Management of acute variceal haemorrhage

European Journal of Gastroenterology and Hepatology

Volumn 13, Issue 4, 2001, Pages 335-342

  Vlavianos, Pakis ^a   Westaby, David ^a  

^a CHELSEA AND WESTMINSTER HOSPITAL   (United Kingdom)

Author keywords

Cirrhosis; Endoscopic variceal banding ligation; Glypressin; Injection sclerotherapy; Keywords; Nitroglycerin; Ocreotide; Portal hypertension; Portocaval shunt; Somatostatin; Transjugular intrahepatic portosystemic stent shunt; Variceal bleeding; Vasopressin

Indexed keywords

OCTREOTIDE; SOMATOSTATIN; TERLIPRESSIN; VASOPRESSIN;

DISEASE COURSE; ENDOSCOPY; ESOPHAGUS VARICES; ESOPHAGUS VARICES BLEEDING; HUMAN; LIVER CIRRHOSIS; PORTAL HYPERTENSION; PORTOCAVAL SHUNT; PORTOSYSTEMIC ANASTOMOSIS; PRIORITY JOURNAL; RESUSCITATION; REVIEW;

ENDOSCOPY; ESOPHAGEAL AND GASTRIC VARICES; GASTROINTESTINAL HEMORRHAGE; HORMONES; HUMANS; LYSINE VASOPRESSIN; PORTASYSTEMIC SHUNT, TRANSJUGULAR INTRAHEPATIC; RESUSCITATION; SCLEROTHERAPY; SOMATOSTATIN; VASOCONSTRICTOR AGENTS; VASOPRESSINS;

EID: 0035054156     PISSN: 0954691X     EISSN: 14735687     Source Type: Journal    
DOI: 10.1097/00042737-200104000-00006     Document Type: Review

References (118)

1. D'Amico G, Pasta L, Vizzini GB, Politi F, Traina M, Caltagirone M. et al. Natural history of cirrhosis [Abstract]. J Hepatol 1990; 13: S22. S22.
2. Baker LA, Smith C, Lieberman G. The natural history of oesophageal varices. Am J Med 1959; 26: 228 -237.
3. Pagliaro L, D'Amico G, Sorensen TIA, Lebrec D, Burroughs AK, Morabito A. et al. Prevention of first bleeding in cirrhosis. A meta-analysis of randomized clinical trials of non-surgical treatment. Ann Int Med 1992; 117: 59 -70.
4. D'Amico G, Morabito A, Pagliaro L, Marubini E, and the Liver Study Group of V Cervello Hospital. Survival and prognostic indicators in compensated and decompensated cirrhosis. Dig Dis Sci 1986; 31: 468 -475.
5. D'Amico G, Pagliaro L, Bosch J. The treatment of portal hypertension: a meta-analytic review. Hepatology 1995; 22: 332 -353.
6. Pagliaro L, de Francis R. Where were we? A summary of the issues where consensus was reached at Baveno I. In:Portal Hypertension II. de Francis R (editor). Oxford: Blackwell; 1996. pp. 1 -9.
7. Kravetz D, Bosch J, Arderiu M, Pizcueta MP, Rodes J. Hemodynamic effects of blood volume restitution following a hemorrhage in rats with portal hypertension due to cirrhosis of the liver: influence of the extent of portal-systemic shunting. Hepatology 1989; 9: 808 -814.
8. Vlavianos P, MacMathuna P, Williams R, Westaby D. Splanchnic and systemic haemodynamic response to volume changes in patients with cirrhosis and portal hypertension. Clin Sci 1999; 96: 475 -481.
9. Levacher S, Letoumelin P, Pateron D, Blaise M, Lapandry C, Pourriat J-L. Early administration of terlipressin plus glyceryl trinitrate to control active upper gastrointestinal bleeding in cirrhotic patients. Lancet 1995; 346: 865 -868.
