Protection and injury: The differing roles of complement in the development of glomerular injury

European Journal of Immunology

Volumn 31, Issue 4, 2001, Pages 1255-1260

  Sheerin, Neil Stephen ^a   Springall, Tabitha ^a   Abe, Katsushige ^a   Sacks, Steven Howard ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Anti GBM disease; Complement; Glomerulonephritis; Immune complex

Indexed keywords

COMPLEMENT; COMPLEMENT COMPONENT C3; GLOMERULUS BASEMENT MEMBRANE ANTIBODY;

ACUTE DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN BINDING; ARTICLE; AUTOIMMUNE DISEASE; BINDING AFFINITY; COMPLEMENT ACTIVATION; COMPLEMENT DEFICIENCY; CONTROLLED STUDY; DISEASE MODEL; DISEASE PREDISPOSITION; DISEASE SEVERITY; FEMALE; GLOMERULONEPHRITIS; GLOMERULUS BASEMENT MEMBRANE; IMMUNE COMPLEX DEPOSITION; IMMUNE COMPLEX DISEASE; IMMUNE RESPONSE; INFLAMMATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEINURIA; UREMIA;

ANIMALS; ANTI-GLOMERULAR BASEMENT MEMBRANE DISEASE; ANTIBODIES; ANTIGEN-ANTIBODY COMPLEX; APOPTOSIS; BASEMENT MEMBRANE; COMPLEMENT C3; DISEASE MODELS, ANIMAL; GENE DELETION; IMMUNOGLOBULIN G; KIDNEY GLOMERULUS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROTEINURIA; SERUM ALBUMIN; UREMIA;

EID: 0035063240     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200104)31:4<1255::AID-IMMU1255>3.0.CO;2-W     Document Type: Article

References (22)

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8. Evidence for delayed-type hypersensitivity mechanisms in glomerular crescent formation
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10. Antibody independent crescentic glomerulonephritis in mu chain deficient mice
11. Transgenic mice overexpressing the complement inhibitor crry as a soluble protein are protected from antibody-induced glomerular injury
12. Quantitation of exogenous and endogenous components of glomerular immune deposits
13. Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies
14. Acute nephrotoxic serum nephritis in complement knockout mice: Relative role of the classical and alternate pathways in neutrophil recruitment and proteinuria
15. Impaired humoral immune response in complement C3-deficient guinea pigs: Absence of secondary antibody response
16. Role of complement in the induction of the allergic response
17. Delayed removal of renal bound antigen in decomplemented rabbits with acute serum sickness
18. Chronic serum sickness glomerulonephritis: Removal of glomerular antigen and electrondense deposits is largely dependent on plasma complement
19. Heterologous nephrotoxic nephritis: Delayed resolution of inflammation in C1q deficient mice
20. Studies of group B streptococcal infection in mice deficient in complement component C3 or C4 demonstrate an essential role for complement in both innate and acquired immunity
21. Anti-GBM nephritis in the mouse: Severe proteinuria in the heterologous phase
22. Role of complement in acute tubulointerstitial injury of rats with aminonucleoside nephrosis