The BMP antagonists cerberus-like and noggin do not interact during mouse forebrain development

International Journal of Developmental Biology

Volumn 45, Issue 2, 2001, Pages 441-444

  Borges, A C ^a   Marques, S ^a   Belo, J A ^a  

^a INSTITUTO GULBENKIAN DE CIÊNCIA   (Portugal)

Author keywords

BMP 4; Head induction; Mouse cerberus like; Noggin

Indexed keywords

BINDING PROTEIN; BONE MORPHOGENETIC PROTEIN BINDING PROTEIN; MUTANT PROTEIN; NOGGIN; UNCLASSIFIED DRUG;

ARTICLE; BRAIN DEVELOPMENT; EMBRYO; EMBRYO DEVELOPMENT; FOREBRAIN; GENE MUTATION; GENOTYPE; IN SITU HYBRIDIZATION; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN FAMILY;

ANIMALS; ANIMALS, NEWBORN; BONE MORPHOGENETIC PROTEINS; CARRIER PROTEINS; GENETIC COMPLEMENTATION TEST; GENOTYPE; GLYCOPROTEINS; IN SITU HYBRIDIZATION; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, MUTANT STRAINS; MUTATION; POLYMERASE CHAIN REACTION; PROSENCEPHALON; PROTEINS;

CERBERUS;

EID: 0035064453     PISSN: 02146282     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. The organizer factors Chordin and Noggin are required for mouse forebrain development
2. Cerberus-like is a secreted factor with neuralizing activity expressed in the anterior primitive endoderm of the mouse gastrula
3. The prechordal midline of the chondrocranium is defective in Goosecoid-1 mouse mutants
4. Cerberus-like is a secreted BMP and Nodal antagonist not essential for mouse development
5. Murine Cerberus homologue mCer-1: A candidate anterior patterning molecule
6. Cerberus is a head inducing secreted factor expressed in the anterior endoderm of Spamann's organizer
7. Noggin, Cartilage Morphogenesis and joint formation in the mammalian skeleton
8. A common plan for dorsoventral patterning in Bilateria
9. Patterning by genes expressed in the Spemann's organizer
10. Direct binding of follistatin to a complex of bone-morphogenetic protein and its receptor inhibits ventral and epidermal cell fates in early Xenopus embryo
11. En-1 and En-2, two mouse genes with sequence homology to the Drosophila engrailed gene: Expression during embryogenesis
12. Noggin-mediated antagonism of BMP signalling is required for growth and patterning of the neural tube and somite
13. Six-3, a murine homologue of the sine oculis gene, demarcates the most anterior border of the developing neural plate and is expressed during eye development
14. Dorsoventral patterning in Xenopus: Inhibition of ventral signals by direct binding of chordin to BMP-4
15. The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals
16. Expression of the mouse cerberus-related gene, Cerr1, suggests a role in anterior neural induction and somitogenesis
17. The cerberus-related gene, Cerr1, is not essential for mouse head formation
18. Targeted insertion of a lacZ reporter gene into the mouse Cer1 Locus reveals complex and dynamic expression during embryogenesis
19. Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse
20. The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein-4