10. Burroughs AK, McCormick A, Hughes MD, Sprengers D, D'Heygere F, McIntyre N. Randomized, double-blind, placebo controlled trial of somatostatin for variceal bleeding. Emergency control and prevention of early variceal rebleeding. Gastroenterology 1990; 99: 1388 -1395.
11. Avgerinos A, Nevens F, Raptis S, Fevery J, and the European Acute Bleeding Oesophageal Variceal Episodes (ABOVE) Study Group. Early administration of somatostatin and efficacy of sclerotherapy in acute oesophageal variceal bleeds: the ABOVE randomized trial. Lancet 1997; 350: 1495 -1499.
12. Reichen J. Liver function and pharmacological considerations in pathogenesis and treatment of portal hypertension. Hepatology 1990; 11: 1066 -1078.
13. Merigan TC, Plotkin GR, Davidson CS. Effect of intravenously administered posterior pituitary extract on hemorrhage from bleeding esophageal varices. N Engl J Med 1962; 266: 134 -135.
14. Conn HO, Ramsby GR, Storer EH, Mutchnick MG, Joshi PH, Phillips MM. et al. Intra-arterial vasopressin in the treatment of upper, gastrointestinal hemorrhage: a prospective controlled clinical trial. Gastroenterology 1975; 68: 211 -221.
15. Mallory A, Schaefer JW, Cohen JR, Holt AS, Norton LW. Selective intra-arterial vasopressin infusion for upper gastrointestinal tract hemorrhage. A controlled clinical trial. Arch Surg 1980; 115: 30 -32.
16. Fogel RM, Knauer MC, Andres LL, Mahal AS, Stein D, Kemeny JM. et al. Continuous intravenous vasopressin in active upper gastrointestinal bleeding. A placebo-controlled trial. Ann Intern Med 1982; 96: 565 -569.
17. Johnson WC, Widrich WC, Ansell JE, Robbins AH, Nabseth DC. Control of bleeding varices by vasopressin: a prospective randomized study. Ann Surg 1977; 186: 369 -376.
18. Clanet J, Tournet R, Fourtanier G, Joncquiert F, Pascal JP. Traitment pour la pitressin des hemorrhagies pour rupture de varices oesophagiennes chez le cirrhotique. Etude controllee. Acta Gastroenterol Bel 1978; 41: 539 -543.
19. Chojkier M, Groszmann RJ, Atterbury CE, Bar-Meir S, Blei AT, Frankel J. et al. A controlled comparison of continuous intra-arterial and intravenous infusion of vasopressin in hemorrhage from esophageal varices. Gastroenterology 1979; 77: 540 -546.
20. Groszmann RJ, Kravetz D, Bosch J, Glickman M, Bruix J, Bredfelt J. et al. Nitroglycerin improves the hemodynamic response to vasopressin in portal hypertension. Hepatology 1982; 2: 757 -762.
21. Tsai YT, Lay CS, Lai KH, Ng WW, Yeh YS, Wang JY. et al. Controlled trial of vasopressin plus nitroglycerin vs vasopressin alone in the treatment of bleeding esophageal varices. Hepatology 1986; 6: 406 -409.
22. Gimson AES, Westaby D, Hegarty J, Alastair W, Williams R. A randomized trial of vasopressin plus nitroglycerin in the control of acute variceal hemorrhage. Hepatology 1986; 6: 410 -413.
23. Bosch J, Groszman RJ, Garcia-Pagan JC, Teres J, Garcia-Tsao G, Navasa M. et al. Association of transdermal nitroglycerin to vasopressin infusion in the treatment of variceal hemorrhage: a placebo controlled clinical trial. Hepatology 1989; 10: 962 -968.
24. Valla D, Lee SS, Moreau R, Hadengue A, Sayegh R, Lebrec D. Effects de la glypressine sur les circulations splanchnique et systemique des malades atteints de cirrhose. (Effects of Glypressin on splanchnic and systemic circulations in patients with cirrhosis.) Gastroenterol Clin Biol 1985; 9: 877 -880.
