Evasion of cytotoxic T lymphocytes by murine cytomegalovirus

Seminars in Immunology

Volumn 13, Issue 1, 2001, Pages 19-26

  Kavanagh, Daniel G ^a   Hill, Ann B ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Cytotoxic T lymphocytes; Immune evasion; Major histocompatability complex class I; Murine cytomegalovirus

Indexed keywords

CD8 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; VIRUS DNA;

ANTIGEN PRESENTATION; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTION; CYTOTOXIC T LYMPHOCYTE; GENE EXPRESSION REGULATION; HOST RESISTANCE; HUMAN; IMMUNOREACTIVITY; NONHUMAN; PROTEIN ASSEMBLY; REVIEW; T LYMPHOCYTE ACTIVATION; VIRUS GENOME;

EID: 0035053623     PISSN: 10445323     EISSN: None     Source Type: Journal    
DOI: 10.1006/smim.2001.0292     Document Type: Article

References (27)

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4. + T lymphocytes
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8. A nonstructural polypeptide encoded by immediate-early transcription unit 1 of murine cytomegalovirus is recognized by cytolytic T lymphocytes
9. Cytolytic T lymphocyte recognition of the murine cytomegalovirus nonstructural immediate-early protein pp89 expressed by recombinant vaccinia virus
10. Efficient processing of an antigenic sequence for presentation by MHC class I molecules depends on its neighboring residues in the protein
11. A nonstructural viral protein expressed by a recombinant vaccinia virus protects against lethal cytomegalovirus infection
12. The putative natural killer decoy early gene m04 (gp34) of murine cytomegalovirus encodes an antigenic peptide recognized by protective antiviral CD8 T cells
13. Late-phase expression of a murine cytomegalovirus immediate-early antigen recognized by cytolytic T lymphocytes
14. Presentation of CMV immediate-early antigen to cytolytic T lymphocytes is selectively prevented by viral genes expressed in the early phase
15. Cytomegalovirus prevents antigen presentation by blocking the transport of peptide-loaded major histocompatibility, complex class I molecules into the medial-Golgi compartment
16. Identification of the mouse cytomegalovirus genomic region affecting major histocompatibility complex class I molecule transport
17. A mouse cytomegalovirus glycoprotein retains MHC class I complexes in the ERGIC/cis-Golgi compartments
18. The immunoevasive function encoded by the mouse cytomegalovirus gene m152 protects the virus against T cell control in vivo
19. A cytomegalovirus glycoprotein reroutes MHC class I complexes to lysosomes for degradation
20. A mouse cytomegalovirus glycoprotein, gp34, forms a complex with folded class I MHC molecules in the ER which is not retained but is transported to the cell surface
21. Characterization of a murine cytomegalovirus class I major histocompatibility, complex (MHC) homolog: Comparison to MHC molecules and to the human cytomegalovirus MHC homolog
22. m144, a murine cytomegalovirus (MCMW)-encoded major histocompatibility complex class homologue, confers tumor resistance to natural killer cell-mediated rejection
23. Inhibition of NK cells by murine CMV-encoded class I MHC homologue m144
24. Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs
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27. Macrophages escape inhibition of major histocompatibility complex class I-dependent antigen presentation by cytomegalovirus