Genetic evidence to exclude the androgen receptor co-factor, ARA70 (NCOA4) as a candidate gene for the causation of undermasculinised genitalia [1]

Clinical Genetics

Volumn 59, Issue 4, 2001, Pages 284-286

  Lim, H N ^a   Hawkins, J R ^a   Hughes, I A ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; ANDROGEN RECEPTOR; ANDROGEN RECEPTOR COFACTOR; NUCLEIC ACID BINDING PROTEIN; UNCLASSIFIED DRUG;

ANDROGEN SYNTHESIS; CLINICAL ARTICLE; FEMALE GENITAL SYSTEM; GENE AMPLIFICATION; GENE MUTATION; GENE REARRANGEMENT; GENETIC ANALYSIS; GENETIC SCREENING; GENITAL SYSTEM DISEASE; HUMAN; HYPOSPADIAS; LETTER; MALE; MALE GENITAL SYSTEM; PRIORITY JOURNAL; RECEPTOR BINDING; SKIN BIOPSY; VIRILIZATION;

DNA MUTATIONAL ANALYSIS; GENITAL DISEASES, MALE; GENOTYPE; HETERODUPLEX ANALYSIS; HUMANS; MALE; MUTATION; ONCOGENE PROTEINS; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; RECEPTORS, ANDROGEN; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

EID: 0035043996     PISSN: 00099163     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-0004.2001.590412.x     Document Type: Letter

References (13)

1. Cloning and characterisation of a specific co-activator, ARA-70, for the androgen receptor in human prostate cells
2. RFG (ARA70, ELE1) interacts with the human androgen receptor in a ligand-dependent fashion, but functions only as a weak coactivator in cotransfection assays
3. Androgen receptor gene mutations identified by SSCP in fourteen subjects with androgen insensitivity syndrome
4. The androgen receptor gene mutations database
5. Phenotypic features, androgen receptor binding, and mutational analysis in 278 clinical cases reported as androgen insensitivity syndrome
6. From estrogen to androgen receptor: A new pathway for sex hormones in prostate
7. Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
8. A lock-docking oligo (dT) primer for 5′ and 3′ RACE PCR
9. Interaction of the putative androgen receptor-specific coactivator ARA70/ELE1 with multiple steroid receptors and identification of an internally deleted isoform
10. Frequent activation of ret protooncogene by fusion with a new activating gene in papillary thyroid carcinomas
11. Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene
12. Resistance to several steroids in two sisters
13. Androgen-in-sensitivity syndrome as a possible coactivator disease