Functional analysis of the Xenopus frizzled 7 protein domains using chimeric receptors

International Journal of Developmental Biology

Volumn 45, Issue 1, 2001, Pages 259-264

  Swain, R K ^a   Medina, A ^a   Steinbeisser, H ^a  

^a MAX PLANCK INSTITUTE FOR DEVELOPMENTAL BIOLOGY   (Germany)

Author keywords

Chimeric receptor; Hfz5; Wnt signaling; Xenopus; Xfz7

Indexed keywords

CATENIN; CHIMERIC PROTEIN; RECEPTOR;

ARTICLE; CARBOXY TERMINAL SEQUENCE; EMBRYO; GENE ACTIVATION; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN INTERACTION; RECEPTOR BINDING; SIGNAL TRANSDUCTION; XENOPUS;

ANIMALS; BASE SEQUENCE; DNA PRIMERS; FRIZZLED RECEPTORS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; PROTEIN STRUCTURE, TERTIARY; PROTEINS; PROTO-ONCOGENE PROTEINS; RECEPTORS, CELL SURFACE; RECEPTORS, G-PROTEIN-COUPLED; RECOMBINANT FUSION PROTEINS; RNA, MESSENGER; SIGNAL TRANSDUCTION; WNT PROTEINS; XENOPUS; XENOPUS PROTEINS; ZEBRAFISH PROTEINS;

VERTEBRATA;

EID: 0035069658     PISSN: 02146282     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Betacatenin is a target for the ubiquitin-proteasome pathway
2. Frizzled proteins constitute a novel family of G protein-coupled receptors, most closely related to the secretin family
3. Frizzled and Dfrizzled-2 function as redundant receptors for Wingless during Drosophila embryonic development
4. A beta-catenin/XTcf-3 complex binds to the siamois promoter to regulate dorsal axis specification in Xenopus
5. Pangolin encodes a Lef-1 homologue that acts downstream of Armadillo to transduce the Wingless signal in Drosophila
6. Wnt signaling: A common theme in animal development
7. Xwnt-8b: A maternally expressed Xenopus Wnt gene with a potential role in establishing the dorsoventral axis
8. Frizzled-8 is expressed in the Spemann organizer and plays a role in early morphogenesis
9. Identification of distinct classes and functional domains of Wnts through expression of wild-type and chimeric proteins in Xenopus embryos
10. Keeping a close eye on Wnt-1/wg signaling in Xenopus
11. A member of the Frizzled protein family mediating axis induction by Wnt-5A
12. A role for Xenopus Frizzled 8 in dorsal development
13. Axis determination by inhibition of Wnt signaling in Xenopus
14. Xwnt-2b is a novel axis-inducing Xenopus Wnt, which is expressed in embryonic brain
15. The Xenopus homeobox gene twin mediates Wnt induction of goosecoid in establishment of Spemann's organizer
16. LEF-1/TCF proteins mediate wnt-inducible transcription from the Xenopus nodal-related 3 promoter
17. Ectopic expression of the proto-oncogene int-1 in Xenopus embryos leads to duplication of the embryonic axis
18. Xenopus frizzled 7 can act in canonical and non-canonical wnt signaling pathways: Implications on early patterning and morphogenesis
19. 2+ pathways
20. Xwnt-5A: A maternal Wnt that affects morphogenetic movements after overexpression in embryos of Xenopus laevis
21. From cortical rotation to organizer gene expression: Toward a molecular explanation of axis specification in Xenopus
22. Mesodermal patterning by a gradient of the vertebrate homeobox gene goosecoid
23. Antisense wnt-5a mimics wnt-1-mediated C57MG mammary epithelial cell transformation
24. Injected Wnt RNA induces a complete body axis in Xenopus embryos
25. Overlapping expression of Xwnt-3A and Xwnt-1 in neural tissue of Xenopus laevis embryos
26. A frizzled homolog functions in a vertebrate Wnt signaling pathway