25. Nevens F, Steenberg W, Yaps HJF. Assessment of variceal pressure by continuous non-invasive endoscopic registration: a placebo controlled evaluation of the effects of terlipressin and octreotide. Gut 1996; 38: 129 -134.
26. Walker S, Stiehl A, Raedsch R, Kommerell B. Terlipressin in bleeding esophageal varices. A placebo controlled double-blind study. Hepatology 1986; 6: 112 -115.
27. Freeman JG, Cobden MD, Record CO. Placebo-controlled trial of terlipressin (Glypressin) in the management of acute variceal bleeding. J Clin Gastroenterol 1989; 11: 58 -60.
28. Soderlund C, Magnusson I, Torngren S, Lundell L. Terlipressin (triglycyl-lysine vasopressin) controls acute bleeding oesophageal varices. A double-blind, randomized, placebo controlled trial. Scand J Gastroenterol 1990; 25: 622 -630.
29. Freeman JG, Cobden MD, Lishman AH, Record CO. Controlled trial of terlipressin (`Glypressin') versus vasopressin in the early treatment of esophageal varices. Lancet 1982; ii: 66 -68.
30. Desaint B, Florent C, Levy VG. A randomized trial of triglycyl-lysine vasopressin vs lysine vasopressin in active cirrhotic variceal hemorrhage. In:Vasopressin Analogs and Portal Hypertension. Lebrec D, Blei AT (editors). Paris: John Libbey Eurotext; 1987. pp. 155 -157.
31. Chiu WK, Sheen IS, Liaw YF. A controlled study of Glypressin versus vasopressin in the control of bleeding from esophageal varices. J Gastroenterol Hepatol 1990; 5: 549 -553.
32. Lee YF, Tsay YT, Lai KH, Lay CS, Chang TT, Malik U. et al. A randomized controlled study of triclycyl-vasopressin and vasopressin plus nitroglycerin in the control of acute esophageal variceal hemorrhage. Chinese J Gastroenterol 1988; 5: 131 -138.
33. D'Amico G, Traina M, Vizzini G, Tine F, Politi F, Montalbano L. et al. Terlipressin or vasopressin plus transdermal nitroglycerin in a treatment strategy for digestive bleeding in cirrhosis. A randomized clinical trial. J Hepatol 1994; 20: 206 -212.
34. Silvain C, Carpentier S, Sautereau D, Czernichow B, Metreau JM, Forte E. et al. Terlipressin plus transdermal nitroglycerin vs octreotide in the control of acute bleeding from esophageal varices: a multicenter randomized trial. Hepatology 1993; 18: 61 -65.
35. Bosch J, Kravetz D, Rodes J. Effects of somatostatin on hepatic and systemic hemodynamics in patients with cirrhosis of the liver: comparison with vasopressin. Gastroenterology 1981; 80: 518 -525.
36. Cicera I, Feu F, Luca A, Garcia-Pagan JC, Fernandez M, Escorsell A. et al. Effects of bolus injections and continuous infusions of somatostatin and placebo in patients with cirrhosis: a double-blind hemodynamic investigation. Hepatology 1995; 22: 106 -111.
37. Valenzuela JE, Shubert T, Fogel RM, Strong RM, Levine J, Mills LJ. A multicenter, randomized, double-blind trial of somatostatin in the management of acute hemorrhage from esophageal varices. Hepatology 1989; 10: 958 -961.
38. Gotzsche PC, Gjorup I, Bennew H, Brahe N, Becker U, Burcharth F. Somatostatin v placebo in bleeding oesophageal varices: randomised trial and meta-analysis. BMJ 1995; 310: 1495 -1498.
39. Kravetz D, Bosch J, Teres J, Bruix J, Rimola A, Rodes J. Comparison of intravenous somatostatin and vasopressin infusion in treatment of acute variceal hemorrhage. Hepatology 1984; 4: 442 -446.
