN;

EID: 0035072546     PISSN: 01968092     EISSN: None     Source Type: Journal    
DOI: 10.1002/lsm.1052     Document Type: Article

References (11)

1. Physical characteristics and biological effects of laser-induced stress waves
2. Laser-generated stress waves and their effects on the cell membrane
3. Photomechanical transcutaneous delivery of macromolecules
4. Topical drug delivery in humans with a single photomechanical wave
5. Transdermal delivery of insulin to alloxan-diabetic rabbits by ultrasound exposure
6. Ultrasound-mediated transdermal protein delivery
7. Physical study of laser-produced plasma in confined geometry
8. Cutaneous microdialysis methodology and validation
9. Transcutaneous molecular delivery in vivo with a single mechanical pulse
10. Ultrastructural basis of permeabilization of human skin by photomechanical waves
11. Morphologic basis for a pore-pathway in mammalian stratum corneum