Chlamydia pneumoniae major outer membrane protein is a surface-exposed antigen that elicits antibodies primarily directed against conformation-dependent determinants

Infection and Immunity

Volumn 69, Issue 5, 2001, Pages 3082-3091

  Wolf, K ^a   Fischer, E ^a   Mead, D ^a   Zhong, G ^a   Peeling, R ^a   Whitmire, B ^a   Caldwell, H D ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ANTIGEN; MONOCLONAL ANTIBODY; OUTER MEMBRANE PROTEIN;

ANTIBODY RESPONSE; ANTIGEN ANTIBODY REACTION; ANTIGEN RECOGNITION; ARTICLE; CHLAMYDIA TRACHOMATIS; CHLAMYDOPHILA PNEUMONIAE; HELA CELL; HUMAN; HUMAN CELL; IMMUNOGENICITY; IMMUNOPRECIPITATION; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS;

AMINO ACID SEQUENCE; ANTIBODIES, BACTERIAL; ANTIBODIES, MONOCLONAL; BACTERIAL OUTER MEMBRANE PROTEINS; CHLAMYDOPHILA PNEUMONIAE; EPITOPES; HELA CELLS; HUMANS; MOLECULAR SEQUENCE DATA; PRECIPITIN TESTS; PROTEIN CONFORMATION;

EID: 0035063966     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.69.5.3082-3091.2001     Document Type: Article

References (42)

1. Reactivity of monoclonal antibodies to Rickettsia rickettsii with spotted fever and typhus group rickettsiae
2. Mapping antigenic domains expressed by Chlamydia trachomatis major outer membrane protein genes
3. Antigenic variation among strains of Chlamydia pneumoniae
4. Molecular diagnosis of Chlamydia pneumoniae infection
5. Immunoperoxidase methods for the localization of antigens in cultured cells and tissue sections by electron microscopy
6. Purification and partial characterization of the major outer membrane protein of Chlamydia trachomatis
7. Neutralization of Chlamydia trachomatis infectivity with antibodies to the major outer membrane protein
8. Antigenic analysis of the major outer membrane protein of Chlamydia spp.
9. Chlamydia pneumoniae and cardiovascular disease
10. Structural and antigenic analysis of Chlamydia pneumoniae
11. Serological response to Chlamydia pneumoniae infection
12. Unique ultrastructure in the elementary body of Chlamydia sp. strain TWAR
13. Molecular biology of Chlamydia pneumoniae surface proteins and their role in immunopathogenicity
14. Analysis of the humoral immune response to Chlamydia pneumoniae by immunoblotting and immunoprecipitation
15. Infections caused by Chlamydia pneumoniae strain TWAR
16. Characterization of Chlamydia pneumoniae species-specific proteins immunodominant in humans
17. Antigenic and molecular analyses of different Chlamydia pneumoniae strains
18. HIV-1 rev nuclear export signal binding peptides isolated by phage display
19. Antigenic characterization of Chlamydia pneumoniae isolated in Hiroshima, Japan
20. Identification of two novel genes encoding 97- to 99-kilodalton outer membrane proteins of Chlamydia pneumoniae
21. Chlamydia pneumoniae
22. Factors affecting viability and growth in HeLa 229 cells of Chlamydia sp. strain TWAR
23. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
24. Recognition by human sera and immunogenicity of HBsAg mimotopes selected from an M13 phage display library
25. Disulfide-linked oligomers of the major outer membrane protein of chlamydiae
26. Identification of yeast proteins from two-dimensional gels: Working out spot cross-contamination
27. Protective role of magnesium in the neutralization by antibodies of Chlamydia trachomatis infectivity
28. Further characterization of Chlamydia pneumoniae specific monoclonal antibodies
29. Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae AR39
30. Sphingolipids and glycoproteins are differentially trafficked to the Chlamydia trachomatis inclusion
31. Genome sequence of an obligate intracellular pathogen of humans: Chlamydia trachomatis
32. Diversity of Chlamydia trachomatis major outer membrane protein genes
33. Comparison of Chlamydia pneumoniae isolates by Western blot (immunoblot) analysis and DNA sequencing of the omp 2 gene
34. The microimmunofluorescence test for Chlamydia pneumoniae infection: Technique and interpretation
35. Ultrastructural analysis of developmental events in Chlamydia pneumoniae-infected cells
36. Monoclonal antibodies define genus-specific, species-specific, and cross-reactive epitopes of the chlamydial 60-kilodalton heat shock protein (hsp60): Specific immunodetection and purification of chlamydial hsp60
37. Nucleotide and deduced amino acid sequences for the four variable domains of the major outer membrane proteins of the 15 Chlamydia trachomatis serovars
38. Cloning and sequence analysis of the major outer membrane protein genes of two Chlamydia psittaci strains
39. Protective monoclonal antibodies recognize epitopes located on the major outer membrane protein of Chlamydia trachomatis
40. Protective monoclonal antibodies to Chlamydia trachomatis serovar- and serogroup-specific major outer membrane protein determinants
41. The low-molecular-mass, cysteine-rich outer membrane protein of Chlamydia trachomatis possesses both biovar- and species-specific epitopes
42. Conformational mimicry of a chlamydial neutralization epitope on filamentous phage