40. Jenkins SA, Baxter JN, Corbett WA, Devitt P, Ware J, Shields R. A prospective randomized controlled clinical trial comparing somatostatin and vasopressin in controlling acute variceal haemorrhage. BMJ 1985; 290: 275 -278.
41. Bagarani M, Albertini V, Anza M, Barlattani A, Bracci F, Cucchiara G. et al. Effect of somatostatin in controlling bleeding from esophageal varices. Ital J Surg Sci 1987; 17: 21 -26.
42. Cardona C, Vida F, Balanzo J, Cusso X, Farre A, Guarner C. Eficacia terapeutica de la somatostatina versus vasopressina mas nitroglycerina en la hemorrhagia activa por varices esofagogastrica. Gastroenterol Hepatol 1989; 12: 30 -34.
43. Hsia HC, Lee FY, Tsai YT, Lee SD, Lai HK, Lin WJ. et al. Comparison of somatostatin and vasopressin in the control of acute esophageal variceal hemorrhage. A randomized, controlled study. Chinese J Gastroenterol 1990; 7: 71 -78.
44. Saari A, Klvilaasko E, Inberg M, Paakkonen M, Lahtinem J, Hockerstedt K. et al. Comparison of somatostatin and vasopressin in bleeding esophageal varices. Am J Gastroenterol 1990; 85: 804 -807.
45. Rodriguez-Moreno F, Santolaria F, Glez-Reimers E, Gomez JL, Batista N, Conde A. et al. A randomized trial of somatostatin vs vasopressin plus nitroglycerin in the treatment of acute variceal bleeding [Abstract]. J Hepatol 1991; 13: S162. S162.
46. Imperiale TF, Teran JC, MvCullough AJ. A meta-analysis of somatostatin versus vasopressin in the management of acute esophageal variceal hemorrhage. Gastroenterology 1995; 109: 1289 -1294.
47. Walker S, Kreichgauer HP, Bode JC. Terlipressin vs somatostatin in bleeding esophageal varices: a controlled double-blind study. Hepatology 1992; 15: 1023 -1030.
48. Feu F, Ruiz del Arbol LR, Banares R, Planas R, Bosch J, and members of the Variceal Bleeding Study Group. Double-blind randomized controlled trial comparing terlipressin and somatostatin for acute variceal hemorrhage. Gastroenterology 1996; 111: 1291 -1299.
49. Di Febo G, Siringo S, Vacirca M, Santoro P, Merighi S, Mustafa A. et al. Somatostatin and urgent sclerotherapy in active esophageal variceal bleeding [Abstract]. Gastroenterology 1990; 98: A583. A583.
50. Shields R, Jenkins SA, Baxter JN, Kingsnorth AN, Ellenbogen S, Makin CA. et al. A prospective randomized controlled trial comparing the efficacy of somatostatin with injection sclerotherapy in the control of oesophageal varices. J Hepatol 1992; 16: 128 -137.
51. Planas R, Quer JQ, Boix J, Canet J, Armengol M, Cabre E. et al. A prospective randomized trial comparing somatostatin and sclerotherapy in the treatment of acute variceal bleeding. Hepatology 1994; 20: 370 -375.
52. Jenkins SA, Copeland G, Kingsnorth A, Shields R. A prospective randomized controlled trial comparing somatostatin (SMS) and injection sclerotherapy in the control of acute variceal haemorrhage: an interim report [Abstract]. Gut 1992; 33: F221. F221.
53. Burroughs AK. Double blind RCT of 5 day octreotide versus placebo, associated with sclerotherapy trial/failures. Hepatology 1996; 24: 352A. 352A.
54. McKee R. A study of octreotide in oesophageal varices. Digestion 1990; 45 (suppl): 60 -65.
55. Hwang S-J, Lin H-H, Chang C-F, Lee F-Y, Lu C-W, Hsia H-C. et al. A randomized controlled trial comparing octreotide and vasopressin in the control of acute esophageal variceal bleeding. J Hepatol 1992; 16: 320 -325.
