The oligomeric nature of Na/K-transport ATPase

Journal of Biochemistry

Volumn 129, Issue 3, 2001, Pages 335-342

  Taniguchi, Kazuya ^a   Kaya, Shunji ^a   Abe, Kazuhiro ^a   Mårdh, Sven ^b  

^a HOKKAIDO UNIVERSITY   (Japan)

^b LINKÖPING UNIVERSITY   (Sweden)

Author keywords

Na K ATPase; Oligomer; P type ATPase; Post Albers scheme; Tetraprotomer

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ADENOSINE TRIPHOSPHATE; OLIGOMER; POTASSIUM ION; SODIUM ION;

ENZYME CONFORMATION; ENZYME PHOSPHORYLATION; HYDROLYSIS; ION TRANSPORT; REVIEW; STOICHIOMETRY;

EID: 0035046029     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a002862     Document Type: Review

References (90)

1. The influence of some cations on an adenosine triphosphatase from peripheral nerves
2. +)-ATPase. III. Purification from the outer medulla of mammalian kidney after selective removal of membrane components by SDS
3. -)-ATPase deduced from complementary DNA
4. Molecular genetics of Na,K-ATPase
5. The Na,K-ATPase
6. Structure/function studies of the gamma subunit of renal Na, K-ATPase
7. The renal Na,K-ATPase ancillary α-subunit
8. Structural organization, ion transport, and energy transduction of P-type ATPases
9. 2+ dependent ATPase from rabbit muscle sarcoplasmic reticulum, deduced from its complementary DNA sequence
10. -)-ATPase
11. Flexibility of an active center in sodium-plus-potassium adenosine triphosphatase
12. Activation by adenosine triphosphate in the phosphorylation kinetics of sodium and potassium ion transport adenosine triphosphatase
13. The (sodium plus potassium)-transport ATPase
14. +-transporting adenosine triphosphatase
15. Binding of divalent cation to phosphoenzyme of sodium- and potassium-transport adenosine triphosphatase
16. +-ATPase by paranitrophenylphosphate (pNPP): Evidence for the oligomeric nature of the enzyme
17. +-ATPase changes out of phase during sequential appearance of reaction intermediates
18. +)-ATPase
19. Crystal structure of the calcium pump of sarcoplasmic reticulum at 2.6 Å resolution
20. -)-activated ATPase; enzymatic and transport properties
21. +)-ATPase: On the number of ATP sites of the functional unit
22. Occluded cations in active transport
23. Is ths sodium pump a functional dimer?
24. The ATP binding sites of P-type ion transport ATPases: Properties, structure, conformations, and mechanism of energy coupling
25. +-ATPase functions
26. +)-ATPase has one functioning phosphorylation site per α subunit
27. Stoichiometrical binding of ligands to less than 160 kilodaltons of Na,K-ATPase
28. + in membrane-bound and soluble protomeric αβ-units of Na,K-ATPase
29. Conformational Transitions in the α-subunit and ion occlusion
30. Preparation of Na,K-ATPase with near maximal specific activity and phosphorylation capacity: Evidence that the reaction mechanism involves all of the sites
31. +-dependent ATPase during the ATPase reaction. Evidence for a dimer structure of the ATPase
32. +-ATPase: Half-of-the subunits cross-linking reactivity suggests and oligomeric structure containing a minimum of four catalytic subunits
33. +-ATPase is the αβ-protomer: De-termination by low-angle laser light scattering photometry coupled with high-performance gel chromatography for substantially simultaneous measurement of ATPase activity and molecular weight
34. 4
35. Functional significance of the oligomeric structure of the Na,K-Pump from radiation inactivation and ligand binding
36. +-ATPase induced by octaethylene glycol dodecyl ether, phosphatidylserine and ATP
37. Distinction between the intermediates in Na-ATPase and Na,K-ATPase reaction
38. +-ATPases
39. +-ATPase
40. Complex kinetic behavior in the Na,K- and Ca-ATPases
