Immunization with dendritic cells pulsed with tumor extract increases survival of mice bearing intracranial gliomas

Journal of Neuro-Oncology

Volumn 51, Issue 1, 2001, Pages 1-9

  Ni, H T ^a   Spellman, S R ^a   Jean, W C ^a   Hall, W A ^a   Low, W C ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Dendritic cells; Glioma; Immunotherapy

Indexed keywords

B7 ANTIGEN; CELL EXTRACT; INTERCELLULAR ADHESION MOLECULE 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; TUMOR EXTRACT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL SURVIVAL; CELLULAR IMMUNITY; CONTROLLED STUDY; DELAYED HYPERSENSITIVITY; DENDRITIC CELL; DRUG EFFICACY; EXTRACTION; FLUORESCENCE ACTIVATED CELL SORTER; GLIOMA; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOTHERAPY; IMPLANTATION; INTRACRANIAL TUMOR; MAJOR HISTOCOMPATIBILITY COMPLEX; MIXED LYMPHOCYTE REACTION; MOUSE; NONHUMAN;

ANIMALS; BRAIN NEOPLASMS; CANCER VACCINES; CELL LINE; DENDRITIC CELLS; FEMALE; GLIOMA; HYPERSENSITIVITY, DELAYED; IMMUNIZATION; IMMUNOLOGIC MEMORY; IMMUNOTHERAPY; LYMPHOCYTE CULTURE TEST, MIXED; MEMBRANE PROTEINS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; SURVIVAL ANALYSIS; TISSUE EXTRACTS;

EID: 0035045159     PISSN: 0167594X     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1006452726391     Document Type: Article

References (29)

1. Glioma immunology and immunotherapy
2. Modeulation of T cell function by gliomas
3. Molecular detection of tumor-associated antigens shared by human cutaneous melanomas and gliomas
4. The dendritic cell system and its role in immunogenicity
5. Elevated serum levels of interleukin-10 in patients with metastatic malignant melanoma
6. Recent advances in the study of dendritic cells and follicular dendritic cells
7. Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells
8. The dendritic cells system and its role in immunogenicity
9. Production of IL-10 by melanoma cells: Examination of its role in immunosuppression mediated by melanoma
10. Tumor infiltrating dendritic cells are defective in their antigen-presenting function and inducible B7 expression
11. Peptide-pulsed dendritic cells induce antigen-specific CTL-mediated protective tumor immunity
12. Dendritic cells retrovirally transduced with model tumor antigen gene are therapeutically effective against established pulmonary metastases
13. Dendritic cells as adjuvants for class I major histocompatibility complex-restricted antitumor immunity
14. Regression of tumors in mice vaccined with professional antigen-presenting cells pulsed with tumor extracts
15. Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells
16. Cloned dendritic cells can present exogenous antigens on both MHC class I and class II molecules
17. Culture of dendritic cells from murine bone marrow supplemented with GM-CSF and TNF-alpha
18. Eneration of large numbers of dendritic cells from mouse bone marrow cultures supplemented with GM-CSF
19. Identification of proliferating dendritic cells precursors in mouse blood
20. Propagation of dendritic cell progenitors from normal mouse liver using GMC-SF and their maturational development in the presence of type-I-collagen
21. Murine epidermal langerhans cell mature into potent immunostimulatory dendritic cells in vitro
22. Proliferation dendritic cell progenitors in human blood
23. Therapy of murine tumors with tumor peptide-pulsed dendritic cells: Dependence on T cells, B7 costimulation, and T helper cell 1-associated cytokines
24. Antigen-presenting cells pulsed with unfractionated tumor-derived peptides are potent tumor vaccines
25. Treatment of intracranial gliomas with bone marrow derived dendritic cells pulsed with tumor antigens
26. Interleukin-12 is produced by dendritic cells and mediates T helper 1 development as well as interferon-gamma production by T helper 1 cells
27. Expression of cytokine mRNA in murine splenic dendritic cells and better induction of T cell-derived cytokines by dendritic cells than macrophages during in vitro costimulation assay using specific antigens
28. Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4 T cells