56. Jenkins SA, Shields R, Davies M, Elias E, Turnbull AJ, Bassendine MF. et al. A multicenter randomised trial comparing octreotide and injection sclerotherapy in the management and outcome of acute variceal haemorrhage. Gut 1997; 41: 526 -533.
57. Sung JJ, Chung SCS, Lai CW, Chan FKL, Leung JWC, Yung MY. Octreotide infusion or emergency sclerotherapy for variceal haemorrhage. Lancet 1993; 342: 637 -641.
58. Primignani M, Vazzoler MC, Carpinelli L, Nolte A, Hall de Lima MC, Arcidiacono PG. et al. Short term effect of octreotide on intraoesophageal variceal pressure: a double-blind placebo-controlled study. Eur J Gastroenterol Hepatol 1994; 6: 1027 -1031.
59. Besson I, Ingrand P, Person B, Boutroux D, Heresbach D, Bernard P. et al. Sclerotherapy with or without octreotide for acute variceal bleeding. N Engl J Med 1995; 333: 555 -560.
60. Sung JY, Chung SCS, Yung MY, Lai CW, Lau JYW, Lee YT. et al. Prospective randomised study of effect of octreotide on rebleeding from oesophageal varices after endoscopic ligation. Lancet 1995; 346: 1666 -1669.
61. Westaby D. Prevention of recurrent variceal bleeding: endoscopic techniques. Gastrointest Endosc Clin N Am 1992; 2: 121 -136.
62. Soderlund C, Ihre T. Endoscopic sclerotherapy v. conservative management of bleeding esophageal varices. Acta Chir Scand 1986; 151: 449 -456.
63. Larson AW, Cohen H, Zwieiban B, Chapman D, Gourdji M, Korula J. et al. Acute esophageal variceal sclerotherapy. JAMA 1986; 255: 497 -500.
64. El-Zayadi A, El-Din S, Kabil M. Endoscopic sclerotherapy versus medical treatment for bleeding esophageal varices in patients with schistosomal liver disease. Gastrointest Endosc 1988; 34: 314 -317.
65. Westaby D, Hayes P, Gimson AES, Polson R, Williams R. Controlled clinical trial of injection sclerotherapy for active variceal bleeding. Hepatology 1989; 9: 274 -277.
66. Alexandrino P, Alves MM, Fidalgo P, Matos L, Esteves AV, Veloso J. et al. Is sclerotherapy the first choice treatment for active oesophageal variceal bleeding in cirrhotic patients? Final report of a randomized clinical trial. J Hepatol 1990; 11 (suppl): S1. S1.
67. Barsoum MS, Bolous FL, El-Robby AA, Rizk-Allah MA, Ibrahim AS. Tamponade and injection sclerotherapy in the management of bleeding oesophageal varices. Br J Surg 1982; 69: 76 -78.
68. Copenhagen Esophageal Varices Sclerotherapy Project. Sclerotherapy after variceal hemorrhage in cirrhosis. N Engl J Med 1984; 311: 1594 -1600.
69. Paquet KJ, Feusener H. Endoscopic sclerosis and esophageal balloon tamponade in esophageal hemorrhage from esophagogastric varices: a prospective randomized trial. Hepatology 1985; 5: 580 -583.
70. Moreto M, Zaballa M, Bernal A, Ibanez S, Ojembarrena E, Rodriguez A. A randomized trial of tamponade or sclerotherapy as immediate treatment for bleeding esophageal varices. Surg Gynecol Obstet 1988; 167: 331 -334.
71. Westaby D. Emergency and elective endoscopic therapy for variceal haemorrhage. In:Portal Hypertension. Shields R (editor). Baillere's Clin Gastroenterol 1992; 3: 465 -480.
72. Laine L, Cook D. Endoscopic ligation compared with sclerotherapy for treatment of esophageal variceal bleeding. A meta-analysis. Ann Intern Med 1995; 123: 280 -287.
73. Stiegman GV, Goff JS, Michaletz-Onody PA, Korula J, Lieberman D, Saeed ZA. et al. Endoscopic sclerotherapy as compared with endoscopic ligation for bleeding esophageal varices. N Engl J Med 1992; 326: 1527 -1532.
74. Lo GH, Lai KH, Huang JS. Emergency sclerotherapy vs. banding ligation for arresting of actively bleeding esophageal varices [Abstract]. Endoscopy 1996; 28: 1205. 1205.
75. Gimson AES, Ramage JK, Panos MZ, Hayllar K, Harrison PM, Williams R. et al. Randomised trial of variceal banding ligation vs. injection sclerotherapy for bleeding oesophageal varices. Lancet 1993; 342: 391 -394.
76. Laine L, El-Newihi HM, Migikowsky B, Sloane R, Garcia F. Endoscopic ligation compared with sclerotherapy for the treatment of bleeding esophageal varices. Ann Intern Med 1993; 119: 1 -7.
77. Jensen LS, Kovacs TOG, Randall GM, You S, Pelayo E, Jensen ME. et al. Initial results of a randomised prospective study of emergency banding vs. sclerotherapy for bleeding gastric or oesophageal varices [Abstract]. Gastrointest Endosc 1993; 39: 279. 279.
78. Lo GH, Lai KH, Cheng JS, Hwu JH, Channg CF, Chen SM. et al. A prospective, randomised trial of injection sclerotherapy vs. banding ligation in the management of bleeding oesophageal varices. Hepatology 1995; 22: 466 -471.
79. Hou MC, Lin HC, Kou BIT, Chen CH, Lee FY, Lee SD. Comparison of endoscopic variceal injection sclerotherapy and ligation for the treatment of esophageal hemorrhage: a prospective randomized trial. Hepatology 1995; 21: 1517 -1522.
80. Fakhry S, Omer M, Nouh A, Al-Ghannam M, Serry M, Attia M. et al. Endoscopic sclerotherapy vs. endoscopic variceal ligation in the management of bleeding esophageal varices: a preliminary report of a prospective randomized study [Abstract]. Hepatology 1995; 22: 251. 251.
81. Sarin SK, Goyal A, Jain A, Guptan RC, Murthy MS. Randomized controlled trial of endoscopic sclerotherapy vs ligation for bleeding oesophageal varices: influence on gastropathy, gastric varices and recurrences [Abstract]. Gastroenterology 1995; 108: A629. A629.
82. De la Pena J, Rivero M, Sanchez E, Fabrega E, Crespo J, Pons-Romero F. Variceal ligation compared with endoscopic sclerotherapy for variceal hemorrhage: prospective randomized trial. Gastrointest Endosc 1999; 49: 417 -423.
83. Veltzke W, Adler A, Hintze RE. Role of endoscopic ligation in active variceal bleeding under emergency conditions [Abstract]. Endoscopy 1996; 28: 1204. 1204.
84. Williams SG, Peters RA, Westaby D. Thrombin - an effective treatment for fundal gastric varices? Gut 1994; 35: 1287 -1289.
85. Fiaccadori F, Pedretti G, Biraghi M, Arcidiacono R. Terlipressin and endoscopic sclerotherapy control variceal bleeding and prevent early rebleeding in cirrhotic patients. Curr Ther Res 1993; 54: 519 -527.
86. Brunati S, Ceriani R, Curioni R, Brunelli L, Repaci G, Morini L. Sclerotherapy alone vs. sclerotherapy plus terlipressin vs. sclerotherapy plus octreotide in the treatment of acute variceal haemorrhage [Abstract]. Hepatology 1996; 24: 207A. 207A.
87. Reveille RM, Goff GS, Stiegman GV, Stauffer JT. Combination endoscopic variceal ligation (EVL) and low-volume endoscopic sclerotherapy (ES) for bleeding oesophageal varices: a faster route to variceal eradication? [Abstract]. Gastrointest Endosc 1991; 37: 243. 243.
88. Koutsomanis D. Endoscopic variceal ligation combined with low-volume sclerotherapy: a controlled study [Abstract]. Gastroenterology 1992; 102: A835. A835.
89. Saeed ZA, Stiegman GV, Ramirez RC, Reville M, Goff JS, Hepps KS. et al. Endoscopic variceal ligation is superior to combined ligation and sclerotherapy for esophageal varices: a multi-center prospective randomized trial. Hepatology 1997; 25: 71 -74.
90. Laine L, Stein C, Sharma V. Randomized comparison of ligation vs. ligation plus sclerotherapy in patients with bleeding esophageal varices. Gastroenterology 1996; 110: 529 -533.
91. Bhargava DK, Pokharna R. Endoscopic variceal ligation versus endoscopic variceal ligation and endoscopic sclerotherapy: a prospective randomized study. Am J Gastroenterol 1997; 92: 950 -953.
92. Lo GH, Lai KH, Cheng JS, Chian-Ku Lin, Jia-Shenk Huang, Ping-I Hsu. et al. The additive effect of sclerotherapy to patients receiving repeated endoscopic variceal ligation: a prospective, randomized trial. Hepatology 1998; 28: 391 -395.
93. Masumoto H, Toyonaga A, Oho K, Iwao T, Tanikawa K. Ligation plus low volume sclerotherapy for high risk esophageal varices: comparisons with ligation therapy or sclerotherapy alone. J Gastroenterol 1998; 33: 1 -5.
94. Al Traif I, Sbeih F, Al Jumah AR, Johani M, Al Omair A, Al Bakr F. et al. Randomized trial of ligation vs. combined ligation and sclerotherapy for bleeding esophageal varices. Gastrointest Endosc 1999; 50: 1 -6.
95. Umehara M, Onda M, Tajiri T, Toba M, Yoshiba H, Yamashita K. Sclerotherapy plus ligation versus ligation for the treatment of esophageal varices: prospective randomized study. Gastrointest Endosc 1999; 50: 7 -12.
96. Sarin SK, Gupta R. Endoscopic ligation plus sclerotherapy: two plus two make only three! Gastrointest Endosc 1999; 50: 129 -133.
97. Sarin SK, Lamba GS, Kumar M, Misra A, Murthy NS. A comparison of endoscopic variceal ligation and propranolol for primary prevention of variceal bleeding. N Engl J Med 1999; 340: 988 -993.
98. McCormick PA, Dick R, Panagou EB, Chin JKT, Greenslade L, Burroughs AK. Emergency transjugular intrahepatic portosystemic stent-shunt salvage treatment for uncontrolled variceal bleeding. Br J Surg 1994; 81: 1324 -1327.
99. Jalan R, John TG, Redhead DN, Finlayson NDC, Garden OJ, Hayes PC. A comparative study of the transjugular intrahepatic portosystemic stent-shunt (TIPSS) and oesophageal transection in uncontrolled variceal haemorrhage. Am J Gastroenterol 1995; 11: 1932 -1936.
100. Sanyal AJ, Freedman AM, Luketic VA, Purdum PP, Shiffman ML, Tisnado J. et al. Transjugular intrahepatic portosystemic stent-shunts for patients with active variceal hemorrhage unresponsive to sclerotherapy. Gastroenterology 1996; 111: 138 -146.
101. Banares R, Casado M, Rodriguez-Laiz JM, Camurez F, Matilla A, Echenagusia A. et al. Urgent transjugular intrahepatic portosystemic shunt for control of acute variceal bleeding. Am J Gastroenterol 1998; 93: 75 -79.
102. Gerbes AL, Gulberg V, Waggershauser T, Holl J, Reiser M. Transjugular intrahepatic portosystemic shunt (TIPS) for variceal bleeding in portal hypertension: comparison of emergency and elective interventions. Dig Dis Sci 1998; 43: 2463 -2469.
103. Kamath PS, McKusick MA. Transjugular intrahepatic portosystemic shunts (TIPS). Bailliere's Clinical Gastroenterology 1997; 11: 327 -349.
104. Rosemurgy AS, Goode SE, Zwiebel BR, Black TJ, Brady PG. A prospective trial of transjugular intrahepatic portasystemic stent shunt versus small diameter prosthetic H-graft portacaval shunts in the treatment of bleeding varices. Ann Surg 1996; 224: 378 -386.
105. Cello JP, Crass R, Trunkey DD. Endoscopic sclerotherapy versus esophageal transection in Child's class C patients with variceal hemorrhage. Comparison with results of portacaval shunt. Preliminary report. Surgery 1982; 91: 333 -338.
106. Huizinga WKJ, Angorn PA, Baker WW. Oesophageal transection versus injection sclerotherapy in the management of bleeding oesophageal varices in patients at high risk. Surg Gynecol Obstet 1985; 160: 539 -546.
107. Teres J, Baroni R, Bordas JM, Vias J, Pera C, Rodes J. Randomized trial of portacaval shunt, stapling transection and endoscopic sclerotherapy in uncontrolled variceal bleeding. J Hepatol 1987; 4: 159 -167.
108. Burroughs AK, Hamilton G, Philips A, Mezzanote G, McIntire N, Hobbs KIEF. A comparison of sclerotherapy with staple transection of the esophagus for the emergency control of bleeding from esophageal varices. N Engl J Med 1989; 321: 857 -862.
109. Cello JP, Grendell JH, Crass RA, Weber TE, Trunkey D. Endoscopic sclerotherapy versus portacaval shunt in patients with severe cirrhosis and acute variceal hemorrhage. Long term follow-up. N Engl J Med 1987; 316: 11 -15.
110. Jenkins SA, Shields R. Variceal haemorrhage after failed injection sclerotherapy: the role of emergency oesophageal transection. Br J Surg 1989; 76: 49 -51.
111. Willson PD, Kunkler R, Blair SD, Reynolds KW. Emergency oesophageal transection for uncontrolled variceal haemorrhage. Br J Surg 1994; 81: 992 -995.
112. Mathur SK, Shah SR, Soonawala ZF, Karandikar SS, Nagral SS, Dalvi AN. et al. Transabdominal extensive oesophagogastric devascularization with gastro-oesophageal stapling in the management of acute variceal bleeding. Br J Surg 1997; 84: 413 -417.
113. Rikkers LF, Jin G. Emergency shunt. Role in the present management for variceal bleeding. Arch Surg 1995; 130: 472 -477.
114. Orloff MJ, Orloff MS, Orloff SL, Rambotti M, Girard B. Three decades of experience with emergency portacaval shunt for acutely bleeding esophageal varices in 400 unselected patients with cirrhosis of the liver. J Am Coll Surg 1995; 180: 257 -272.
115. Adam R, Diamond T, Bismuth H. Partial portacaval shunt: renaissance of an old concept. Surgery 1995; 111: 610 -616.
116. Darling CR, Shah DM, Chang BB, Thompson PN, Leather RP. Long-term follow up of poor risk patients undergoing small diameter portacaval shunt. Am J Surg 1992; 164: 225 -228.
117. Rosemurgy AS, McAllister EW, Kearney RE. Prospective study of a prosthetic H-graft portacaval shunt. Am J Surg 1991; 161: 159 -164.
118. Krahenbuhl L, Seiler CA, Buchler MW. Variceal hemorrhage in portal hypertension: role of surgery in the acute and elective situation. Schweiz Med Wochenschr 1999; 129: 631 -638.