41. 2′-O-Dansyl analogs of ATP bind with high affinity to the low affinity ATP site of Na/K-ATPase and reveal the interaction of two ATP sites during catalysis
42. +-ATPase α-chain with pyridoxal 5′-diphospho-5′-adenosine reduces ATP-dependent phosphorylation stoichimetry from half to a quarter
43. Structual studies of Na,K-ATPase
44. +-ATPase
45. Acid-labile ATP and/or ADP/Pi binding to the tetraprotomeric form of Na/K-ATPase accompanying catalytic phosphorylation-dephosphorylation cycle
46. +-ATPase
47. +-ATPase and effect of chaotropic anions
48. Binding of monovalent cations to Na,K-dependent ATPase purified from porcine kidney
49. +-ATPase
50. Structure of the Na,K pump: Crystallization of pure membrane-bound Na,K-ATPase and identification of functional domains of the α-subunit
51. Are the states that occlude rubidium obligatory intermediates of the Na/K-ATPase reaction?
52. A model for active transport of sodium and potassium ions as mediated by a tetrameric enzyme
53. +-ATPase function
54. Simultaneous presence of 0.5 mol of phosphoenzyme and acid labile enzyme bound ATP in pig stomach H/K-ATPase
55. +-ATPase results in opposite changes in tryptophan fluorescence
56. Stoichiometry of phosphorylation to fluorescein 5-isothiocyanate binding in the Ca-ATPase of sarcoplasmic reticulum vesicles
57. i
58. Transient state in the phosphorylation of sodium-and potassium-transport adenosine triphosphatase by adenosine triphosphate
59. +)-ATPases modified with N-[p-(2-benzimidazolyl)phenyl]maleimide
60. Low affinity superphosphorylation of the Na,K-ATPase by ATP
61. --ATPase
62. --ATPase
63. +-ATPase: Evidence for the binding of ATP to the phosphoenzyme
64. 2+-transport ATPase
65. +-ATPase activity by ATP and ADP analogues
66. Conformational change of sodium- and potassium-dependent adenosine triphosphatase: Conformational evidence for the Post-Albers mechanism in Na and K-dependent hydrolysis of ATP
67. +-ATPase
68. --ATPase, at Lys-501 of the α-chain, accepts ATP independent of pyridoxal 5′-diphospho-5′-adenosine modification at Lys-480
69. Lysine 480 is not an essential residue for ATP binding or hydrolysis by Na,K-ATPase
70. Site-directed mutagenesis of the sodium pump: Analysis of mutations to amino acids in the proposed nucleotide binding site by stable oxygen isotope exchange
71. Modification of Lysine 501 in Na,K-ATPase reveals coupling between cation occupancy and changes in the ATP binding domain
72. The catalytic domain of P-Type pumps: Evidence for two nucleotide sites
73. - specificity
74. Organization of the membrane domain of the Na/K-pump
75. 2+-ATPase molecules
76. --ATPase
77. Phosphorylation-dependent changes in the spatial relationship between Ca-ATPase polypeptide chains in sarcoplasmic reticulum membranes
78. Dimerization of gastric H,K-ATPase
79. Reversible changes in light scattering following formation of ADP-sensitive phosphoenzyme in Na,K-ATPase modified with of a N-[p-(2-benzimidazolyl) phenyl]maleimide
80. +-ATPase
81. Oligomeric structure of solubilized Na/K-ATPase linked to E1/E2 conformation
82. Binding of 2′(3′)-O-(2,4,6trinitrophenyl)ADP to soluble αβ protomers of Na,K-ATPase modified with fluorescein isothiocyanate
83. +-activated phosphatase reside on different α-subunits
84. +-ATPase protein
85. Twodimensional crystals and three-dimensional structure of Na,K-ATPase analyzed by electron microscopy
86. +-ATPase calculated by application of single particle analysis to two-dimensional crystal images
87. Twodimensional crystals of membrane-bound gastric H,K-ATPase
88. Thermal denaturation of the Na,K-ATPase provides evidence for α-α oligomeric interaction and γ subunit association with the C-terminal domain
89. +-ATPase: Role of ligand-regulated β·β-inter-actions