Global improvement in left ventricular performance observed with cardiac contractility modulation is the result of changes in regional contractility

Heart Failure Reviews

Volumn 6, Issue 1, 2001, Pages 35-44

  Callans, David J ^a   Fuchs, Shmuel ^b   Mika, Yuval ^c   Shemer, Itzhak ^c   Aviv, Ricardo ^c   Haddad, Walid ^c   Darvish, Nissim ^c   Ben Haim, Shlomo A ^c   Kornowski, Ran ^b  

^a HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

^b Washington Hospital Center   (United States)

^c Impulse Dynamics ^*  (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

AMRINONE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CYCLIC AMP; DIGITALIS; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DOBUTAMINE; ENOXIMONE; IBOPAMINE; INOTROPIC AGENT; MILRINONE; PIPERANOMETOZINE; SPIRONOLACTONE; XAMOTEROL;

CONFERENCE PAPER; CONGESTIVE HEART FAILURE; CONTROLLED STUDY; CYCLIC AMP BLOOD LEVEL; DEFIBRILLATOR; DISEASE CLASSIFICATION; DISEASE SEVERITY; DRUG EFFECT; DRUG FATALITY; ELECTRODE; ELECTROSTIMULATION THERAPY; EXPERIMENT; FUNCTIONAL ASSESSMENT; HEART LEFT VENTRICLE DP-DT; HEART MUSCLE CONTRACTILE FORCE; HEART MUSCLE CONTRACTILITY; HEART RIGHT VENTRICLE PERFORMANCE; HEART VENTRICLE PACING; HUMAN; MODULATION; NONHUMAN; SPATIAL SUMMATION; STRAIN GAUGE TRANSDUCER; SYSTOLE; TARGET ORGAN; TIME; TREATMENT OUTCOME;

ANIMALS; DOGS; ELECTRIC STIMULATION THERAPY; HEART FAILURE, CONGESTIVE; MYOCARDIAL CONTRACTION; SWINE; VENTRICULAR FUNCTION, LEFT;

EID: 0035061632     PISSN: 13824147     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1009803224027     Document Type: Conference Paper

References (32)

1. Predictors of total mortality and sudden death in mild to moderate heart failure
2. The clinical course of idiopathic dilated cardiomyopathy
3. Survival after the onset of congestive heart failure in Framingham Heart Study subjects
4. Effects of enalapril on mortality in severe congestive heart failure: Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS). The CONSENSUS Trial Study Group
5. Effect of enalapril on survival in patients with reduced left ventricular ejection fraction and congestive heart failure. The SOLVD Investigators
6. Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. The SAVE Investigators
7. The effect of carvedilol on morbidity and mortality in patients with chronic heart failure. U.S. Carvedilol Heart Failure Study Group
8. Randomized, placebo-controlled trial of carvedilol in patients with congestive heart failure due to ischemic heart disease
9. Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervetion Trial in Congestive Heart Failure (MERIT-HF)
10. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators
11. Extracorporeal life support to left ventricular assist device bridge to heart transplant: A strategy to optimize survival and resource utilization
12. The effect of digoxin on mortality and morbidity in patients with heart failure. The Digitalis Investigation Group
13. Multicenter trial of oral enoximone in patients with moderate to moderately severe congestive heart failure
14. Effect of oral milrinone on mortality in severe chronic heart failure
15. Ambulatory intermittent 6-month low-dose dobutamine infusion in severe heart failure: DICE multicenter trial
16. Randomized study of the effect of ibopamine on survival in patients with advanced severe heart failure
17. Multisite pacing for end-stage heart failure: Early experience
18. Evaluation of different ventricular pacing sites in patients with severe heart failure: Results of an acute hemodynamic study
19. Acute hemodynamic effects of biventricular DDD pacing in patients with end-stage heart failure
20. Improved left ventricular mechanics from acute VDD pacing in patients with dilated cardiomyopathy and ventricular conduction delay
21. Effect of pacing chamber and atrioventricular delay on acute systolic function of paced patients with congestive heart failure
22. Electrocardiographic predictive factors of long term clinical improvement with multisite biventricular pacing in advanced heart failure
23. Predictors of systolic augmentation from left ventricular preexcitation in patients with dilated cardiomyopathy and intraventricular conduction delay
24. Delivery of non-excitatory contractility modulation electrical signals improve left ventricular performance in dogs with heart failure
25. Myocardial contractility modulation using a non-excitatory electrical signal
26. Potential gain in left ventricular contractility with non-stimulatory signals on top of biventricular pacing
27. Comparative increase in ventricular contractile force produced by several cardiac glycosides
28. Mapping of regional myocardial strain and work during ventricular pacing experimental study using magnetic resonance tagging
29. Electromechanical characterization of myocardial hibernation in a pig model
30. First clinical experience demonstrating improvement of hemodynamic parameters in heart failure patients through the application of non-excitatory electrical signals