Prothrombin Scranton: Substitution of an amino acid residue involved in the binding of Na+ (LYS-556 to THR) leads to dysprothrombinemia

Thrombosis and Haemostasis

Volumn 85, Issue 4, 2001, Pages 651-654

  Sun, W Y ^a   Smirnow, D ^a   Jenkins, M L ^a   Degen, S J F ^a  

^a CINCINNATI CHILDREN S HOSPITAL RESEARCH FOUNDATION   (United States)

Author keywords

Abnormal prothrombin; Dysprothrombinemia; Na+ binding; Prothrombin; SSCP heteroduplex analysis

Indexed keywords

AMINO ACID; ANTIGEN; DNA; PROTHROMBIN; SODIUM;

ADOLESCENT; AMINO ACID SUBSTITUTION; ARTICLE; BINDING KINETICS; BLEEDING; BLOOD CLOTTING; CLINICAL ARTICLE; CONTROLLED STUDY; DYSPROTHROMBINEMIA; ENZYME ACTIVITY; FAMILIAL INCIDENCE; GENE MUTATION; GENE STRUCTURE; GENETIC ANALYSIS; GENOME; HETERODUPLEX ANALYSIS; HUMAN; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; RESIDUE ANALYSIS; SEQUENCE ANALYSIS; SINGLE STRAND CONFORMATION POLYMORPHISM;

EID: 0035067691     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0037-1615648     Document Type: Article

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