Identification of nuclear-import and cell-cycle regulatory proteins that bind to prothymosin α

Biochemistry and Cell Biology

Volumn 79, Issue 2, 2001, Pages 123-131

  Freire, J ^a   Covelo, G ^a   Sarandeses, C ^a   Diaz Jullien C ^a   Freire, M ^a  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

Cell cycle proteins; Chromatin remodeling; Histone binding proteins; Nuclear transport proteins; Prothymosin

Indexed keywords

AFFINITY CHROMATOGRAPHY; CELLS; DNA; IMMUNOLOGY; PROTEINS; TISSUE;

LUMPHOCYTES; PROTHYMOSIN;

BIOCHEMISTRY;

CYCLIN A; CYCLIN DEPENDENT KINASE 2; CYCLINE; HISTONE H1; HISTONE H2B; HISTONE H3; HISTONE H4; KARYOPHERIN BETA1; PROTEIN RCC1; PROTEIN RCH1; PROTHYMOSIN ALPHA; RAN PROTEIN; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

AFFINITY CHROMATOGRAPHY; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CYCLE; CELL PROLIFERATION; IMMUNOBLOTTING; INTRACELLULAR TRANSPORT; LYMPHOCYTE TRANSFORMATION; NONHUMAN; PROTEIN ANALYSIS; PROTEIN PROTEIN INTERACTION;

ANIMALIA; MAMMALIA;

EID: 0035048090     PISSN: 08298211     EISSN: None     Source Type: Journal    
DOI: 10.1139/o00-098     Document Type: Article

References (41)

1. Prothymosin α is phosphorylated in proliferating stimulated cells
2. Quantitative electrophoresis in polyacrilamide gels of 20-40%
3. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
4. A search for differential polypeptide synthesis throughout the cell cycle of HeLa cells
5. Expression of the rat prothymosin α gene during T-lymphocyte proliferation and liver regeneration
6. Reversal of terminal differentiation and control of DNA replication: Cyclin A and cdk2 specifically localize at subnuclear sites of DNA replication
7. Evidence for nuclear targeting of prothymosin and parathymosin synthesized in situ
8. Cellular levels of thymosin immunoreactive peptides are linked to proliferative events: Evidence for a nuclear site of action
9. Modulation of histone acetyltranferase activity through interaction of Epstein-Barr nuclear antigen 3C with prothymosin alpha
10. Functions of the GTPase Ran in RNA export from the nucleus
11. Prothymosin α binds histones in vitro and shows activity in nucleosome assembly assay
12. Nucleoplasmin cDNA sequence reveals polyglutamic acid tracts and a cluster of sequences homologous to putative nuclear localization
13. The human prothymosin α gene is polymorphic and induced upon growth stimulation: Evidence using a cloned cDNA
14. Isolation and partial sequencing of the human prothymosin α
15. Evidence that the G1-S and G2-M transitions are controlled by different cdc2 proteins in higher eukaryotes
16. The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs
17. 1 is a native peptide in several tissues
18. Isolation and partial sequence of goat spleen prothymosin α
19. The expression of prothymosin α gene in T lymphocytes and leukemic lymphoid cells is tied to lymphocyte proliferation
20. Distribution of prothymosin α in rat tissues
21. Primary structure of rat thymus prothymosin α
22. Identification and molecular cloning of yeast homolog of nucleosome assembly protein I which facilitates nucleosome assembly in vitro
23. PCNA: Structure, functions and interactions
24. Identification of domains involved in nuclear uptake and histone binding of protein N1 of Xenopus laevis
25. Binding of human prothymosin α to the leucine-motif/activation domains of HTLV-I Rex and HIV-1 Rev
26. Identification of DNA replication and cell cycle proteins that interact with PCNA
27. Nuclear targeting of prothymosin α
28. Nucleocytoplasmic transport: Signals, mechanisms and regulation
29. Human prothymosin α: Amino acid sequence and immunologic properties
30. The amino acid sequence of bovine thymus prothymosin α
31. Prothymosin α bind to histone H1 in vitro
32. Human prothymosin α inhibits division of yeast Saccharomyces cerevisiae
33. Transport routes through the nuclear pore complex
34. A 180-kDa protein kinase seems to be responsible for the phosphorylation of prothymosin α observed in proliferating cells
35. Prothymosin alpha expression is associated to cell division in rat testis
36. Mutational analysis of human prothymosin α reveals a bipartite nuclear localization signal
37. Prothymosin α antisense oligomers inhibit myeloma cell division
38. Phosphorylation of human and bovine prothymosin α in vivo
39. Cancer cell cycles
40. Increased and altered DNA binding of p53 by S and G2/M but not G1 cyclin-dependent kinases
41. Stimulation of microtubule aster formation and spindle assembly by the small GTase Ran