Enhanced expression of cyclin E and cyclin A in human hepatocellular carcinomas

Anticancer Research

Volumn 21, Issue 1 B, 2001, Pages 657-662

  Ohashi, R ^a   Gao, C ^a   Miyazaki, M ^a   Hamazaki, K ^a   Tsuji, T ^a   Inoue, Y ^a   Uemura, T ^a   Hirai, R ^a   Shimizu, N ^a   Namba, M ^a  

^a OKAYAMA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

Cell growth; Cyclin E; Hepatoma

Indexed keywords

CYCLIN A; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLIN E; KI 67 ANTIGEN; PROTEIN P53; RETINOBLASTOMA PROTEIN;

ADULT; AGED; ARTICLE; CELL CYCLE; CELL GROWTH; CLINICAL ARTICLE; FEMALE; HISTOLOGY; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; LIVER CELL CARCINOMA; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR GROWTH; TUMOR SUPPRESSOR GENE;

AGED; AGED, 80 AND OVER; BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; CELL CYCLE PROTEINS; CYCLIN A; CYCLIN E; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLINS; FEMALE; G1 PHASE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, P53; HUMANS; KI-67 ANTIGEN; LIVER NEOPLASMS; MALE; MICROTUBULE-ASSOCIATED PROTEINS; MIDDLE AGED; NEOPLASM PROTEINS; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RETINOBLASTOMA PROTEIN; TUMOR SUPPRESSOR PROTEINS;

EID: 0035061942     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Cancer cell cycle
2. The retinoblastoma protein pathway in cell cycle control and cancer
3. Cyclin and cancer II: Cyclin D and CDK inhibitors come of age
4. The tumour suppressor protein p16
5. Expression of cell-cycle regulators p27 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients
6. Deregulation of cyclin E and D1 in breast cancer is associated with inactivation of the retinoblastoma protein
7. Aberrations of tumour suppressor p53 and retinoblastoma gene in human hepatocellular carcinomas
8. Genetic changes and histological grades in human hepatocellular carcinomas
9. Allelotype analysis of hepatocellular carcinoma
10. Cell cycle regulators and human hepatocarcinogenesis
11. Cyclin E overexpression of human hepatic tumors with p21
12. Screening for heterozygous p53 mutations using a functional assay in yeast
13. Yeast functional assay of the p53 gene status in 11 cell lines and 26 surgical specimens of human hepatocellular carcinoma
14. Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by monoclonal antibody Ki-67
15. Natural history of small untreated hepatocellular carcinomas in cirrhosis
16. Cyclin E in human cancers
17. Deregulated cyclin E induces chromosome instability
18. Over-expression of cyclin A but not skp2 correlates with the tumour relapse of human hepatocellular carcinoma
19. Decreased level of the cell-cycle inhibitor p27 protein: Prognostic implication in primary breast cancer
20. Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas
21. Increased levels of p21WAF1 in human brain tumors
22. p21 RNA protein expression in non-small cell lung carcinoma: Evidence of p53-independent expression and association with tumoral differentiation
23. Altered WAF1 genes do not play a role in abnormal cell cycle regulation in breast cancers lacking p53 mutations
24. Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation